8-K ·Filed Aug 12, 2026

PLX

Protalix BioTherapeutics, Inc.
MIXED
Impact 5/10
Horizondays Processed1mo ago SEC0001104659-26-094433
8-K Item 2.02: Earnings release
Actionable Insight ◆ Mixed

The EPS miss vs elevated Street expectations from Q1's massive beat may pressure the stock near-term, but the underlying product revenue growth and clean balance sheet provide a floor. Monitor the Q3 2026 earnings call for any guidance revision on Elfabrio penetration and PRX-115 enrollment updates.

DirectionMixed
Confidencemedium
Horizondays
Latest settled — T+20d
PLX ▲ +4.20% at T+20d
NEUTRAL call ✓ call won +4.20% · α vs SPY +6.10% · entry $2.62 → $2.73
Next anchor: T+60d in 5w
Latest observation: T+34 +1.55% FF3 residual α
Entry anchored
Aug 11, 07:01 PM ET
via 1-min bar
T+1d
-9.92%
call -9.92% · α -10.62%
$2.36
settled 7w ago
T+5d
-10.31%
call -10.31% · α -9.86%
$2.35
settled 6w ago
T+20d
+4.20%
call +4.20% · α +6.10%
$2.73
settled 22d ago
T+60d
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in 5w

Price Chart

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Executive Summary

Protalix BioTherapeutics reported Q2 2026 revenue of $19.9M, up 27% YoY, and net income of $3.8M ($0.05 EPS), compared to $0.2M net income in Q2 2025. The revenue beat was driven by Elfabrio sales growth, but the EPS of $0.05 was below the Street consensus of $-0.01 (a miss vs the whisper number). The company reiterated full-year 2026 revenue guidance of $78M-$83M, which includes a $25M milestone already received. The stock is likely to trade on the EPS miss relative to elevated expectations from the prior quarter's strong beat, despite solid product revenue growth and a clean balance sheet with $40.7M cash and no debt.

Key Financial Metrics

EPS
$0.05
est $-0.01 · +600.0%
Revenue
$19.9M
est $12.9M · +54.2% · +27.1% YoY
Rating
in line
Guidance
$78.0M-$83.0M
maintained
Gross Margin
60.99%

Key Facts

  • Q2 2026 total revenue $19.9M vs $15.7M YoY (+27%), driven by Elfabrio sales
  • Q2 2026 net income $3.8M ($0.05 diluted EPS) vs $0.2M ($0.00) YoY
  • EPS of $0.05 missed the Street consensus of $-0.01 (a miss vs whisper expectations)
  • Reiterated FY2026 total revenue guidance of $78M-$83M, including $25M milestone already received
  • Cash, equivalents, and short-term deposits $40.7M at June 30, 2026; no debt or warrants outstanding
  • PRX-115 Phase 2 RELEASE trial enrollment ongoing; top-line results expected H2 2027

Financial Impact

Q2 revenue beat internal expectations by $7M vs $12.9M consensus, but EPS of $0.05 was below the Street's $-0.01 whisper (a miss). The $25M milestone was already received in Q1.

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Risk Factors

  • EPS miss vs whisper expectations could trigger profit-taking after Q1's 2300% beat
  • Reliance on Chiesi milestone payments for profitability; core product revenue still sub-scale at ~$20M/quarter
  • PRX-115 Phase 2 data not expected until H2 2027, leaving a long catalyst gap

Market Snapshot

Exchange
NYSE
Sector
Biological Products, (No Diagnostic Substances)
Analyst Consensus
80% bullish (5 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 6 SEC documents filed with EDGAR.

DocumentAccession Number
8-K Filing (Primary)0001104659-26-094433
Document: plx-20260812x8k.htm0001104659-26-094433
Document: 0001104659-26-094433-index-headers.html0001104659-26-094433
Document: 0001104659-26-094433-index.html0001104659-26-094433
Document: 0001104659-26-094433.txt0001104659-26-094433
8-K Data (Synthetic)0001104659-26-094433

US Market Status

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