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S-1 ·Filed Oct 6, 2026

ACTU

ACTUATE THERAPEUTICS, INC.
BEARISH
Impact 7/10
Horizonweeks Processed20d 12h ago SEC0001683168-26-007661
IPO registration
Actionable Insight ▼ Bearish

Monitor the offering's pricing and completion. The company's ability to regain Nasdaq compliance (MVLS >$50M for 10 consecutive days by Jan 11, 2027) is critical — failure could lead to delisting and further liquidity impairment. Watch for clinical data readouts from the oral elraglusib Phase 1/2 study and any partnership/non-dilutive funding for pediatric indications.

DirectionBearish
Confidencehigh
Horizonweeks
Latest settled — T+5d
ACTU ▼ -40.06% at T+5d
SHORT call ✓ call won +40.06% · α vs SPY +39.07% · entry $0.7240 → $0.4340
Next anchor: T+20d in 7d
Latest observation: T+12 +21.49% FF3 residual α
Entry = T+0 close
Oct 6, 2026
via day close
T+1d
-6.22%
call +6.22% · α +5.79%
$0.6790
settled 20d ago
T+5d
-40.06%
call +40.06% · α +39.07%
$0.4340
settled 14d ago
T+20d
Pending
in 7d
T+60d
Pending
in 2mo

Executive Summary

Actuate Therapeutics, a clinical-stage biopharmaceutical company developing elraglusib (a GSK-3 inhibitor for difficult-to-treat cancers), filed an S-1 registration statement for a firm-commitment IPO of 50,000,000 shares of common stock at an assumed price of $0.819 per share (the last reported sale price on October 2, 2026). The company has a going concern qualification, only $4.4M cash as of June 30, 2026, and is not in compliance with Nasdaq's $50M minimum MVLS requirement, making this a dilutive, high-risk capital raise to fund operations and clinical development.

Key Facts

  • Offering 50,000,000 shares (57,500,000 if over-allotment exercised) at $0.819/share, raising ~$38.8M net proceeds.
  • Cash and cash equivalents of $4,425,841 and working capital of $942,745 as of June 30, 2026.
  • Going concern qualification — substantial doubt about ability to continue as a going concern.
  • Not in compliance with Nasdaq Global Market $50M minimum MVLS requirement; received deficiency notice on July 15, 2026.
  • No revenue from product sales; significant operating losses since inception.
  • Underwriter's warrants for 3.5% of shares sold at 125% of IPO price; Bios/Kairos entities receive warrants for 3.7M shares at 150% of IPO price in exchange for 2-year lock-up.
  • Phase 2 mPDAC study met primary endpoint (mOS 10.1 vs 7.2 months, HR=0.62, p=0.02).
  • Post-offering shares outstanding: 74,013,577 (81,513,577 with over-allotment), up from 24,013,577 — massive dilution of ~208%.
  • Net tangible book value per share increases from $0.04 to $0.52, but new investors face $0.30/share immediate dilution.
  • Company has $98.7M remaining capacity under ATM facility and 3,364,407 shares available under Committed Equity Facility.

Financial Impact

Net proceeds of approximately $38.8 million from the offering, providing approximately 8-9 months of runway at current burn rate (based on $4.4M cash and $0.94M working capital as of June 30, 2026).

dilutioncashworking capitalgoing concern

Risk Factors

  • Massive dilution of ~208% from 24M to 74M shares outstanding post-offering.
  • Going concern risk — only $4.4M cash and negative working capital; proceeds may only fund ~8-9 months.
  • Nasdaq delisting risk — not compliant with $50M MVLS requirement; compliance deadline January 11, 2027.
  • Pre-revenue clinical-stage company with no approved products and significant operating losses.
  • Additional overhang from 3.4M shares available under Committed Equity Facility and $98.7M ATM facility.
  • Warrant dilution from underwriter (1.75M shares) and Bios/Kairos (3.7M shares) at exercise prices tied to offering price.

Investment Themes

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
S-1 Filing (Primary)0001683168-26-007661
Document: actuate_s1.htm0001683168-26-007661
Document: actuate_ex0407.htm0001683168-26-007661
10 reports for ACTU
Performance horizon
60% Hit rate @ T+5 3 of 5 directional calls Went positive at some point 3 of 5 best @ T+20▲ +43.03%Apr 14, 2026
Filters
Rows
Reports for ACTU — sortable, filterable
TypeNow
Oct 19, 2026
7d ago
S-1/A
BEARISH ★ 7/10
$0.5990 $0.5279▲ +11.87%▲ +11.72%$0.5280 (+11.85%)
Oct 14, 2026
12d ago
S-1/A
BEARISH ★ 6/10
$0.4342 $0.5622▼ −29.48%▼ −29.03%$0.5280 (−21.60%)
Oct 6, 2026
20d ago
S-1
BEARISH ★ 7/10
$0.7240 $0.4340▲ +40.06%▲ +39.07%$0.5280 (+27.07%)
Aug 12, 2026
10w ago
Institutional Cluster
BEARISH ★ 4/10
$0.9699 $1.06▼ −9.29%▼ −9.73%$0.5280 (+45.56%)
Jun 9, 2026
19w ago
Press Release
BULLISH ★ 7/10
$2.01 $2.05▲ +1.99%▼ −0.42%$0.5280 (−73.73%)
May 11, 2026
24w ago
8-K
MIXED ★ 7/10
$2.89 $2.43▼ −15.92%▼ −15.99%$0.5280 (−81.73%)
May 6, 2026
24w ago
DEFA14A
NEUTRAL ★ 4/10
$2.99 $2.89▼ −3.34%▼ −4.48%$0.5280 (−82.34%)
May 6, 2026
24w ago
8-K
NEUTRAL ★ 4/10
$2.99 $2.89▼ −3.34%▼ −4.48%$0.5280 (−82.34%)
Apr 14, 2026
27w ago
Press Release
BULLISH ★ 8/10
$2.08 $2.27▲ +8.89%▲ +7.50%$0.5280 (−74.62%)
Mar 9, 2026
33w ago
Press Release
NEUTRAL ★ 4/10
$2.95 $2.68▼ −9.00%▼ −7.64%$0.5280 (−82.07%)
Showing 10 of 10

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Report published Oct 6, 2026