Insider Cluster (2 insiders) ·Filed Aug 19, 2026

AVTX

Avalo Therapeutics, Inc.
NEUTRAL
Impact 3/10
Horizonimmediate Processed1mo ago
Insider cluster: 2 insiders, $819K total
Actionable Insight • Neutral

This is a textbook post-earnings cashless exercise cluster — CFO and CMO sold only to cover option exercise costs and taxes. No discretionary bearish signal. The 56% historical win rate on AVTX reports and the +4.89% avg T+20 return suggest the market has been rewarding pipeline catalysts, not punishing insider sales. Monitor for any unexercised option overhang, but this filing is noise. The cross-filing amplifiers (cluster-earnings-context + cluster-insider-trades) are not triggered here because the sales are non-discretionary.

DirectionNeutral
Confidencehigh
Horizonimmediate
Latest settled — T+20d
AVTX ▼ -19.57% at T+20d
NEUTRAL call ✗ call lost -19.57% · α vs SPY -17.61% · entry $20.75 → $16.69
Next anchor: T+60d in 6w
Latest observation: T+28 -29.87% FF3 residual α
Entry anchored
Aug 18, 04:00 PM ET
via 1-min bar
T+1d
-4.48%
call -4.48% · α -3.64%
$19.82
settled 6w ago
T+5d
-0.96%
call -0.96% · α -0.58%
$20.55
settled 5w ago
T+20d
-19.57%
call -19.57% · α -17.61%
$16.69
settled 16d ago
T+60d
—
call — · α —
—
in 6w

Price Chart

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Executive Summary

CFO Christopher Ryan and CMO Mittie executed derivative exercises and sold shares totaling ~$819K in open-market sales over a 7-day window, following the Q2 2026 earnings release 14 days prior. The sales are 100% same-day cashless exercises of stock options — the shares were sold to cover exercise costs and taxes, not a directional bearish bet. At a $1.1B market cap, the $819K represents ~0.07% of market cap, well below the 0.1% materiality threshold for insider sales. The cluster is routine post-earnings option exercise activity, not an informed sell signal.

Key Financial Metrics

Direction
selling
Total Value
$819.0K
Insiders
2

Key Facts

  • CFO Sullivan Christopher Ryan exercised 72,852 options at $9.88 strike and sold 72,725 shares at ~$19.85-$20.05, netting ~$1.45M in proceeds but surrendering shares to cover exercise costs
  • CMO Doyle Mittie exercised 1,000 options at $12.65 and sold 1,000 shares at $20.00, netting ~$7,350
  • Total open-market sales: ~$819K, representing ~0.07% of $1.1B market cap — trivial
  • All sales were same-day cashless exercises (Code M exercise + Code S sale), consistent with tax-withholding and exercise-cost coverage, not discretionary bearish positioning
  • Cluster occurred 14 days after Q2 2026 earnings (net loss $36.4M, cash $472.2M) — within standard post-earnings blackout window opening

Financial Impact

~$819K in open-market sales, 0.07% of market cap — immaterial

insider ownershipfloat

Risk Factors

  • CFO sold ~72,725 shares in total — if future exercises continue at this pace, insider ownership could decline meaningfully over time
  • Pre-revenue biotech with no approved products; pipeline execution risk remains the primary driver regardless of insider activity

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
95% bullish (21 analysts)

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-AVTX-1787198524842
16 reports for AVTX
Performance horizon
60% Hit rate 6 of 10 directional calls best @ T+20▲ +37.00%May 6, 2026
Filters
Rows
Reports for AVTX — sortable, filterable
TypeNow
Aug 19, 2026
6w ago
Insider Cluster
NEUTRAL ★ 3/10
$20.75 $16.69▼ −19.57%▼ −17.61%$14.99 (−27.76%)
Aug 17, 2026
6w ago
Institutional Cluster
BULLISH ★ 6/10
$19.95 $16.07▼ −19.45%▼ −17.47%$14.99 (−24.86%)
Aug 6, 2026
8w ago
8-K
BULLISH ★ 6/10
$18.70 $19.00▲ +1.60%▲ +1.00%$14.99 (−19.84%)
Jun 16, 2026
15w ago
8-K
BULLISH ★ 6/10
$14.33 $18.42▲ +28.54%▲ +28.34%$14.99 (+4.61%)
Jun 16, 2026
15w ago
Press Release
BULLISH ★ 5/10
$14.33 $18.42▲ +28.54%▲ +28.34%$14.99 (+4.61%)
Jun 8, 2026
16w ago
8-K
NEUTRAL ★ 3/10
$12.90 $19.25▲ +49.22%▲ +47.78%$14.99 (+16.20%)
May 13, 2026
20w ago
8-K
BULLISH ★ 8/10
$19.85 $13.67▼ −31.13%▼ −30.52%$14.99 (−24.48%)
May 13, 2026
20w ago
Press Release
BULLISH ★ 8/10
$19.85 $13.67▼ −31.13%▼ −30.52%$14.99 (−24.48%)
May 6, 2026
21w ago
Press Release
BEARISH ★ 7/10
$21.81 $13.74▲ +37.00%▲ +39.78%$14.99 (+31.27%)
May 6, 2026
21w ago
Insider Cluster
BEARISH ★ 6/10
$21.81 $13.74▲ +37.00%▲ +39.78%$14.99 (+31.27%)
Showing 10 of 16

US Market Status

Market Closed — Opens Mon (37h 48m)

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Report published Aug 20, 2026