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Institutional Cluster

CSTL

CASTLE BIOSCIENCES INC
BEARISH
Impact 5/10
Horizonweeks Processed4mo ago
Institutional cluster: 2 buyers, 5 sellers (bearish)
Actionable Insight ▼ Bearish

Institutional cluster shows significant net selling led by quantitative funds (Citadel, D.E. Shaw). Despite bullish analyst consensus, this selling pressure flags potential near-term weakness. Monitor for further insider activity or guidance changes.

DirectionBearish
Confidencemedium
Horizonweeks
Final — all horizons settled through T+60d
CSTL ▲ +56.64% at T+60d
SHORT call ✗ call lost -56.64% · α vs SPY -52.24% · entry $21.01 → $32.91
Entry = T+0 close
Jun 11, 2026
via day close
T+1d
-1.48%
call +1.48% · α +2.02%
$20.70
settled 5mo ago
T+5d
-3.62%
call +3.62% · α +4.05%
$20.25
settled 4mo ago
T+20d
+16.90%
call -16.90% · α -15.01%
$24.56
settled 4mo ago
T+60d
+56.64%
call -56.64% · α -52.24%
$32.91
settled 7w ago

Executive Summary

Institutional cluster for CSTL reveals 5 sellers (notably Citadel trimming 71.8% of its stake) vs 2 passive buyers, resulting in net selling of ~$11M. Quant funds leading the exit suggests caution despite bullish analyst sentiment.

Key Financial Metrics

Direction
distributing
Buy Value
$7.4M
Sell Value
$30.8M
Net Flow
-$11.0M

Institutional Positions

Net institutional flow: -$11.0M

▲ Buyers (2)

InstitutionActionChangePosition ValueValue Δ
Morgan StanleyADD+60.9%$6.1M$2.7M
InvescoADD+38.1%$1.3M$446.0K

▼ Sellers (5)

InstitutionActionChangePrev ValueValue Δ
D.E. ShawTRIM-37.5%$3.0M-$917.2K
CitadelTRIM-71.8%$18.1M-$12.4M
Ubs Am, A Distinct Business UnTRIM-44.1%$2.1M-$789.6K
Ameriprise FinancialTRIM-31.2%$7.6M-$1.8M
BarclaysTRIM-33.4%$2.0K$1.7M

Key Facts

  • 5 institutions reduced positions by $14.2M while 2 passive funds added $3.2M
  • Net institutional selling of approximately $11.0M
  • Citadel cut 71.8% of its stake, selling $12.4M worth
  • D.E. Shaw reduced by 37.5%, selling $917K
  • Only passive buyers (Morgan Stanley, Invesco) added shares

Financial Impact

5 institutions reduced holdings by $14.2M while 2 passive funds added $3.2M, resulting in net institutional selling of approximately $11.0M.

institutional ownershipsentiment

Risk Factors

  • 13F data is 45+ days stale; positions may have been unwound further
  • Passive buying could offset selling pressure
  • Strong analyst consensus may be overoptimistic

Market Snapshot

Exchange
Nasdaq
Sector
Services-Medical Laboratories
Analyst Consensus
93% bullish (14 analysts)

Investment Themes

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-CSTL-2025-Q3
31 reports for CSTL
Performance horizon
56% Hit rate @ T+1 5 of 9 directional calls Went positive at some point 8 of 9 best @ T+60▲ +27.32%Mar 5, 2026
Filters
Rows
Reports for CSTL — sortable, filterable
TypeNow
Oct 21, 2026
5d ago
Insider Cluster
NEUTRAL ★ 3/10
$33.19 $33.08▼ −0.33%▲ +0.19%—
Oct 5, 2026
21d ago
144
NEUTRAL ★ 4/10
$33.36 $33.00▼ −1.08%▼ −0.84%—
Oct 5, 2026
21d ago
Insider Cluster
NEUTRAL ★ 2/10
$33.36 $33.00▼ −1.08%▼ −0.84%—
Sep 23, 2026
4w ago
Insider Cluster
BEARISH ★ 4/10
$35.19 $35.81▼ −1.76%▼ −1.22%—
Sep 16, 2026
5w ago
Insider Cluster
NEUTRAL ★ 2/10
$36.78 $35.34▼ −3.92%▼ −4.04%—
Sep 11, 2026
6w ago
144
NEUTRAL ★ 4/10
$33.44 $35.50▲ +6.16%▲ +6.62%—
Sep 3, 2026
7w ago
Insider Cluster
BEARISH ★ 4/10
$32.91 $32.76▲ +0.46%▼ −0.09%—
Sep 2, 2026
7w ago
Insider Cluster
NEUTRAL ★ 2/10
$32.65 $32.91▲ +0.80%▲ +1.18%—
Sep 1, 2026
7w ago
Insider Cluster
NEUTRAL ★ 2/10
$33.42 $32.65▼ −2.30%▼ −3.35%—
Aug 27, 2026
8w ago
Insider Cluster
NEUTRAL ★ 4/10
$33.50 $33.03▼ −1.40%▼ −1.10%—
Showing 10 of 31

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Report published Jun 11, 2026