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SC 13G ·Filed Oct 5, 2026

OBX

Obsidian Therapeutics, Inc.
NEUTRAL
Impact 4/10
Horizonweeks Processed21d 20h ago SEC0001104659-26-113688
Passive investor 5%+ stake
Actionable Insight • Neutral

Paradigm BioCapital is a healthcare-dedicated fund, and its 6.6% stake adds to the roster of sophisticated biotech investors accumulating Obsidian shares. Monitor for any future conversion to a 13D or additional stake increases, though the current filing explicitly disclaims activist intent.

DirectionNeutral
Confidencehigh
Horizonweeks
Latest settled — T+5d
OBX ▼ -9.30% at T+5d
NEUTRAL call -9.30% · α vs SPY -9.17% · entry $13.22 → $11.99
Next anchor: T+20d in 6d
Latest observation: T+13 +50.56% FF3 residual α
Entry = T+0 close
Oct 5, 2026
via day close
T+1d
-0.15%
call -0.15% · α +0.09%
$13.20
settled 21d ago
T+5d
-9.30%
call -9.30% · α -9.17%
$11.99
settled 15d ago
T+20d
Pending
in 6d
T+60d
Pending
in 2mo

Price Chart

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Executive Summary

Paradigm BioCapital Advisors LP has filed a Schedule 13G disclosing a 6.6% passive stake in Obsidian Therapeutics, Inc. as of September 28, 2026. This is a new filing from a healthcare-focused investment firm, adding to a growing list of notable passive holders (Deep Track Capital, RA Capital, Novo Holdings) that have recently disclosed stakes. The filing signals continued institutional interest in Obsidian but carries no activist intent.

Key Financial Metrics

Stake
6.6%
Investor
Paradigm BioCapital Advisors LP
Investor Type
hedge fund

Key Facts

  • Paradigm BioCapital Advisors LP and related entities beneficially own 4,101,576 shares of Obsidian Therapeutics common stock, representing 6.6% of shares outstanding.
  • The filing is made under Rule 13d-1(c), confirming passive intent with no purpose of changing or influencing control.
  • Paradigm BioCapital International Fund Ltd. directly holds 3,613,771 shares (5.9%), while the remainder is held via separately managed accounts.
  • The stake is based on 61,772,876 shares outstanding as of August 10, 2026, per Obsidian's Form 10-Q.
  • This is a new filing from Paradigm BioCapital; no prior 13G or 13D from this filer was found in the provided context.

Financial Impact

6.6% passive stake valued at an undisclosed amount; no transaction price disclosed.

ownership concentration

Risk Factors

  • Passive 13G filers can convert to activist 13D if circumstances change, though no such signal here.
  • Concentration of institutional ownership may increase stock volatility on fund flows.

Documents Analyzed

This report is based on 4 SEC documents filed with EDGAR.

DocumentAccession Number
SC 13G Filing (Primary)0001104659-26-113688
Document: 0001104659-26-113688-index-headers.html0001104659-26-113688
Document: 0001104659-26-113688-index.html0001104659-26-113688
Document: 0001104659-26-113688.txt0001104659-26-113688
13 reports for OBX
Performance horizon

Track record builds as more directional reports settle.

Filters
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Reports for OBX — sortable, filterable
TypeNow
Oct 5, 2026
21d ago
SC 13G
NEUTRAL ★ 4/10
$13.22awaiting T+20—$14.08 (+6.51%)
Sep 10, 2026
6w ago
EFFECT
BULLISH ★ 8/10
$17.16 $12.24▼ −28.67%▼ −30.80%$14.08 (−17.95%)
Aug 3, 2026
12w ago
3
NEUTRAL ★ 1/10
$34.00 $17.04▼ −49.88%▼ −48.64%$14.08 (−58.59%)
Aug 3, 2026
12w ago
3
NEUTRAL ★ 2/10
$34.00 $17.04▼ −49.88%▼ −48.64%$14.08 (−58.59%)
Aug 3, 2026
12w ago
3
NEUTRAL ★ 2/10
$34.00 $17.04▼ −49.88%▼ −48.64%$14.08 (−58.59%)
Aug 3, 2026
12w ago
3
NEUTRAL ★ 2/10
$34.00 $17.04▼ −49.88%▼ −48.64%$14.08 (−58.59%)
Aug 3, 2026
12w ago
3
NEUTRAL ★ 2/10
$34.00 $17.04▼ −49.88%▼ −48.64%$14.08 (−58.59%)
Aug 3, 2026
12w ago
3
NEUTRAL ★ 1/10
$34.00 $17.04▼ −49.88%▼ −48.64%$14.08 (−58.59%)
Aug 3, 2026
12w ago
8-K
BEARISH ★ 7/10
$34.00 $17.04▲ +49.88%▲ +48.64%$14.08 (+58.59%)
Jul 6, 2026
16w ago
EFFECT
NEUTRAL ★ 5/10
—awaiting T+20——
Showing 10 of 13

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Report published Oct 5, 2026