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Insider Cluster (2 insiders) ·Filed May 7, 2026

HOWL

Werewolf Therapeutics, Inc.
BEARISH
Impact 6/10
Horizonweeks Processed5mo ago
Insider cluster: 2 insiders, $299K total
Actionable Insight ▼ Bearish

The insider sales, while not by C-suite executives, are material relative to market cap and come right after a strategic update that included an asset sale and debt repayment. The company's cash runway is limited ($46.5M at Q1 end) and it is actively seeking strategic alternatives — this could signal insider pessimism about the outcome. Watch for any 8-K regarding a potential sale, merger, or wind-down, and monitor cash burn in the next 10-Q.

DirectionBearish
Confidencemedium
Horizonweeks
Final — all horizons settled through T+60d
HOWL ▼ -40.88% at T+60d
SHORT call ✓ call won +40.88% · α vs SPY +45.51% · entry $0.6800 → $0.4020
Entry = T+0 close
May 7, 2026
via day close
T+1d
-2.79%
call +2.79% · α +3.02%
$0.6610
settled 6mo ago
T+5d
-24.26%
call +24.26% · α +24.47%
$0.5150
settled 6mo ago
T+20d
-43.82%
call +43.82% · α +44.04%
$0.3820
settled 5mo ago
T+60d
-40.88%
call +40.88% · α +45.51%
$0.4020
settled 3mo ago

Price Chart

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Executive Summary

Two insiders at Werewolf Therapeutics sold a total of $299K in open-market sales over a 7-day window, representing ~0.9% of the company's $32M market cap. The sales follow the company's Q1 2026 earnings release, which disclosed a net loss of $13.5M, an asset sale to Jazz Pharmaceuticals, and repayment of all K2 debt, while the company continues to explore strategic alternatives. The cluster is notable for its size relative to market cap and the proximity to the earnings announcement, but the sales are by a director and a 10% owner, not C-suite executives.

Key Financial Metrics

Direction
selling
Total Value
$299.0K
Insiders
2

Key Facts

  • Total insider sales of $299K represent ~0.9% of $32M market cap — significant for a micro-cap biotech
  • Sales occurred within 5 days of Q1 2026 earnings (May 7) and after Jazz asset purchase agreement and K2 debt repayment
  • RA Capital Management (10% owner) sold 351.5K shares for $250K on May 8; Director Luke Evnin sold 93.7K shares for $60K on May 6-7
  • Q1 2026 net loss was $13.5M vs $18.1M YoY; cash burn continues with $46.5M cash at quarter-end
  • Company is exploring strategic options with Piper Sandler; no C-suite insiders sold in this cluster

Financial Impact

Insider sales of $299K represent 0.9% of market cap; Q1 net loss of $13.5M; cash burn rate ~$10M/quarter

cashnet lossinsider ownership

Risk Factors

  • Insider selling at 0.9% of market cap in a micro-cap biotech with limited cash runway is a bearish signal
  • Company is exploring strategic alternatives — could result in a dilutive financing, asset sale at unfavorable terms, or wind-down
  • No C-suite buying to offset selling; RA Capital is a significant holder reducing its position

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
80% bullish (10 analysts)

Investment Themes

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-HOWL-1778624823979
25 reports for HOWL
Performance horizon
79% Hit rate @ T+5 11 of 14 directional calls Went positive at some point 12 of 14 best @ T+60▲ +51.32%Apr 27, 2026
Filters
Rows
Reports for HOWL — sortable, filterable
TypeNow
Oct 26, 2026
today
S-4/A
BEARISH ★ 5/10
$0.9806awaiting T+5—$1.02 (−4.02%)
Sep 22, 2026
4w ago
S-4
BEARISH ★ 7/10
$0.9894 $0.9223▲ +6.78%▲ +6.11%$1.02 (−3.09%)
Sep 21, 2026
5w ago
SC 13G
NEUTRAL ★ 3/10
$0.9800 $0.9300▼ −5.10%▼ −4.08%$1.02 (+4.08%)
Aug 21, 2026
9w ago
425
BULLISH ★ 7/10
$0.8740 $0.9433▲ +7.93%▲ +7.46%$1.02 (+16.70%)
Aug 21, 2026
9w ago
8-K
BULLISH ★ 7/10
$0.8740 $0.9433▲ +7.93%▲ +7.46%$1.02 (+16.70%)
Aug 21, 2026
9w ago
Press Release
BEARISH ★ 7/10
$0.8740 $0.9433▼ −7.93%▼ −7.46%$1.02 (−16.70%)
Jul 31, 2026
12w ago
8-K
MIXED ★ 5/10
$0.3531 $0.3971▲ +12.46%▲ +8.95%$1.02 (+188.87%)
Jul 31, 2026
12w ago
Press Release
MIXED ★ 5/10
$0.3531 $0.3971▲ +12.46%▲ +8.95%$1.02 (+188.87%)
Jun 29, 2026
17w ago
144
BEARISH ★ 6/10
$0.3599 $0.3200▲ +11.09%▲ +11.69%$1.02 (−183.41%)
Jun 29, 2026
17w ago
144
BEARISH ★ 6/10
$0.3599 $0.3200▲ +11.09%▲ +11.69%$1.02 (−183.41%)
Showing 10 of 25

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Report published May 12, 2026