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144 ·Filed Oct 5, 2026

CSTL

CASTLE BIOSCIENCES INC
NEUTRAL
Impact 4/10
Horizonweeks Processed21d 8h ago SEC0001958244-26-000640
Form 144 — notice of proposed sale of securities
Actionable Insight • Neutral

The filing confirms the CEO is actively selling under a pre-arranged plan, not a discretionary sale. The plan was adopted months before the filing date, so the sale is not a reaction to recent events. Monitor for any subsequent Form 4 filings to see if the sale is executed, and watch for any changes in the company's guidance or earnings outlook.

DirectionNeutral
Confidencemedium
Horizonweeks
Latest settled — T+5d
CSTL ▼ -1.44% at T+5d
NEUTRAL call -1.44% · α vs SPY -1.30% · entry $33.36 → $32.88
Next anchor: T+20d in 6d
Latest observation: T+13 -6.64% FF3 residual α
Entry = T+0 close
Oct 5, 2026
via day close
T+1d
-1.08%
call -1.08% · α -0.84%
$33.00
settled 21d ago
T+5d
-1.44%
call -1.44% · α -1.30%
$32.88
settled 15d ago
T+20d
Pending
in 6d
T+60d
Pending
in 2mo

Price Chart

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Executive Summary

CEO Derek Maetzold filed a Form 144 notice of intent to sell 28,992 shares of Castle Biosciences common stock, with an estimated aggregate market value of approximately $1,062,557 as of October 5, 2026. The sales are part of a Rule 10b5-1 trading plan adopted on June 2, 2026, covering shares held directly and through trusts. While the CEO's planned sale is notable, the pre-arranged plan structure reduces the signaling concern of a discretionary insider sale.

Key Facts

  • CEO Derek Maetzold filed Form 144 to sell 28,992 shares of common stock.
  • Estimated aggregate market value of the proposed sale is approximately $1,062,557.
  • Sales are being made pursuant to a Rule 10b5-1 trading plan dated June 2, 2026.
  • Shares are to be sold through Goldman Sachs & Co. LLC on behalf of Derek Maetzold.
  • The plan covers shares held directly by Derek Maetzold (17,160 shares), the DM 2020 Irrevocable Trust (5,436 shares), and the Maetzold Descendants 2020 Trust (5,396 shares).
  • The filing date is October 5, 2026.
  • The plan was adopted on June 2, 2026.
  • The filing includes a large number of prior sales from July through September 2026, indicating a pattern of consistent selling under the plan.

Financial Impact

CEO's proposed sale of ~$1.06M worth of shares is a moderate proportion of his holdings, but the 10b5-1 plan structure reduces the typical insider signal. The total number of shares to be sold is 28,992 shares.

dilutioninsider selling

Risk Factors

  • CEO selling under a 10b5-1 plan reduces the signal of a discretionary insider sale.
  • The plan was adopted months before the filing date, so the sale is not a reaction to recent events.
  • The filing includes a large number of prior sales from July through September 2026, indicating a pattern of consistent selling under the plan.

Investment Themes

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
144 Filing (Primary)0001958244-26-000640
Document: 0001958244-26-000640-index.html0001958244-26-000640
Document: 0001958244-26-000640.txt0001958244-26-000640
31 reports for CSTL
Performance horizon
60% Hit rate @ T+1 6 of 10 directional calls Went positive at some point 9 of 10 best @ T+60▲ +27.32%Mar 5, 2026
Filters
Rows
Reports for CSTL — sortable, filterable
TypeNow
Oct 21, 2026
5d ago
Insider Cluster
NEUTRAL ★ 3/10
$33.19 $33.08▼ −0.33%▲ +0.19%$33.30 (+0.33%)
Oct 5, 2026
21d ago
144
NEUTRAL ★ 4/10
$33.36 $33.00▼ −1.08%▼ −0.84%$33.30 (−0.18%)
Oct 5, 2026
21d ago
Insider Cluster
NEUTRAL ★ 2/10
$33.36 $33.00▼ −1.08%▼ −0.84%$33.30 (−0.18%)
Sep 23, 2026
4w ago
Insider Cluster
BEARISH ★ 4/10
$35.19 $35.81▼ −1.76%▼ −1.22%$33.30 (+5.37%)
Sep 16, 2026
5w ago
Insider Cluster
NEUTRAL ★ 2/10
$36.78 $35.34▼ −3.92%▼ −4.04%$33.30 (−9.46%)
Sep 11, 2026
6w ago
144
NEUTRAL ★ 4/10
$33.44 $35.50▲ +6.16%▲ +6.62%$33.30 (−0.42%)
Sep 3, 2026
7w ago
Insider Cluster
BEARISH ★ 4/10
$32.91 $32.76▲ +0.46%▼ −0.09%$33.30 (−1.19%)
Sep 2, 2026
7w ago
Insider Cluster
NEUTRAL ★ 2/10
$32.65 $32.91▲ +0.80%▲ +1.18%$33.30 (+1.99%)
Sep 1, 2026
7w ago
Insider Cluster
NEUTRAL ★ 2/10
$33.42 $32.65▼ −2.30%▼ −3.35%$33.30 (−0.36%)
Aug 27, 2026
8w ago
Insider Cluster
NEUTRAL ★ 4/10
$33.50 $33.03▼ −1.40%▼ −1.10%$33.30 (−0.60%)
Showing 10 of 31

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Report published Oct 5, 2026