Institutional Cluster

INO

INOVIO PHARMACEUTICALS, INC.
NEUTRAL
Impact 3/10
Horizonweeks Processed3mo ago
Institutional cluster: 3 buyers, 1 sellers (bullish)
Actionable Insight • Neutral

The cluster is entirely passive rebalancing with no active manager conviction — treat as noise. Monitor for any active fund 13D filing or insider buying as a stronger signal. The 34% historical win rate for score-6 filings in this segment suggests fading the passive buying would have been the correct trade historically.

DirectionNeutral
Confidencemedium
Horizonweeks
Final — all horizons settled through T+60d
INO ▲ +30.00% at T+60d
NEUTRAL call ✓ call won +30.00% · α vs SPY +25.60% · entry $1.10 → $1.43
Entry anchored
Jun 10, 03:59 PM ET
via exchange tick
T+1d
0.00%
call 0.00% · α -0.54%
$1.10
settled 4mo ago
T+5d
+0.91%
call +0.91% · α +0.48%
$1.11
settled 4mo ago
T+20d
+8.18%
call +8.18% · α +6.29%
$1.19
settled 3mo ago
T+60d
+30.00%
call +30.00% · α +25.60%
$1.43
settled 24d ago

Executive Summary

Three mega-passive institutional investors (Vanguard, State Street, Morgan Stanley) added to their INO positions in Q3 2025, increasing aggregate holdings by $3.5M to $8.6M, while Fidelity nearly exited its stake. The buying is dominated by passive index rebalancing, not active conviction, and the $90M market cap makes these dollar amounts immaterial for the broader market. Historical calibration shows a 34% observed win rate for score-6 filings in this segment, with negative average alpha, suggesting limited directional signal.

Key Financial Metrics

Direction
accumulating
Buy Value
$8.6M
Sell Value
$174.7K
Net Flow
$3.3M

Institutional Positions

Net institutional flow: $3.3M

▲ Buyers (3)

InstitutionActionChangePosition ValueValue Δ
VanguardADD+35%$6.3M$2.3M
State StreetADD+50.6%$436.0K$184.0K
Morgan StanleyADD+95.8%$1.8M$1.0M

▼ Sellers (1)

InstitutionActionChangePrev ValueValue Δ
FidelityNEAR_EXIT-98.5%$178.0K-$174.7K

Key Facts

  • 3 mega-passive funds added $3.5M net to INO positions in Q3 2025
  • Vanguard increased by 35% (703.7K shares), now holding $6.3M
  • Morgan Stanley nearly doubled its stake (+95.8%), adding $1.0M
  • Fidelity exited 98.5% of its position, selling $174.7K
  • All activity is from passive/index managers, not active or activist funds
  • Historical calibration: score-6 filings in this segment have 34% win rate and -2.84% avg alpha at T+20

Financial Impact

3 passive buyers added $3.5M in new holdings; 1 passive seller reduced by $174.7K. Net institutional inflow of ~$3.3M, representing ~3.7% of INO's $90M market cap.

institutional ownershipfloat

Risk Factors

  • Passive buying may reverse next quarter on index rebalancing
  • 13F data is 45+ days stale; positions may have already been unwound
  • Micro-cap ($90M) has limited liquidity and high volatility

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
70% bullish (10 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-INO-2025-Q3
8 reports for INO
Performance horizon
86% Hit rate 6 of 7 directional calls best @ T+20▲ +46.23%Jul 2, 2026
Filters
Rows
Reports for INO — sortable, filterable
TypeNow
Jul 31, 2026
9w ago
8-K
BEARISH ★ 6/10
$0.6770 $1.29▼ −90.55%▼ −87.56%—
Jul 30, 2026
9w ago
424B5
BEARISH ★ 6/10
$0.6770 $1.29▼ −90.55%▼ −87.56%—
Jul 30, 2026
9w ago
Press Release
BEARISH ★ 7/10
$0.6560 $1.26▼ −92.07%▼ −88.11%—
Jul 13, 2026
11w ago
EFFECT
BEARISH ★ 6/10
$1.16 $0.7364▲ +36.52%▲ +39.70%—
Jul 2, 2026
13w ago
S-3
BEARISH ★ 6/10
$1.22 $0.6560▲ +46.23%▲ +45.81%—
Jun 11, 2026
16w ago
Institutional Cluster
NEUTRAL ★ 3/10
$1.10 $1.19▲ +8.18%▲ +6.29%—
Apr 6, 2026
25w ago
8-K
BEARISH ★ 6/10
$1.13 $1.14▼ −0.89%▲ +8.10%—
Apr 2, 2026
26w ago
424B5
BEARISH ★ 6/10
$1.13 $1.12▲ +0.89%▲ +10.76%—
Showing 8 of 8

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Report published Jun 11, 2026