S-3 ·Filed Apr 3, 2026

LYEL

Lyell Immunopharma, Inc.
NEUTRAL
Impact 2/10
Horizonweeks Processed6mo ago SEC0001193125-26-142213
Shelf registration — potential dilution
Actionable Insight • Neutral

Monitor for actual sales by the selling stockholders, particularly ARCH Venture Fund, Gates Frontier, and Explore Investments, as these could create downward pressure on the stock. The recent $25M in insider buying suggests confidence in the company's prospects despite this resale registration. The lack of proceeds to the company means this is purely a liquidity event for existing investors rather than a capital raise.

DirectionNeutral
Confidencehigh
Horizonweeks
Final — all horizons settled through T+60d
LYEL ▼ -40.20% at T+60d
NEUTRAL call ✗ call lost -40.20% · α vs SPY -53.67% · entry $21.69 → $12.97
Entry anchored
Apr 2, 03:59 PM ET
via exchange tick
T+1d
+0.41%
call +0.41% · α +0.35%
$21.78
settled 6mo ago
T+5d
+14.34%
call +14.34% · α +10.20%
$24.80
settled 6mo ago
T+20d
-4.47%
call -4.47% · α -13.45%
$20.72
settled 5mo ago
T+60d
-40.20%
call -40.20% · α -53.67%
$12.97
settled 3mo ago

Price Chart

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Executive Summary

Lyell Immunopharma has filed an S-3 shelf registration to allow selling stockholders to resell 1,952,360 shares of common stock acquired in a private placement on March 6, 2026. The company will not receive any proceeds from these sales, which were originally purchased at $25.61 per share in a milestone closing. The registration enables liquidity for institutional investors including ARCH Venture Fund, Gates Frontier, and Explore Investments.

Key Financial Metrics

Offering Size
$37.7M
Dilution
8.37%

Key Facts

  • S-3 filing registers 1,952,360 shares for resale by selling stockholders from a March 6, 2026 private placement
  • Company will not receive any proceeds from the resale of these shares
  • Shares were acquired at $25.61 per share in a milestone closing under a July 2025 Securities Purchase Agreement
  • Selling stockholders include ARCH Venture Fund XIII, Euler Fund, Gates Frontier LLC, and Explore Investments LLC
  • Registration fee of $5,200.99 calculated based on $19.29 per share (average of March 27, 2026 Nasdaq high/low)
  • Company recently had $25M in insider buying over the past 30 days

Financial Impact

Potential dilution of 8.4% based on 23,328,390 shares outstanding, with maximum aggregate offering price of $37.66M

dilutionshare countmarket cap

Risk Factors

  • Potential share price pressure if selling stockholders liquidate positions
  • Perception of negative sentiment despite company not receiving proceeds
  • Concentration risk with four primary selling stockholders

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 7 SEC documents filed with EDGAR.

DocumentAccession Number
S-3 Filing (Primary)0001193125-26-142213
Document: d122816dexfilingfees.htm0001193125-26-142213
Document: d122816dex51.htm0001193125-26-142213
Document: d122816dex231.htm0001193125-26-142213
Document: 0001193125-26-142213-index-headers.html0001193125-26-142213
Document: 0001193125-26-142213-index.html0001193125-26-142213
Document: 0001193125-26-142213.txt0001193125-26-142213
13 reports for LYEL
Performance horizon

Track record builds as more directional reports settle.

Filters
Rows
Reports for LYEL — sortable, filterable
TypeNow
Aug 25, 2026
5w ago
Insider Cluster
NEUTRAL ★ 4/10
$15.49 $10.53▼ −32.02%▼ −33.00%$9.26 (−40.22%)
Jul 22, 2026
10w ago
EFFECT
NEUTRAL ★ 4/10
$12.84 $15.76▲ +22.74%▲ +19.84%$9.26 (−27.88%)
Jun 15, 2026
15w ago
Insider Cluster
NEUTRAL ★ 2/10
$12.44 $13.40▲ +7.72%▲ +7.52%$9.26 (−25.56%)
Jun 12, 2026
16w ago
Press Release
NEUTRAL ★ 4/10
$13.50 $15.01▲ +11.19%▲ +9.41%$9.26 (−31.41%)
Jun 8, 2026
16w ago
Press Release
BULLISH ★ 7/10
$12.31 $14.04▲ +14.05%▲ +12.42%$9.26 (−24.78%)
Jun 4, 2026
17w ago
Press Release
NEUTRAL ★ 3/10
$11.97 $14.04▲ +17.29%▲ +15.43%$9.26 (−22.64%)
Apr 24, 2026
23w ago
DEFA14A
NEUTRAL ★ 3/10
$22.62 $16.37▼ −27.63%▼ −32.59%$9.26 (−59.06%)
Apr 15, 2026
24w ago
EFFECT
NEUTRAL ★ 2/10
$23.84 $19.25▼ −19.25%▼ −25.30%$9.26 (−61.16%)
Apr 3, 2026
26w ago
S-3
NEUTRAL ★ 2/10
$21.69 $20.72▼ −4.47%▼ −13.45%$9.26 (−57.31%)
Mar 12, 2026
29w ago
Press Release
MIXED ★ 6/10
$21.25 $24.80▲ +16.71%▲ +13.12%$9.26 (−56.42%)
Showing 10 of 13

US Market Status

Market Closed — Opens Mon (38h 35m)

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