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SC 13D/A ·Filed Sep 28, 2026

GOSS

Gossamer Bio, Inc.
BEARISH
Impact 6/10
Horizonweeks Processed27d 15h ago SEC0001104659-26-111463
Activist stake amendment (position change)
Actionable Insight ▼ Bearish

D. E. Shaw's crossing below 5% and disclosed short positions suggest the activist campaign is winding down rather than escalating. The board seat gained (Ciongoli) may provide some ongoing influence, but the selling pattern indicates reduced conviction. Monitor for further 13D amendments or a move to 13G filing if ownership continues to decline.

DirectionBearish
Confidencehigh
Horizonweeks
Latest settled — T+5d
GOSS ▼ -6.91% at T+5d
SHORT call ✓ call won +6.91% · α vs SPY +8.86% · entry $11.58 → $10.78
Next anchor: T+20d due 3h ago
Latest observation: T+18 +22.08% FF3 residual α
Entry = T+0 close
Sep 28, 2026
via day close
T+1d
+2.33%
call -2.33% · α -2.54%
$11.85
settled 27d ago
T+5d
-6.91%
call +6.91% · α +8.86%
$10.78
settled 21d ago
T+20d
Pending
due 3h ago
T+60d
Pending
in 8w

Price Chart

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Executive Summary

D. E. Shaw's Amendment No. 4 to its Schedule 13D on Gossamer Bio reports that its Valence portfolio crossed below the 5% beneficial ownership threshold on September 24, 2026, now holding 4.9% of outstanding shares (296,858 post-split shares). The filing also discloses that Valence and Cogence maintain open short positions referencing 44,364 and 2,290 common shares, respectively, following the 1-for-80 reverse stock split that became effective September 10, 2026. This marks a significant de-escalation from D. E. Shaw's prior activist posture, as the group's aggregate beneficial ownership dropped from above 5% to 5.1% (312,048 shares) and the primary activist vehicle fell below the 5% reporting threshold.

Key Financial Metrics

Stake
5.1%
Investor
D. E. Shaw & Co., L.P.

Key Facts

  • D. E. Shaw Valence Portfolios, L.L.C. ceased to be a >5% beneficial owner on September 24, 2026, now holding 4.9% (296,858 shares).
  • Aggregate D. E. Shaw group ownership is 312,048 shares (5.1%) post-reverse split, down from prior levels above 5%.
  • The 1-for-80 reverse stock split became effective September 10, 2026, as disclosed in the issuer's 8-K filed September 9, 2026.
  • Valence and Cogence maintain open short positions referencing 44,364 and 2,290 common shares, respectively.
  • The filing reports continuous net selling of shares from July through September 2026, with post-split sales at prices between $10.39 and $12.30 per share.
  • A D. E. Shaw-aligned director, Gregory A. Ciongoli (founder of Adiumentum Capital Management), was appointed to the board on September 16, 2026.

Financial Impact

D. E. Shaw reduced its stake below the 5% threshold and maintains disclosed short positions, signaling reduced conviction. Post-split share sales occurred at $10.39-$12.30 per share.

ownership percentageshort interest

Risk Factors

  • D. E. Shaw may continue to reduce its position, adding selling pressure.
  • The disclosed short positions create a conflict of interest that could lead to negative sentiment or regulatory scrutiny.
  • The reverse stock split and activist exit could signal underlying business challenges.

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 7 SEC documents filed with EDGAR.

DocumentAccession Number
SC 13D/A Filing (Primary)0001104659-26-111463
Document: tm2626520d1_ex99-4.htm0001104659-26-111463
Document: tm2626520d1_ex99-2.htm0001104659-26-111463
Document: tm2626520d1_ex99-3.htm0001104659-26-111463
Document: 0001104659-26-111463-index-headers.html0001104659-26-111463
Document: 0001104659-26-111463-index.html0001104659-26-111463
Document: 0001104659-26-111463.txt0001104659-26-111463
15 reports for GOSS
Performance horizon
75% Hit rate @ T+20 3 of 4 directional calls Went positive at some point 5 of 5 best @ T+60▲ +25.28%Jun 17, 2026
Filters
Rows
Reports for GOSS — sortable, filterable
TypeNow
Oct 8, 2026
17d ago
SC 13D/A
BEARISH ★ 5/10
$9.31awaiting T+20—$9.41 (−1.07%)
Sep 28, 2026
27d ago
SC 13D/A
BEARISH ★ 6/10
$11.58awaiting T+20—$9.41 (+18.74%)
Sep 22, 2026
4w ago
Institutional Cluster
MIXED ★ 4/10
$11.69 $9.58▼ −18.05%▼ −17.49%$9.41 (−19.50%)
Sep 16, 2026
5w ago
8-K
NEUTRAL ★ 4/10
$11.94 $8.89▼ −25.54%▼ −26.75%$9.41 (−21.19%)
Sep 11, 2026
6w ago
8-K
BEARISH ★ 6/10
$10.73 $9.31▲ +13.23%▲ +15.10%$9.41 (+12.30%)
Sep 9, 2026
6w ago
8-K
NEUTRAL ★ 3/10
$0.1597 $0.1273▼ −20.32%▼ −22.26%$9.41 (+5792.30%)
Aug 21, 2026
9w ago
8-K
BEARISH ★ 6/10
$0.1547 $0.1410▲ +8.86%▲ +9.87%$9.41 (−5982.74%)
Aug 13, 2026
10w ago
8-K
NEUTRAL ★ 5/10
$0.1542 $0.1337▼ −13.26%▼ −11.27%$9.41 (+6002.46%)
Jul 1, 2026
16w ago
8-K
BEARISH ★ 5/10
$0.1677 $0.1783▼ −6.32%▼ −6.87%$9.41 (−5511.21%)
Jun 17, 2026
18w ago
8-K
BEARISH ★ 7/10
$0.1790 $0.1701▲ +4.97%▲ +5.29%$9.41 (−5156.98%)
Showing 10 of 15

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Report published Sep 28, 2026