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Insider Cluster (2 insiders) ·Filed Sep 23, 2026

CSTL

CASTLE BIOSCIENCES INC
BEARISH
Impact 4/10
Horizonweeks Processed1mo ago
Insider cluster: 2 insiders, $419K total
Actionable Insight ▼ Bearish

The CEO and CCO both sold shares in a tight window without a disclosed trading plan, which is unusual for a biotech with potential binary catalysts. Monitor for upcoming news (data readouts, regulatory updates) that may have prompted the sales. If the stock drifts lower, the selling could accelerate.

DirectionBearish
Confidencemedium
Horizonweeks
Latest settled — T+20d
CSTL ▼ -5.68% at T+20d
SHORT call ✓ call won +5.68% · α vs SPY +5.26% · entry $35.19 → $33.19
Next anchor: T+60d in 7w
Latest observation: T+21 +16.62% FF3 residual α
Entry = T+0 close
Sep 24, 2026
via day close
T+1d
+1.76%
call -1.76% · α -1.22%
$35.81
settled 5w ago
T+5d
+0.18%
call -0.18% · α -0.60%
$35.26
settled 26d ago
T+20d
-5.68%
call +5.68% · α +5.26%
$33.19
settled 5d ago
T+60d
Pending
in 7w

Price Chart

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Executive Summary

CEO Derek Maetzold and CCO Tobin Juvenal sold a combined $419K in open-market sales over a one-week window. The total represents ~0.13% of market cap, a modest but notable insider sale cluster. No 10b5-1 plan is indicated, and the sales are not routine vesting or tax-withholding transactions.

Key Financial Metrics

Direction
selling
Total Value
$419.0K
Insiders
2

Key Facts

  • CEO Derek Maetzold sold 8.6K shares at $35.33 for $303K on 2026-09-21
  • CCO Tobin Juvenal sold 3.3K shares at $35.14 for $116K on 2026-09-15
  • Total insider sales: $419K, representing ~0.13% of market cap
  • Both sales are open-market (code S) with no 10b5-1 plan indication
  • Cluster involves two C-suite executives selling within a 6-day window

Financial Impact

Insider sales of $419K, ~0.13% of market cap

insider ownership

Risk Factors

  • Insider sales may signal management's lack of confidence in near-term catalysts
  • No 10b5-1 plan increases the likelihood of opportunistic selling
  • Cluster selling by two C-suite executives is more informative than a single sale

Investment Themes

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-CSTL-1790231064236
31 reports for CSTL
Performance horizon
67% Hit rate @ T+1 6 of 9 directional calls Went positive at some point 8 of 9 best @ T+60▲ +27.32%Mar 5, 2026
Filters
Rows
Reports for CSTL — sortable, filterable
TypeNow
Oct 21, 2026
5d ago
Insider Cluster
NEUTRAL ★ 3/10
$33.19 $33.08▼ −0.33%▲ +0.19%$33.30 (+0.33%)
Oct 5, 2026
21d ago
144
NEUTRAL ★ 4/10
$33.36 $33.00▼ −1.08%▼ −0.84%$33.30 (−0.18%)
Oct 5, 2026
21d ago
Insider Cluster
NEUTRAL ★ 2/10
$33.36 $33.00▼ −1.08%▼ −0.84%$33.30 (−0.18%)
Sep 23, 2026
4w ago
Insider Cluster
BEARISH ★ 4/10
$35.19 $35.81▼ −1.76%▼ −1.22%$33.30 (+5.37%)
Sep 16, 2026
5w ago
Insider Cluster
NEUTRAL ★ 2/10
$36.78 $35.34▼ −3.92%▼ −4.04%$33.30 (−9.46%)
Sep 11, 2026
6w ago
144
NEUTRAL ★ 4/10
$33.44 $35.50▲ +6.16%▲ +6.62%$33.30 (−0.42%)
Sep 3, 2026
7w ago
Insider Cluster
BEARISH ★ 4/10
$32.91 $32.76▲ +0.46%▼ −0.09%$33.30 (−1.19%)
Sep 2, 2026
7w ago
Insider Cluster
NEUTRAL ★ 2/10
$32.65 $32.91▲ +0.80%▲ +1.18%$33.30 (+1.99%)
Sep 1, 2026
7w ago
Insider Cluster
NEUTRAL ★ 2/10
$33.42 $32.65▼ −2.30%▼ −3.35%$33.30 (−0.36%)
Aug 27, 2026
8w ago
Insider Cluster
NEUTRAL ★ 4/10
$33.50 $33.03▼ −1.40%▼ −1.10%$33.30 (−0.60%)
Showing 10 of 31

US Market Status

Market Closed — Opens in 6h 34m

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Report published Sep 23, 2026