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8-K ·Filed Apr 10, 2026

MTVA

MetaVia Inc.
NEUTRAL
Impact 5/10
Horizonmonths Processed6mo ago SEC0001104659-26-041784
8-K context-dependent: Items 7.01
Actionable Insight • Neutral

Monitor for clinical data in Q4 2026 that could validate DA-1726's efficacy and tolerability profile compared to existing GLP-1 therapies

DirectionNeutral
Confidencehigh
Horizonmonths
Final — all horizons settled through T+60d
MTVA ▲ +12.06% at T+60d
NEUTRAL call +12.06% · α vs SPY +1.73% · entry $1.41 → $1.58
Entry = T+0 close
Apr 10, 2026
via day close
T+1d
+6.38%
call +6.38% · α +5.41%
$1.50
settled 7mo ago
T+5d
-0.71%
call -0.71% · α -5.21%
$1.40
settled 6mo ago
T+20d
-5.67%
call -5.67% · α -14.20%
$1.33
settled 6mo ago
T+60d
+12.06%
call +12.06% · α +1.73%
$1.58
settled 4mo ago

Price Chart

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Executive Summary

MetaVia Inc. announced the first patient dosing in Part 3 of its Phase 1 clinical trial for DA-1726, a dual GLP-1/glucagon agonist for obesity. The trial evaluates higher-dose regimens to improve efficacy and tolerability, with data expected in Q4 2026.

Key Facts

  • First patient dosed in Part 3 of Phase 1 trial for DA-1726
  • Part 3 evaluates one-step (48 mg) and two-step (64 mg) dose titration regimens
  • Study includes 40 obese, otherwise healthy adult subjects
  • Primary endpoints: safety, tolerability, adverse events
  • Secondary endpoints: weight loss, waist circumference, glycemic control
  • Data expected in Q4 2026

Financial Impact

No financial impact disclosed

Risk Factors

  • Clinical trial may not demonstrate improved efficacy or tolerability
  • Potential safety issues in higher-dose cohorts
  • Competitive landscape with established GLP-1 therapies

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations

Investment Themes

Documents Analyzed

This report is based on 5 SEC documents filed with EDGAR.

DocumentAccession Number
8-K Filing (Primary)0001104659-26-041784
Document: mtva-20260410xex99d1.htm0001104659-26-041784
Document: 0001104659-26-041784-index-headers.html0001104659-26-041784
Document: 0001104659-26-041784-index.html0001104659-26-041784
Document: 0001104659-26-041784.txt0001104659-26-041784
13 reports for MTVA
Performance horizon
33% Hit rate @ T+20 1 of 3 directional calls Went positive at some point 1 of 3 best @ T+20▲ +2.70%Jul 2, 2026
Filters
Rows
Reports for MTVA — sortable, filterable
TypeNow
Oct 13, 2026
13d ago
3
NEUTRAL ★ 2/10
$1.36awaiting T+20—$1.22 (−10.66%)
Oct 13, 2026
13d ago
8-K
NEUTRAL ★ 3/10
$1.43awaiting T+20—$1.22 (−15.03%)
Sep 9, 2026
6w ago
8-K
NEUTRAL ★ 4/10
$1.74 $1.46▼ −16.09%▼ −18.04%$1.22 (−30.17%)
Jul 9, 2026
15w ago
8-K
NEUTRAL ★ 3/10
$1.73 $1.45▼ −16.18%▼ −18.43%$1.22 (−29.77%)
Jul 2, 2026
16w ago
424B5
BEARISH ★ 6/10
$1.48 $1.44▲ +2.70%▲ +2.29%$1.22 (+17.91%)
Jun 8, 2026
20w ago
8-K
MIXED ★ 6/10
$1.89 $1.58▼ −16.40%▼ −17.85%$1.22 (−35.71%)
Jun 8, 2026
20w ago
8-K
BULLISH ★ 6/10
$2.22 $1.51▼ −31.98%▼ −33.61%$1.22 (−45.27%)
May 27, 2026
21w ago
8-K
BULLISH ★ 6/10
$3.34 $1.53▼ −54.19%▼ −52.29%$1.22 (−63.62%)
May 18, 2026
23w ago
8-K
NEUTRAL ★ 4/10
$1.11 $1.65▲ +48.65%▲ +47.07%$1.22 (+9.46%)
May 14, 2026
23w ago
8-K
NEUTRAL ★ 4/10
$1.11 $1.71▲ +54.05%▲ +51.94%$1.22 (+9.46%)
Showing 10 of 13

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Report published Apr 10, 2026