Institutional Cluster

OMER

OMEROS CORP
NEUTRAL
Impact 4/10
Horizonweeks Processed3mo ago
Institutional cluster: 3 buyers, 1 sellers (bullish)
Actionable Insight • Neutral

The cluster lacks high-conviction fundamental buyers, reducing its signal value. Monitor for a 13D filing or catalyst-driven buying from active managers to confirm a thesis. The 45-day 13F lag means these positions may already be unwound.

DirectionNeutral
Confidencemedium
Horizonweeks
Final — all horizons settled through T+60d
OMER ▲ +86.15% at T+60d
NEUTRAL call ✓ call won +86.15% · α vs SPY +81.75% · entry $10.18 → $18.95
Entry anchored
Jun 11, 01:30 PM ET
via exchange tick
T+1d
-14.19%
call -14.19% · α -14.74%
$8.74
settled 4mo ago
T+5d
-5.30%
call -5.30% · α -5.74%
$9.64
settled 4mo ago
T+20d
+0.88%
call +0.88% · α -1.01%
$10.27
settled 3mo ago
T+60d
+86.15%
call +86.15% · α +81.75%
$18.95
settled 24d ago

Executive Summary

Three institutions (Citadel, Two Sigma, Morgan Stanley) accumulated $7.0M in OMER during Q3 2025, while D.E. Shaw trimmed $821K. The cluster is dominated by quant and passive funds, with no activist or high-conviction value funds involved, suggesting a tactical or rebalancing thesis rather than a fundamental catalyst. The net $6.2M inflow is modest relative to OMER's $738M market cap.

Key Financial Metrics

Direction
accumulating
Buy Value
$13.6M
Sell Value
$4.9M
Net Flow
$6.2M

Institutional Positions

Net institutional flow: $6.2M

▲ Buyers (3)

InstitutionActionChangePosition ValueValue Δ
CitadelDOUBLED+149.3%$1.6M$1.1M
Two SigmaADD+39.3%$3.8M$1.8M
Morgan StanleyADD+46.8%$8.2M$4.1M

▼ Sellers (1)

InstitutionActionChangePrev ValueValue Δ
D.E. ShawTRIM-39%$4.9M-$820.8K

Key Facts

  • 3 buyers added $7.0M in OMER positions during Q3 2025
  • 1 seller (D.E. Shaw) trimmed $821K, reducing its stake by 39%
  • Largest buyer: Morgan Stanley added $4.1M (+46.8% shares)
  • Two Sigma added $1.8M (+39.3% shares)
  • Citadel doubled its position, adding $1.1M (+149.3% shares)
  • Net institutional inflow of ~$6.2M represents ~0.8% of market cap
  • All participants are quant or passive funds — no activist or fundamental value funds involved

Financial Impact

3 institutions accumulated $7.0M in new OMER positions while 1 reduced holdings by $821K, for net inflow of ~$6.2M

institutional ownershipfloat

Risk Factors

  • 13F data is 45+ days stale; positions may have been reversed
  • Quant and passive buying may reflect index rebalancing or algorithmic strategies, not fundamental conviction
  • D.E. Shaw's 39% trim suggests some smart money is reducing exposure
  • Historical calibration shows negative average alpha at T+20 for this segment (-2.04%)

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
70% bullish (10 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-OMER-2025-Q3
10 reports for OMER
Performance horizon
100% Hit rate 3 of 3 directional calls best @ T+20▲ +80.38%Jul 20, 2026
Filters
Rows
Reports for OMER — sortable, filterable
TypeNow
Sep 1, 2026
4w ago
Insider Cluster
NEUTRAL ★ 2/10
$18.75 $19.04▲ +1.55%▲ +1.44%—
Aug 28, 2026
5w ago
Insider Cluster
NEUTRAL ★ 5/10
$18.61 $19.43▲ +4.41%▲ +4.15%—
Aug 25, 2026
5w ago
Insider Cluster
NEUTRAL ★ 3/10
$18.22 $20.13▲ +10.48%▲ +10.26%—
Aug 21, 2026
5w ago
Insider Cluster
NEUTRAL ★ 2/10
$19.32 $21.05▲ +8.95%▲ +7.64%—
Jul 20, 2026
10w ago
8-K
BULLISH ★ 5/10
$9.53 $17.19▲ +80.38%▲ +77.82%—
Jul 6, 2026
12w ago
8-K
NEUTRAL ★ 4/10
$10.34 $11.84▲ +14.51%▲ +15.07%—
Jun 18, 2026
15w ago
8-K
BULLISH ★ 5/10
$10.28 $9.22▼ −10.31%▼ −10.84%—
Jun 11, 2026
16w ago
Institutional Cluster
NEUTRAL ★ 4/10
$10.18 $10.27▲ +0.88%▼ −1.01%—
May 13, 2026
20w ago
8-K
MIXED ★ 6/10
$13.28 $8.74▼ −34.19%▼ −33.33%—
Mar 31, 2026
26w ago
8-K
BULLISH ★ 9/10
$12.08 $14.56▲ +20.53%▲ +10.81%—
Showing 10 of 10

US Market Status

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Report published Jun 11, 2026