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PRESS-RELEASE ·Filed Nov 2, 2026

CRSP

CRISPR Therapeutics AG
MIXED
Impact 5/10
Horizondays Processed5d 21h ago WireGlobeNewswire
Press release · Earnings
Actionable Insight ◆ Mixed

Monitor upcoming Phase 1b data for CTX310 at AHA on Nov 9 and Phase 1 data for zugo-cel at ACR on Nov 8. CASGEVY revenue trajectory and pipeline catalysts are key near-term drivers.

DirectionMixed
Confidencehigh
Horizondays

How the stock moved after the report

⚠ Clustered NEUTRAL VIEWSTOCK ABOVE ENTRY AT T+1
Entry
$49.99
T+0 close · Nov 2, 2026 · via day close
Latest settled
+3.57%
T+1 · $51.78
vs SPY
+1.92%
α at T+1
Next horizon
T+5
in 17h
  1. T+0 · Nov 2 $49.99entry
  2. T+1 · 5d ago +3.57%α +1.92% · $51.78
  3. T+4 · todayOpen
  4. T+5 · in 17h Pending
  5. T+20 · in 23d Pending
  6. T+60 · in 3mo Pending
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Executive Summary

CRISPR Therapeutics reported Q3 2026 CASGEVY revenue of $99 million, up 30% quarter-over-quarter and nearly 6x year-over-year, but total revenue of $12.7 million (collaboration + grant) missed the $16.6 million consensus. Net loss per share was -$1.15, wider than the consensus estimate of -$1.06, driven by higher R&D and acquired IPR&D expenses. The CASGEVY growth and pipeline progress are offset by the EPS miss and revenue shortfall.

Key Financial Metrics

EPS
−$1.15
est −$1.06 · -8.5%
Revenue
$12.7M
est $16.6M · -23.7%
Rating
miss

Key Facts

  • CASGEVY revenue of $99 million in Q3 2026, up 30% QoQ and nearly 6x vs Q3 2025
  • Total revenue $12.7 million (collaboration $12.3M + grant $0.3M) vs consensus $16.6M
  • Net loss per share -$1.15 (GAAP diluted) vs consensus -$1.06
  • Net loss $111.4 million vs $106.4 million in Q3 2025
  • Cash, cash equivalents and marketable securities $2,276.6 million as of Sep 30, 2026
  • FDA granted RMAT designations to CTX310 for severe hypertriglyceridemia and elevated LDL-C
  • Completed enrollment in Phase 2 trial of CTX611 in total knee arthroplasty
  • Appointed new CTO and CFO during the quarter

Financial Impact

CASGEVY revenue $99M; total revenue $12.7M vs $16.6M consensus; EPS -$1.15 vs -$1.06 consensus; net loss $111.4M

revenueepsnet losscash position

Risk Factors

  • Revenue miss vs consensus despite strong CASGEVY growth
  • EPS miss driven by higher R&D and acquired IPR&D expenses
  • Dependence on CASGEVY commercial ramp and regulatory approvals for younger patients
  • Pipeline programs still in early to mid-stage clinical development

Market Snapshot

Exchange
Nasdaq
Sector
Biological Products, (No Diagnostic Substances)
Analyst Consensus
59% bullish (29 analysts)

Investment Themes

Documents Analyzed

This report is based on 1 press release from GlobeNewswire.

DocumentAccession Number
PRESS-RELEASE Data (Synthetic)press-3393703
19 reports for CRSP
Performance horizon
75% Hit rate @ T+20 3 of 4 bullish or bearish reports Went positive at some point 5 of 6 best @ T+20▲ +8.92%Sep 24, 2026
Filters
Rows
Reports for CRSP, sortable and filterable
TypeNow
Nov 8, 2026
today
Press Release
NEUTRAL ★ 4/10
No priceawaiting T+20awaiting T+20No price
Nov 6, 2026
1d ago
144
NEUTRAL ★ 3/10
$48.98awaiting T+20awaiting T+20$50.07 (+2.23%)
Nov 2, 2026
5d ago
3
NEUTRAL ★ 1/10
$49.99awaiting T+20awaiting T+20$50.07 (+0.16%)
Nov 2, 2026
5d ago
8-K
NEUTRAL ★ 5/10
No priceawaiting T+20awaiting T+20No price
Nov 2, 2026
5d ago
Press Release
MIXED ★ 5/10
$49.99awaiting T+20awaiting T+20$50.07 (+0.16%)
Oct 20, 2026
18d ago
Insider Cluster
BEARISH ★ 5/10
$50.50awaiting T+20awaiting T+20$50.07 (+0.85%)
Oct 19, 2026
19d ago
8-K
NEUTRAL ★ 3/10
$49.88awaiting T+20awaiting T+20$50.07 (+0.38%)
Oct 16, 2026
22d ago
Insider Cluster
NEUTRAL ★ 3/10
$50.04awaiting T+20awaiting T+20$50.07 (+0.06%)
Oct 16, 2026
22d ago
Insider Cluster
BEARISH ★ 4/10
$50.04awaiting T+20awaiting T+20$50.07 (−0.06%)
Oct 15, 2026
23d ago
Insider Cluster
NEUTRAL ★ 3/10
$49.25awaiting T+20awaiting T+20$50.07 (+1.66%)
Showing 10 of 19

US Market Status

Market Closed · Opens Mon (19h 40m)

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Report published Nov 2, 2026