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Institutional Cluster ·Filed Sep 22, 2026

GOSS

Gossamer Bio, Inc.
MIXED
Impact 4/10
Horizonweeks Processed1mo ago
Institutional cluster: 32 buyers, 17 sellers (mixed)
Actionable Insight ◆ Mixed

The aggressive accumulation by quant funds (D.E. Shaw, RenTech, Millennium) at very low absolute dollar values suggests a high-risk, binary-event thesis (e.g., upcoming clinical trial readout or partnership). The simultaneous reduction by passive/index funds indicates no fundamental catalyst has yet materialized. Monitor for a press release or 8-K regarding pipeline updates, as the quant positioning may front-run a catalyst.

DirectionMixed
Confidencemedium
Horizonweeks
Latest settled — T+20d
GOSS ▼ -18.05% at T+20d
NEUTRAL call -18.05% · α vs SPY -17.49% · entry $11.69 → $9.58
Next anchor: T+60d in 7w
Latest observation: T+23 -7.92% FF3 residual α
Entry = T+0 close
Sep 22, 2026
via day close
T+1d
-5.99%
call -5.99% · α -5.27%
$10.99
settled 5w ago
T+5d
-0.94%
call -0.94% · α +0.25%
$11.58
settled 28d ago
T+20d
-18.05%
call -18.05% · α -17.49%
$9.58
settled 7d ago
T+60d
Pending
in 7w

Executive Summary

In Q2 2026, a cluster of 32 institutional buyers accumulated $8.5M in Gossamer Bio (GOSS) while 17 sellers reduced holdings by $3.8M, resulting in net buying of $4.7M. The buying was dominated by quant funds (RenTech, D.E. Shaw, Millennium) making massive position increases, while selling was concentrated among mega-passive managers (Geode, BofA, Northern Trust) trimming or nearly exiting. The divergence between active quant accumulation and passive index fund reduction suggests a speculative thesis around a binary catalyst (e.g., clinical data readout) rather than fundamental improvement.

Key Financial Metrics

Direction
mixed
Buy Value
$10.0M
Sell Value
$3.8M
Net Flow
$4.7M

Institutional Positions

Net institutional flow: $4.7M

▲ Buyers (32)

InstitutionActionChangePosition ValueValue Δ
D.E. ShawDOUBLED+10417.7%$6.7M$6.6M
RenTechDOUBLED+854.9%$1.9M$1.5M
MillenniumDOUBLED+1182%$395.0K$334.0K
UBSADD+64.2%$510.0K-$109.0K

▼ Sellers (17)

InstitutionActionChangePrev ValueValue Δ
GeodeTRIM-49.8%$1.6M-$1.2M
BofANEAR_EXIT-87.5%$1.0M-$976.0K
Northern TrustTRIM-67.5%$463.0K-$387.0K
SchwabTRIM-34.3%$496.0K-$333.0K
Vanguard Portfolio ManagementTRIM-74.8%$711.0K-$621.0K

Key Facts

  • 32 institutional buyers added $8.5M in new positions; 17 sellers reduced by $3.8M
  • D.E. Shaw increased its stake by 10,417% (389K → 40.96M shares, value $128K → $6.7M)
  • RenTech more than 9x'd its position (1.22M → 11.63M shares, value $400K → $1.9M)
  • Millennium increased by 1,182% (187K → 2.40M shares, value $62K → $395K)
  • Geode cut its position by 49.8% (4.94M → 2.48M shares, value $1.6M → $409K)
  • BofA nearly exited, reducing by 87.5% (3.17M → 396.7K shares, value $1.0M → $65K)
  • Vanguard Portfolio Management trimmed by 74.8% (2.16M → 544.2K shares, value $711K → $90K)

Financial Impact

Net institutional buying of approximately $4.7M in Q2 2026, with quant funds adding $8.4M and passive/index funds reducing by $3.0M

institutional ownershipfloat concentration

Risk Factors

  • 13F data is 45 days stale; positions may have already been reversed
  • Quant funds often trade on short-term signals and may exit quickly
  • Passive fund selling suggests no broad-based institutional conviction
  • GOSS is a micro-cap biotech with high binary risk; small dollar amounts indicate low conviction even among buyers

Investment Themes

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-GOSS-2026-Q2
15 reports for GOSS
Performance horizon
75% Hit rate @ T+20 3 of 4 directional calls Went positive at some point 6 of 6 best @ T+60▲ +25.28%Jun 17, 2026
Filters
Rows
Reports for GOSS — sortable, filterable
TypeNow
Oct 8, 2026
18d ago
SC 13D/A
BEARISH ★ 5/10
$9.31awaiting T+20——
Sep 28, 2026
28d ago
SC 13D/A
BEARISH ★ 6/10
$11.58awaiting T+20——
Sep 22, 2026
4w ago
Institutional Cluster
MIXED ★ 4/10
$11.69 $9.58▼ −18.05%▼ −17.49%—
Sep 16, 2026
5w ago
8-K
NEUTRAL ★ 4/10
$11.94 $8.89▼ −25.54%▼ −26.75%—
Sep 11, 2026
6w ago
8-K
BEARISH ★ 6/10
$10.73 $9.31▲ +13.23%▲ +15.10%—
Sep 9, 2026
6w ago
8-K
NEUTRAL ★ 3/10
$0.1597 $0.1273▼ −20.32%▼ −22.26%—
Aug 21, 2026
9w ago
8-K
BEARISH ★ 6/10
$0.1547 $0.1410▲ +8.86%▲ +9.87%—
Aug 13, 2026
10w ago
8-K
NEUTRAL ★ 5/10
$0.1542 $0.1337▼ −13.26%▼ −11.27%—
Jul 1, 2026
16w ago
8-K
BEARISH ★ 5/10
$0.1677 $0.1783▼ −6.32%▼ −6.87%—
Jun 17, 2026
18w ago
8-K
BEARISH ★ 7/10
$0.1790 $0.1701▲ +4.97%▲ +5.29%—
Showing 10 of 15

US Market Status

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Report published Sep 22, 2026