Institutional Cluster

ESPR

Esperion Therapeutics, Inc.
MIXED
Impact 4/10
Horizonweeks Processed3mo ago
Institutional cluster: 4 buyers, 2 sellers (mixed)
Actionable Insight ◆ Mixed

The strong buying from active quant (RenTech) and asset manager (Nuveen) funds signals conviction in Esperion's near-term prospects, but the 45-day 13F lag means positions may already be stale. Watch for Q4 2025 13F filings to see if these adds were maintained or reversed, and monitor upcoming earnings for revenue trajectory on NEXLETOL/NEXLIZET.

DirectionMixed
Confidencemedium
Horizonweeks
Latest settled — T+20d
ESPR ▲ +1.27% at T+20d
NEUTRAL call ✓ call won +1.27% · α vs SPY -0.62% · entry $3.15 → $3.19
Next anchor: T+60d due 24d ago
Entry anchored
Jun 11, 03:24 PM ET
via exchange tick
T+1d
0.00%
call 0.00% · α -0.54%
$3.15
settled 4mo ago
T+5d
+0.63%
call +0.63% · α +0.20%
$3.17
settled 4mo ago
T+20d
+1.27%
call +1.27% · α -0.62%
$3.19
settled 3mo ago
T+60d
—
call — · α —
—
due 24d ago

Executive Summary

Four institutional investors added $22.0M in ESPR positions during Q3 2025, led by Morgan Stanley and Nuveen doubling their stakes, while Citadel and BofA trimmed $1.7M. The cluster is mixed but dominated by active buying from quant and asset-manager funds, suggesting a shared thesis around Esperion's commercial execution or pipeline catalysts, though the 45-day reporting lag means positions may have shifted since quarter-end.

Key Financial Metrics

Direction
accumulating
Buy Value
$24.3M
Sell Value
$1.7M
Net Flow
$20.3M

Institutional Positions

Net institutional flow: $20.3M

▲ Buyers (4)

InstitutionActionChangePosition ValueValue Δ
Morgan StanleyDOUBLED+284.2%$10.7M$9.7M
NuveenDOUBLED+778.1%$9.8M$9.4M
RenTechDOUBLED+164.7%$2.1M$1.8M
InvescoADD+25.5%$1.6M$1.2M

▼ Sellers (2)

InstitutionActionChangePrev ValueValue Δ
CitadelTRIM-34.3%$2.3M$1.8M
BofATRIM-63.6%$823.0K-$15.8K

Key Facts

  • 4 buyers added $22.0M in net new positions; 2 sellers reduced by $1.7M
  • Morgan Stanley doubled its stake (+284.2%) to $10.7M; Nuveen nearly 8x'd to $9.8M
  • RenTech doubled (+164.7%) to $2.1M; Invesco added 25.5% to $1.6M
  • Citadel trimmed 34.3% but still holds $4.1M; BofA cut 63.6% to $807K
  • Active managers (Nuveen, RenTech) dominate the buying side; passive funds (Morgan Stanley, Invesco) also added

Financial Impact

4 institutions accumulated $22.0M in new positions while 2 reduced holdings by $1.7M, net institutional inflow of ~$20.3M

institutional ownershipfloat demand

Risk Factors

  • 13F data is 45+ days stale; positions may have been unwound since quarter-end
  • Analyst consensus is 0% bullish (8 Hold, 3 Sell/Strong Sell) — institutional buying is contrarian to Street sentiment
  • Historical calibration shows score-4/5 reports on ESPR have mixed T+20 outcomes; past high-score calls (7-8) underperformed

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
0% bullish (11 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-ESPR-2025-Q3
20 reports for ESPR
Performance horizon
75% Hit rate 6 of 8 directional calls best @ T+60▲ +16.30%Mar 10, 2026
Filters
Rows
Reports for ESPR — sortable, filterable
TypeNow
Sep 3, 2026
29d ago
Court Ruling
BULLISH ★ 5/10
—awaiting T+5——
Aug 13, 2026
7w ago
Institutional Cluster
BEARISH ★ 5/10
—awaiting T+5——
Jul 23, 2026
10w ago
15-12G
NEUTRAL ★ 5/10
—awaiting T+5——
Jul 16, 2026
11w ago
EFFECT
BEARISH ★ 5/10
$3.18 awaiting T+5awaiting T+5——
Jul 16, 2026
11w ago
EFFECT
BEARISH ★ 5/10
$3.18 awaiting T+5awaiting T+5——
Jul 13, 2026
11w ago
25-NSE
BULLISH ★ 7/10
$3.19 awaiting T+5awaiting T+5——
Jul 13, 2026
11w ago
8-K
BULLISH ★ 7/10
$3.19 awaiting T+5awaiting T+5——
Jun 16, 2026
15w ago
DEFA14A
BULLISH ★ 6/10
$3.17 $3.15▼ −0.63%▲ +0.41%—
Jun 11, 2026
16w ago
Institutional Cluster
MIXED ★ 4/10
$3.15 $3.17▲ +0.63%▲ +0.20%—
Jun 9, 2026
16w ago
8-K
BULLISH ★ 6/10
$3.14 $3.16▲ +0.64%▼ −2.80%—
Showing 10 of 20

US Market Status

Market Closed — Opens Mon (64h 9m)

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Report published Jun 11, 2026