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ANALYST-UPGRADE ·Filed Aug 13, 2026

ANNX

Annexon, Inc.
BULLISH
Impact 4/10
Processed2mo ago SECanalyst-ANNX-citizens-20260813
Citizens double upgrade: Market Underperform → Market Perform
Actionable Insight ▲ Bullish

The upgrade removes the most bearish Street call and converges with insider buying and positive EPS revisions, but Citizens' poor track record limits conviction. With earnings August 17, this is a timing play — watch for a catalyst-driven move; the elevated short interest adds squeeze potential.

DirectionBullish
Latest settled — T+20d
ANNX ▼ -25.10% at T+20d
LONG call ✗ call lost -25.10% · α vs SPY -23.35% · entry $5.26 → $3.94
Next anchor: T+60d in 10d
Latest observation: T+50 -23.56% FF3 residual α
Entry = T+0 close
Aug 13, 2026
via day close
T+1d
+0.57%
call +0.57% · α +0.77%
$5.29
settled 2mo ago
T+5d
-1.52%
call -1.52% · α +0.44%
$5.18
settled 2mo ago
T+20d
-25.10%
call -25.10% · α -23.35%
$3.94
settled 7w ago
T+60d
Pending
in 10d

Price Chart

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Executive Summary

Citizens double-upgraded Annexon (ANNX) to Market Perform from Market Underperform on August 13, 2026, without setting a price target. The move comes just three weeks after Citizens initiated coverage at Market Underperform with a $3 target, making this a rapid reversal. Consensus remains heavily bullish: 14 of 17 analysts rate the stock Buy or Strong Buy, with a mean target of $13.25 — implying 148% upside from the current $5.34. The upgrade aligns with positive EPS revision momentum (4 upward revisions in the past 7 days) and a notable insider buy of $3.3M by a C-suite executive in late May. However, Citizens has a poor track record — 38% accuracy on 137 calls with a -6.6% average return — which tempers the signal. Short interest is elevated at 55.2% of float, suggesting potential squeeze dynamics. The next earnings report is due August 17, just four days away, adding a timing catalyst. Overall, this is a mildly bullish signal from a low-credibility firm, but the convergence with insider buying and consensus direction gives it modest weight.

Impact Score

Base Score
2/7
LLM Adjustment
+1
Final Score
4/10

Consensus & Targets

Buy / Strong Buy
14 (82%)
Hold
2
Sell / Strong Sell
1
Total Analysts
8
Mean PT
$13.25
Median PT
$11.00
High PT
$27.00
Low PT
$3.00
Current Price
$5.34
Implied Upside
+148.1%

Consensus is heavily bullish: 4 Strong Buy, 10 Buy, 2 Hold, 1 Sell, 0 Strong Sell — 82% Buy/Strong Buy from 17 analysts. The lone Sell is from Citizens' prior rating. Direction is clearly positive, with the upgrade reducing the bearish outlier.

Mean target $13.25, median $11, high $27 (Wells Fargo), low $3 (Citizens' prior). Current price $5.34 implies 148% upside to the mean. Citizens' new rating has no PT, but their prior $3 was the lowest on the Street. The upgrade effectively removes the most bearish outlier, raising the floor.

Recent Analyst Activity

DateFirmActionRatingPrice Target
2026-08-13CitizensupgradeMarket Perform—
2026-07-21CitizensinitiateMarket Underperform$3.00
2026-07-15NeedhammaintainBuy$25.00
2026-05-12Goldman SachsinitiateNeutral$7.00
2026-03-20Chardan CapitalmaintainBuy—
2025-12-23Chardan CapitalinitiateBuy$16.00
2025-12-02Clear StreetinitiateBuy$17.00
2025-11-19Wells FargomaintainOverweight$27.00
2025-08-15HC Wainwright & Co.reiterateBuy$14.00
2025-05-14HC Wainwright & Co.maintainBuy$14.00

30-day analyst activity: 2 upgrades, 0 downgrades. EPS revisions are positive — 4 upward revisions in the past 7 days across all periods, with no downward revisions. Estimates are being revised higher, supporting the bullish consensus.

Firm Track Record — Citizens

Citizens accuracy: 38% on 137 calls | avg return: -6.6%

Industry benchmark: mean 51% ± 11%. Top tier: ≥61% (mean + 1σ). Based on 4 firms with ≥5 scored calls.

