144 ·Filed Aug 10, 2026

ONC

BeOne Medicines Ltd.
BEARISH
Impact 6/10
Horizondays Processed1mo ago SEC0001950047-26-007895
Form 144 — notice of proposed sale of securities
Actionable Insight ▼ Bearish

CEO is executing a massive pre-arranged selling plan, with over $220M in sales already completed in the past month. The 10b5-1 plan provides legal cover but the magnitude is unusual for a $39.6B company. Monitor for any acceleration of selling or additional Form 144 filings. The stock's OTC listing and mixed institutional sentiment (4 trims, 2 near-exits) add to the caution.

DirectionBearish
Confidencehigh
Horizondays
Latest settled — T+20d
ONC ▼ -2.30% at T+20d
SHORT call ✓ call won +2.30% · α vs SPY +1.24% · entry $359.27 → $351.00
Next anchor: T+60d in 5w
Latest observation: T+34 -2.27% FF3 residual α
Entry anchored
Aug 10, 04:00 PM ET
via 1-min bar
T+1d
-0.06%
call +0.06% · α +0.31%
$359.05
settled 7w ago
T+5d
+2.75%
call -2.75% · α -3.15%
$369.15
settled 7w ago
T+20d
-2.30%
call +2.30% · α +1.24%
$351.00
settled 24d ago
T+60d
—
call — · α —
—
in 5w

Price Chart

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Executive Summary

Chairman and CEO John Oyler filed a Form 144 on August 10, 2026, signaling intent to sell approximately $83.9 million worth of BeOne Medicines (ONC) ADS shares. The filing covers shares acquired via vested stock options and founder shares, and is part of a pre-arranged 10b5-1 trading plan that has already generated over $220 million in sales since mid-July 2026. While the 10b5-1 plan provides some cover, the sheer scale of selling by the CEO is a notable signal.

Key Facts

  • CEO John Oyler filed Form 144 to sell ADS shares valued at approximately $83.9 million.
  • The filing covers 229,115 shares acquired from vested stock options (March 2025) and 11,695 founder shares (October 2014).
  • Oyler has already sold ~$220 million in ONC ADS shares since July 10, 2026 under a 10b5-1 plan.
  • Recent 10b5-1 sales include: $52.99M (Jul 16), $40.89M (Jul 14), $36.36M (Jul 15), $20.16M (Jul 17).
  • The filing also includes sales from the Pan-Oyler Foundation, adding to total insider selling pressure.
  • Market cap is $39.6B; the proposed sale represents ~0.2% of market cap, but cumulative recent sales exceed 0.5%.
  • Institutional activity shows 4 trims and 2 near-exits among top holders in Q2 2026.

Financial Impact

Proposed sale of ~$83.9M in ADS shares by CEO; cumulative 10b5-1 sales since July 10 exceed $220M.

dilutioninsider selling volume

Risk Factors

  • CEO selling at scale may signal lack of confidence in near-term valuation or fundamentals.
  • Cumulative insider selling >0.5% of market cap in 30 days is elevated.
  • OTC listing reduces liquidity and may amplify price impact of large sales.
  • Institutional trimming and near-exits suggest some sophisticated holders are reducing exposure.

Market Snapshot

Exchange
OTC
Sector
Pharmaceutical Preparations
Analyst Consensus
92% bullish (12 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
144 Filing (Primary)0001950047-26-007895
Document: 0001950047-26-007895-index.html0001950047-26-007895
Document: 0001950047-26-007895.txt0001950047-26-007895
19 reports for ONC
Performance horizon
50% Hit rate 2 of 4 directional calls best @ T+20▲ +10.46%Aug 5, 2026
Filters
Rows
Reports for ONC — sortable, filterable
TypeNow
Sep 10, 2026
21d ago
Insider Cluster
NEUTRAL ★ 3/10
$346.51 $350.84▲ +1.25%▲ +1.47%$358.07 (+3.34%)
Sep 3, 2026
29d ago
Insider Cluster
NEUTRAL ★ 2/10
$362.68 $346.51▼ −4.46%▼ −3.31%$358.07 (−1.27%)
Aug 26, 2026
5w ago
8-K
NEUTRAL ★ 2/10
$375.80 $361.78▼ −3.73%▼ −3.61%$358.07 (−4.72%)
Aug 14, 2026
7w ago
Insider Cluster
NEUTRAL ★ 4/10
$347.48 $374.47▲ +7.77%▲ +9.14%$358.07 (+3.05%)
Aug 12, 2026
7w ago
Insider Cluster
NEUTRAL ★ 4/10
$356.01 $369.16▲ +3.69%▲ +5.66%$358.07 (+0.58%)
Aug 10, 2026
7w ago
144
BEARISH ★ 6/10
$359.27 $369.15▼ −2.75%▼ −3.15%$358.07 (+0.33%)
Aug 5, 2026
8w ago
Insider Cluster
NEUTRAL ★ 2/10
$329.80 $356.01▲ +7.95%▲ +6.73%$358.07 (+8.57%)
Aug 5, 2026
8w ago
8-K
BULLISH ★ 7/10
$327.53 $359.05▲ +9.62%▲ +9.27%$358.07 (+9.32%)
Jul 24, 2026
10w ago
Insider Cluster
NEUTRAL ★ 2/10
$325.90 $322.08▼ −1.17%▼ −1.55%$358.07 (+9.87%)
Jul 17, 2026
11w ago
Insider Cluster
BEARISH ★ 5/10
$312.02 $326.77▼ −4.73%▼ −5.41%$358.07 (−14.76%)
Showing 10 of 19

US Market Status

Market Closed — Opens Mon (65h 6m)

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