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Institutional Cluster ·Filed Sep 22, 2026

ATYR

aTYR PHARMA INC
BEARISH
Impact 4/10
Horizonweeks Processed1mo ago
Institutional cluster: 13 buyers, 15 sellers (mixed)
Actionable Insight ▼ Bearish

The overwhelming sell-side is driven by mega-passive funds (Fidelity, UBS, Geode, Northern Trust), which may reflect index rebalancing or risk-control triggers rather than a fundamental thesis break. However, the scale of Fidelity's near-exit ($10M) is unusual and warrants monitoring for any negative catalyst disclosure. The active/quants buying are small relative to the selling — not enough to offset the signal. Watch next 13F for continuation of the passive exodus.

DirectionBearish
Confidencemedium
Horizonweeks
Latest settled — T+20d
ATYR ▼ -51.37% at T+20d
SHORT call ✓ call won +51.37% · α vs SPY +50.81% · entry $0.3564 → $0.1733
Next anchor: T+60d in 7w
Latest observation: T+23 +39.51% FF3 residual α
Entry = T+0 close
Sep 22, 2026
via day close
T+1d
+5.28%
call -5.28% · α -6.00%
$0.3752
settled 5w ago
T+5d
-13.66%
call +13.66% · α +12.48%
$0.3077
settled 28d ago
T+20d
-51.37%
call +51.37% · α +50.81%
$0.1733
settled 7d ago
T+60d
Pending
in 7w

Executive Summary

Institutional activity in ATYR during Q2 2026 shows a stark divergence: mega-passive index funds (Fidelity, UBS, Geode, Northern Trust) aggressively reduced positions, with Fidelity alone cutting $10M (83% of its stake), while a handful of active managers and quants (Jane Street, Marshall Wace, RenTech) doubled small positions. The net dollar flow is heavily negative (-$14.7M selling vs +$1.5M buying), indicating broad institutional de-risking despite isolated accumulation by nimble players.

Key Financial Metrics

Direction
distributing
Buy Value
$1.9M
Sell Value
$14.7M
Net Flow
-$13.2M

Institutional Positions

Net institutional flow: -$13.2M

▲ Buyers (13)

InstitutionActionChangePosition ValueValue Δ
Jane Street GroupDOUBLED+3448.9%$1.0M$989.0K
Goldman SachsDOUBLED+126.4%$383.0K$162.0K
Marshall WaceDOUBLED+166.5%$221.0K$113.0K
RenTechDOUBLED+307.7%$99.0K$67.0K

▼ Sellers (15)

InstitutionActionChangePrev ValueValue Δ
FidelityNEAR_EXIT-83.2%$11.5M-$10.0M
UBSTRIM-60.4%$3.0M-$2.1M
GeodeTRIM-50.7%$1.9M-$1.2M
MillenniumTRIM-60%$1.3M-$889.0K
Northern TrustTRIM-69%$555.0K-$423.0K

Key Facts

  • 15 sellers reduced holdings by $14.7M aggregate; 13 buyers added $1.5M aggregate
  • Fidelity (mega-passive) exited 83.2% of its position, selling $10.0M worth
  • UBS (mega-passive) trimmed 60.4%, selling $2.1M
  • Geode (mega-passive) trimmed 50.7%, selling $1.2M
  • Jane Street Group (active) doubled its position by 3,449%, adding $989K — the largest buyer by dollar amount
  • Goldman Sachs (mega-passive) doubled its stake (+126.4%), adding $162K
  • Marshall Wace (active) doubled (+166.5%), adding $113K
  • RenTech (quant) doubled (+307.7%), adding $67K
  • Net conviction is mixed — passive sellers dominate dollar volume, active/quants are small-scale buyers

Financial Impact

Net institutional selling of $13.2M (buyers $1.5M vs sellers $14.7M) — a 7.7x sell-to-buy ratio by dollar value

institutional ownershipfloatliquidity

Risk Factors

  • Passive fund selling may continue if ATYR is being removed from indices or faces liquidity issues
  • Active buyer conviction is low — Jane Street's large percentage increase is from a tiny base ($38K → $1M)
  • 13F data is 45+ days stale; positions may have already been reversed
  • No insider buying confluence to corroborate the active buyer thesis

Investment Themes

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-ATYR-2026-Q2
13 reports for ATYR
Performance horizon
67% Hit rate @ T+5 2 of 3 directional calls Went positive at some point 3 of 3 best @ T+20▲ +9.09%Aug 7, 2026
Filters
Rows
Reports for ATYR — sortable, filterable
TypeNow
Oct 19, 2026
7d ago
Press Release
NEUTRAL ★ 3/10
$0.1717 $0.1534▼ −10.66%▼ −10.51%—
Oct 7, 2026
19d ago
SC 13G/A
NEUTRAL ★ 3/10
$0.2783 $0.1833▼ −34.14%▼ −33.16%—
Sep 22, 2026
4w ago
Institutional Cluster
BEARISH ★ 4/10
$0.3564 $0.3077▲ +13.66%▲ +12.48%—
Aug 7, 2026
11w ago
8-K
BEARISH ★ 7/10
$0.5289 $0.5189▲ +1.89%▲ +1.84%—
Jun 11, 2026
19w ago
Institutional Cluster
MIXED ★ 4/10
$0.4754 $0.4629▼ −2.63%▼ −3.06%—
Jun 8, 2026
20w ago
8-K
BEARISH ★ 7/10
$0.4556 $0.4433▲ +2.70%▲ +5.11%—
Jun 1, 2026
21w ago
8-K
NEUTRAL ★ 4/10
$0.5200 $0.4560▼ −12.31%▼ −9.34%—
May 15, 2026
23w ago
8-K
BULLISH ★ 5/10
$0.5040 $0.4900▼ −2.78%▼ −3.74%—
May 15, 2026
23w ago
Press Release
NEUTRAL ★ 5/10
$0.5040 $0.4900▼ −2.78%▼ −3.74%—
May 11, 2026
24w ago
8-K
MIXED ★ 6/10
$0.5300 $0.5200▼ −1.89%▼ −1.96%—
Showing 10 of 13

US Market Status

Market Closed — Opens in 3h 56m

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Report published Sep 22, 2026