SecBot SecBot
SC 13G ·Filed Oct 30, 2026

ALNY

ALNYLAM PHARMACEUTICALS, INC.
NEUTRAL
Impact 3/10
Horizonweeks Processed2d 6h ago SEC0002100121-26-001039
Passive investor 5%+ stake
Actionable Insight • Neutral

Vanguard's new 5%+ passive stake signals index-fund-driven accumulation, likely reflecting Alnylam's growing market cap and inclusion weighting. Monitor for further 13G amendments to track position changes, but no activist intent is indicated.

DirectionNeutral
Confidencehigh
Horizonweeks

Price Chart

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Executive Summary

Vanguard Portfolio Management LLC disclosed a 5.03% passive stake in Alnylam Pharmaceuticals as of September 30, 2026, holding 6,732,082 shares. This is a new Schedule 13G filing (not an amendment), indicating Vanguard crossed the 5% threshold for the first time. The filing certifies passive intent with no plans to influence control.

Key Financial Metrics

Stake
5.03%
Investor
Vanguard Portfolio Management LLC
Investor Type
mutual fund

Key Facts

  • Vanguard Portfolio Management LLC filed a new Schedule 13G disclosing 6,732,082 shares of Alnylam common stock
  • Stake represents 5.03% of shares outstanding as of September 30, 2026
  • Filer certifies passive investment intent under Rule 13d-1(b)
  • No prior Vanguard 13G filing for Alnylam found in cross-filing context; this is a new 5%+ disclosure
  • Filing comes one day after Alnylam reported Q3 2026 net product revenues of $1,292M (+52% YoY)

Financial Impact

6,732,082 shares valued at approximately $1.6B based on $31.1B market cap and ~5.03% stake

ownership

Risk Factors

  • Passive 13G filing; no indication of activist intent or plans to influence management
  • Stake just above 5% threshold; Vanguard may adjust position without further disclosure until next threshold crossing

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
76% bullish (38 analysts)

Investment Themes

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
SC 13G Filing (Primary)0002100121-26-001039
Document: 0002100121-26-001039-index.html0002100121-26-001039
Document: 0002100121-26-001039.txt0002100121-26-001039
9 reports for ALNY
Performance horizon
25% Hit rate @ T+5 1 of 4 directional calls Went positive at some point 1 of 5 best @ T+5▲ +26.35%Oct 23, 2026
Filters
Rows
Reports for ALNY, sortable and filterable
TypeNow
Oct 30, 2026
2d ago
SC 13G
NEUTRAL ★ 3/10
$170.53awaiting T+5awaiting T+5$165.00 (−3.24%)
Oct 29, 2026
3d ago
8-K
BULLISH ★ 6/10
$174.00awaiting T+5awaiting T+5$165.00 (−5.17%)
Oct 23, 2026
9d ago
Institutional Cluster
BEARISH ★ 4/10
$224.03 $165.00▲ +26.35%▲ +25.79%$165.00 (+26.35%)
Aug 17, 2026
10w ago
Court Ruling
NEUTRAL ★ 4/10
$228.61 $240.08▲ +5.02%▲ +5.22%$165.00 (−27.82%)
Jul 30, 2026
13w ago
8-K
BEARISH ★ 7/10
$205.48 $216.12▼ −5.18%▼ −1.56%$165.00 (+19.70%)
Jul 28, 2026
13w ago
Institutional Cluster
BULLISH ★ 4/10
$286.62 $228.72▼ −20.20%▼ −25.73%$165.00 (−42.43%)
Mar 3, 2026
34w ago
Insider Cluster
NEUTRAL ★ 3/10
$318.65 $322.38▲ +1.17%▲ +1.65%$165.00 (−48.22%)
Mar 3, 2026
34w ago
Insider Cluster
NEUTRAL ★ 3/10
$318.65 $322.38▲ +1.17%▲ +1.65%$165.00 (−48.22%)
Feb 28, 2026
35w ago
Institutional Cluster
BULLISH ★ 7/10
$325.07 $323.59▼ −0.46%▲ +0.75%$165.00 (−49.24%)
Showing 9 of 9

US Market Status

Market Closed · Opens Mon (< 1m)

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Report published Oct 30, 2026