Insider Cluster (2 insiders) ·Filed Mar 6, 2026

LYEL

Lyell Immunopharma, Inc.
BULLISH
Impact 8/10
Horizonweeks Processed6mo ago
Insider cluster: 2 insiders, $25.0M total
Actionable Insight ▲ Bullish

This level of coordinated buying by a sophisticated biotech investor like ARCH Venture Partners is highly unusual and suggests strong conviction ahead of potential clinical or strategic developments. Traders should watch for upcoming catalysts such as trial readouts, partnerships, or funding news.

DirectionBullish
Confidencehigh
Horizonweeks
Final — all horizons settled through T+60d ⚠ clustered
LYEL ▼ -23.64% at T+60d
LONG call ✗ call lost -23.64% · α vs SPY -36.42% · entry $22.46 → $17.15
Entry anchored
Mar 5, 03:59 PM ET
via exchange tick
T+1d
+13.54%
call +13.54% · α +12.69%
$25.50
settled 7mo ago
T+5d
-5.39%
call -5.39% · α -3.86%
$21.25
settled 7mo ago
T+20d
-3.43%
call -3.43% · α -1.38%
$21.69
settled 6mo ago
T+60d
-23.64%
call -23.64% · α -36.42%
$17.15
settled 4mo ago

Price Chart

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Executive Summary

Two funds affiliated with ARCH Venture Partners collectively purchased nearly $25 million worth of Lyell Immunopharma shares in open-market transactions at $25.61 per share. This represents a significant, coordinated investment by a major biotech venture firm, signaling strong confidence in the company's future prospects.

Key Financial Metrics

Direction
buying
Total Value
$25.0M
Insiders
2

Key Facts

  • ARCH Venture Partners IX, LLC purchased 488,090 shares at $25.61 for $12,500,000
  • ARCH Venture Fund XIII, L.P. purchased 488,090 shares at $25.61 for $12,500,000
  • Total open-market purchases: $25.0M across two affiliated funds
  • Transactions occurred on 2026-03-06 in a single day
  • Combined purchase represents approximately 5.2% of Lyell's $477M market cap

Financial Impact

$25.0 million in insider buying, equivalent to 5.2% of market capitalization

market sentimentshare ownershipinvestor confidence

Risk Factors

  • The purchases were made by affiliated funds, not company insiders (executives or directors), so this reflects investor confidence rather than direct management sentiment
  • Biotech stocks are inherently volatile and sensitive to clinical trial outcomes

Market Snapshot

Exchange
Nasdaq

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CONTEXT: Insider Cluster Data (2 trades, 7d window)cluster-LYEL-1773088624224
13 reports for LYEL
Performance horizon

Track record builds as more directional reports settle.

Filters
Rows
Reports for LYEL — sortable, filterable
TypeNow
Aug 25, 2026
5w ago
Insider Cluster
NEUTRAL ★ 4/10
$15.49 $10.53▼ −32.02%▼ −33.00%$9.33 (−39.77%)
Jul 22, 2026
10w ago
EFFECT
NEUTRAL ★ 4/10
$12.84 $15.76▲ +22.74%▲ +19.84%$9.33 (−27.34%)
Jun 15, 2026
15w ago
Insider Cluster
NEUTRAL ★ 2/10
$12.44 $13.40▲ +7.72%▲ +7.52%$9.33 (−25.00%)
Jun 12, 2026
16w ago
Press Release
NEUTRAL ★ 4/10
$13.50 $15.01▲ +11.19%▲ +9.41%$9.33 (−30.89%)
Jun 8, 2026
16w ago
Press Release
BULLISH ★ 7/10
$12.31 $14.04▲ +14.05%▲ +12.42%$9.33 (−24.21%)
Jun 4, 2026
17w ago
Press Release
NEUTRAL ★ 3/10
$11.97 $14.04▲ +17.29%▲ +15.43%$9.33 (−22.06%)
Apr 24, 2026
22w ago
DEFA14A
NEUTRAL ★ 3/10
$22.62 $16.37▼ −27.63%▼ −32.59%$9.33 (−58.75%)
Apr 15, 2026
24w ago
EFFECT
NEUTRAL ★ 2/10
$23.84 $19.25▼ −19.25%▼ −25.30%$9.33 (−60.86%)
Apr 3, 2026
25w ago
S-3
NEUTRAL ★ 2/10
$21.69 $20.72▼ −4.47%▼ −13.45%$9.33 (−56.98%)
Mar 12, 2026
29w ago
Press Release
MIXED ★ 6/10
$21.25 $24.80▲ +16.71%▲ +13.12%$9.33 (−56.09%)
Showing 10 of 13

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Report published Mar 9, 2026