FirmAccuracyCallsAvg Returnvs Average
HC Wainwright & Co.50%4/8-7.6%below average
Wells Fargo50%2/4-0.9%below average
Needham38%3/8-3.2%below average
Cantor Fitzgerald20%1/5-14.6%below average

Citizens has a 38% accuracy rate on 137 calls with a -6.6% average return — well below average. Among firms covering ANNX, HC Wainwright (50% on 8 calls) and Wells Fargo (50% on 4 calls) have the best accuracy; Cantor Fitzgerald (20% on 5 calls) is the worst. Citizens' poor track record reduces the credibility of this call.

Earnings Estimates

Next earnings: Aug 17, 2026

PeriodEPS Est.EPS RangeRevenueRevisions (7d)
0q$-0.24$-0.27 — $-0.22$0.00↑4 ↓0
+1q$-0.26$-0.30 — $-0.21$0.00↑4 ↓0
0y$-0.99$-1.14 — $-0.86$0.00↑4 ↓0
+1y$-0.99$-1.28 — $-0.64$40.4M↑3 ↓0

Cross-Platform Signals

Insider Trades (90d)
1 buys / 0 sells
Institutional
Zurcher Kantonalbank (Zurich Cantonalbank) — add (64.3%)
Institutional
Nuveen, LLC — trim (-34.9%)
Institutional
STATE STREET CORP — add (42%)
Short Interest
Short: 503,086 | Exempt: 1 | TRF Vol: 911,729 | Short Ratio: 55.2% | Off-exchange volume (dark pool + OTC)

Insider activity is bullish: a $3.3M buy by C-suite executive Satter Muneer A on May 28, 2026 — a strong signal aligning with the upgrade. Institutional activity is mixed but leans positive: State Street added 42%, Citigroup doubled its position (+665.8%), while Nuveen trimmed 34.9%. Short interest is elevated at 55.2% of float, suggesting potential squeeze risk. No congressional trades reported.

Investment Themes

Documents Analyzed

Report based on filing metadata.

13 reports for ANNX
Performance horizon
57% Hit rate @ T+5 4 of 7 directional calls Went positive at some point 4 of 7 best @ T+20▲ +26.38%Jun 11, 2026
Filters
Rows
Reports for ANNX — sortable, filterable
TypeNow
Aug 13, 2026
10w ago
ANALYST-UPGRADE
BULLISH ★ 4/10
$5.26 $5.18▼ −1.52%▲ +0.44%$3.69 (−29.75%)
Aug 12, 2026
10w ago
8-K
BULLISH ★ 6/10
$5.33 $5.50▲ +3.19%▲ +3.63%$3.69 (−30.68%)
Aug 12, 2026
10w ago
Press Release
BULLISH ★ 6/10
$5.33 $5.50▲ +3.19%▲ +3.63%$3.69 (−30.68%)
Aug 10, 2026
11w ago
8-K
NEUTRAL ★ 4/10
$5.34 $5.28▼ −1.12%▼ −0.72%$3.69 (−30.81%)
Aug 7, 2026
11w ago
Institutional Cluster
MIXED ★ 4/10
$5.41 $5.29▼ −2.22%▼ −2.62%$3.69 (−31.70%)
Aug 6, 2026
11w ago
Press Release
BULLISH ★ 7/10
$5.60 $5.26▼ −6.07%▼ −7.28%$3.69 (−34.02%)
Jul 21, 2026
14w ago
ANALYST-UPGRADE
BULLISH ★ 4/10
$5.39 $5.13▼ −4.82%▼ −3.60%$3.69 (−31.45%)
Jul 14, 2026
15w ago
144
NEUTRAL ★ 2/10
$5.55 $5.57▲ +0.36%▲ +1.66%$3.69 (−33.42%)
Jun 11, 2026
19w ago
Institutional Cluster
BULLISH ★ 5/10
$4.70 $4.94▲ +5.11%▲ +4.67%$3.69 (−21.38%)
May 12, 2026
24w ago
ANALYST-UPGRADE
BEARISH ★ 4/10
$5.44 $4.96▲ +8.82%▲ +8.90%$3.69 (+32.08%)
Showing 10 of 13

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Report published Aug 13, 2026