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Institutional Cluster ·Filed Sep 22, 2026

OBIO

Orchestra BioMed Holdings, Inc.
NEUTRAL
Impact 3/10
Horizonweeks Processed1mo ago
Institutional cluster: 13 buyers, 6 sellers (bullish)
Actionable Insight • Neutral

Monitor next 13F filing (Q3 2026) to see if the passive buying persisted or reversed — the 45-day lag makes current data stale. No active fundamental manager initiated a new position, suggesting the buying is index-driven rather than thesis-driven.

DirectionNeutral
Confidencemedium
Horizonweeks
Latest settled — T+20d
OBIO ▼ -6.43% at T+20d
NEUTRAL call -6.43% · α vs SPY -5.87% · entry $6.22 → $5.82
Next anchor: T+60d in 7w
Latest observation: T+23 -24.27% FF3 residual α
Entry = T+0 close
Sep 22, 2026
via day close
T+1d
-4.66%
call -4.66% · α -3.94%
$5.93
settled 5w ago
T+5d
-2.25%
call -2.25% · α -1.06%
$6.08
settled 28d ago
T+20d
-6.43%
call -6.43% · α -5.87%
$5.82
settled 7d ago
T+60d
Pending
in 7w

Executive Summary

In Q2 2026, 13 institutional buyers added $13.2M in net new OBIO positions, overwhelmingly driven by mega-passive funds (BlackRock, Geode, UBS, Northern Trust) doubling or adding shares, while only 6 sellers trimmed a combined $786K. The cluster is dominated by passive/index rebalancing rather than active conviction, and the 45-day reporting lag means these positions may already be stale.

Key Financial Metrics

Direction
accumulating
Buy Value
$20.1M
Net Flow
$13.2M

Institutional Positions

Net institutional flow: $13.2M

▲ Buyers (13)

InstitutionActionChangePosition ValueValue Δ
BlackRockDOUBLED+294.9%$10.8M$8.1M
GeodeDOUBLED+107.6%$4.4M$2.3M
Northern TrustDOUBLED+190.5%$1.5M$980.0K
UBSDOUBLED+547.5%$1.4M$1.2M
SchwabADD+31.7%$1.5M$380.0K
RenTechADD+26.9%$388.0K$87.0K

▼ Sellers (6)

InstitutionActionChangePrev ValueValue Δ
FidelityNEAR_EXIT-98.5%$77.0K-$76.0K
BarclaysNEAR_EXIT-77.2%$252.0K-$194.0K
Jane Street GroupTRIM-72.4%$237.0K-$170.0K
BofATRIM-54.8%$224.0K-$121.0K
Susquehanna International GroupTRIM-32.5%$414.0K-$131.0K
CitadelTRIM-29%$337.0K-$94.0K

Key Facts

  • 13 institutional buyers added $13.2M in net new OBIO positions during Q2 2026
  • 6 sellers reduced holdings by a combined $786K
  • BlackRock doubled its stake to 2.51M shares ($10.8M), accounting for over half of total buying value
  • Geode, UBS, and Northern Trust all doubled their positions
  • Fidelity and Barclays nearly exited entirely, while Citadel, Susquehanna, and Jane Street trimmed
  • The buyer list is dominated by mega-passive/index funds, not active fundamental managers

Financial Impact

13 institutions accumulated $13.2M in net new OBIO positions while 6 sellers reduced holdings by $786K; total buyer holdings reached $20.1M

institutional ownershipfloat turnover

Risk Factors

  • 13F data is 45+ days stale; positions may have been unwound since quarter-end
  • Passive/index fund buying carries weaker signal than active manager conviction
  • No activist or deep-value fund initiated a position, limiting the thesis signal

Investment Themes

Healthcare & Medical Devices

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-OBIO-2026-Q2
11 reports for OBIO
Performance horizon
0% Hit rate @ T+5 0 of 3 directional calls Went positive at some point 0 of 3 best @ T+1▼ −0.48%Apr 23, 2026
Filters
Rows
Reports for OBIO — sortable, filterable
TypeNow
Oct 1, 2026
26d ago
144
NEUTRAL ★ 3/10
$6.35 $5.73▼ −9.76%▼ −11.06%—
Oct 1, 2026
26d ago
8-K
BULLISH ★ 6/10
$6.35 $5.73▼ −9.76%▼ −11.06%—
Sep 22, 2026
4w ago
Institutional Cluster
NEUTRAL ★ 3/10
$6.22 $6.08▼ −2.25%▼ −1.06%—
Sep 8, 2026
7w ago
Insider Cluster
NEUTRAL ★ 3/10
$5.43 $6.04▲ +11.23%▲ +12.35%—
Sep 1, 2026
8w ago
144
BEARISH ★ 4/10
$4.90 $5.45▼ −11.22%▼ −11.14%—
Jul 1, 2026
16w ago
144
NEUTRAL ★ 2/10
$4.30 $3.96▼ −7.91%▼ −8.17%—
Jun 2, 2026
20w ago
Insider Cluster
NEUTRAL ★ 2/10
$3.86 $4.02▲ +4.15%▲ +7.96%—
May 19, 2026
23w ago
Insider Cluster
NEUTRAL ★ 2/10
$4.00 $4.06▲ +1.50%▼ −0.75%—
Apr 29, 2026
25w ago
DEFA14A
NEUTRAL ★ 2/10
$3.99 $3.93▼ −1.50%▼ −3.23%—
Apr 23, 2026
26w ago
Press Release
BULLISH ★ 7/10
$4.15 $3.80▼ −8.43%▼ −9.91%—
Showing 10 of 11

US Market Status

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Report published Sep 22, 2026