Institutional Cluster

FULC

Fulcrum Therapeutics, Inc.
MIXED
Impact 5/10
Horizonweeks Processed3mo ago
Institutional cluster: 5 buyers, 4 sellers (mixed)
Actionable Insight ◆ Mixed

The divergence between aggressive quant buying (Point72, D.E. Shaw) and near-exits by RenTech and AllianceBernstein creates a high-conviction tug-of-war. Monitor for a near-term catalyst (e.g., pipeline update or earnings) that could resolve the thesis — the quant buyers may be positioning for a binary event. Given the poor historical T+20 returns on FULC reports, avoid front-running this cluster without a specific catalyst trigger.

DirectionMixed
Confidencemedium
Horizonweeks
Final — all horizons settled through T+60d
FULC ▲ +8.45% at T+60d
NEUTRAL call ✓ call won +8.45% · α vs SPY +4.05% · entry $3.55 → $3.85
Entry anchored
Jun 11, 01:30 PM ET
via exchange tick
T+1d
-2.82%
call -2.82% · α -3.36%
$3.45
settled 4mo ago
T+5d
-1.41%
call -1.41% · α -1.84%
$3.50
settled 4mo ago
T+20d
+1.13%
call +1.13% · α -0.76%
$3.59
settled 3mo ago
T+60d
+8.45%
call +8.45% · α +4.05%
$3.85
settled 24d ago

Executive Summary

A mixed institutional cluster in FULC for Q4 2025 shows $41.9M in net buying concentrated in two new/large quant positions (Point72 NEW $27.1M, D.E. Shaw ADD $8.3M) offset by $3.0M in selling from four firms, including near-exits by RenTech and AllianceBernstein. The cluster is dominated by active quant funds on the buy side, suggesting a catalyst-driven thesis, but the historical calibration on FULC reports shows a -7.33% average T+20 return with only 20% win rate, indicating the stock has not rewarded institutional conviction in recent quarters.

Key Financial Metrics

Direction
mixed
Buy Value
$58.0M
Sell Value
$3.0M
Net Flow
$38.9M

Institutional Positions

Net institutional flow: $38.9M

▲ Buyers (5)

InstitutionActionChangePosition ValueValue Δ
Point72NEW+0%$27.1M$27.1M
D.E. ShawADD+32%$21.6M$8.3M
InvescoDOUBLED+236.8%$4.7M$3.6M
Wells FargoDOUBLED+411.9%$1.9M$1.6M
BofAADD+57%$2.6M$1.3M

▼ Sellers (4)

InstitutionActionChangePrev ValueValue Δ
RenTechNEAR_EXIT-93%$2.3M-$2.1M
AllianceBernsteinNEAR_EXIT-79.5%$686.0K-$513.5K
Morgan StanleyTRIM-32.1%$2.2M-$370.1K
Franklin ResourcesTRIM-26.3%$552.0K-$51.7K

Key Facts

  • 5 buyers accumulated $41.9M net, led by Point72 (NEW $27.1M) and D.E. Shaw (ADD $8.3M)
  • 4 sellers reduced holdings by $3.0M, including RenTech near-exit (-93% shares) and AllianceBernstein near-exit (-79.5%)
  • Buy-side is dominated by active quant funds (Point72, D.E. Shaw); sell-side includes two asset managers (Franklin, AllianceBernstein) and one quant (RenTech)
  • Mega-passive buyers (BofA, Wells Fargo, Invesco) added small positions totaling $6.5M, likely index-rebalancing noise
  • Historical reports on FULC show poor T+20 performance (-7.33% avg return, 20% win rate), suggesting the stock has been a value trap

Financial Impact

5 institutions accumulated $58.0M in current holdings (net change +$41.9M) while 4 institutions reduced holdings by $3.0M, for a net institutional inflow of approximately $38.9M

institutional ownershipfloat turnover

Risk Factors

  • RenTech and AllianceBernstein near-exits suggest informed selling by historically successful quant/asset managers
  • Historical FULC reports show -7.33% average T+20 return and 20% win rate — institutional clusters have not been predictive
  • Point72's $27.1M new position is large for a $234M market cap (11.6% of float) and could create overhang if unwound

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
81% bullish (16 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-FULC-2025-Q4
11 reports for FULC
Performance horizon
100% Hit rate 6 of 6 directional calls best @ T+5▲ +7.43%Jul 15, 2026
Filters
Rows
Reports for FULC — sortable, filterable
TypeNow
Sep 2, 2026
4w ago
S-4
BEARISH ★ 7/10
$3.85 $3.70▲ +3.90%▲ +3.57%—
Aug 17, 2026
6w ago
425
BEARISH ★ 7/10
$3.84 $3.78▲ +1.56%▼ −0.42%—
Aug 17, 2026
6w ago
425
BULLISH ★ 8/10
$3.84 $3.78▼ −1.56%▲ +0.42%—
Aug 17, 2026
6w ago
8-K
BULLISH ★ 8/10
$3.84 $3.78▼ −1.56%▲ +0.42%—
Aug 17, 2026
6w ago
Press Release
BULLISH ★ 8/10
$3.84 $3.78▼ −1.56%▲ +0.42%—
Aug 10, 2026
7w ago
8-K
NEUTRAL ★ 2/10
$3.75 $3.82▲ +1.87%▲ +2.78%—
Jul 15, 2026
11w ago
3
BULLISH ★ 6/10
$3.50 $3.71▲ +6.00%▲ +2.38%—
Jun 11, 2026
16w ago
Institutional Cluster
MIXED ★ 5/10
$3.55 $3.59▲ +1.13%▼ −0.76%—
Apr 27, 2026
22w ago
8-K
MIXED ★ 6/10
$7.72 $6.76▼ −12.44%▼ −17.39%—
Apr 27, 2026
22w ago
Press Release
MIXED ★ 6/10
$7.72 $6.76▼ −12.44%▼ −17.39%—
Showing 10 of 11

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Report published Jun 11, 2026