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S-1/A ·Filed Oct 19, 2026

ACTU

ACTUATE THERAPEUTICS, INC.
BEARISH
Impact 7/10
Horizonweeks Processed7d 12h ago SEC0001683168-26-007941
IPO registration amendment
Actionable Insight ▼ Bearish

The offering is a distressed capital raise at a deep discount to the stock's already-low price, with proceeds insufficient to fund operations beyond the near term given the company's burn rate and no product revenue. Monitor the Nasdaq compliance deadline (Jan 11, 2027) and the company's ability to secure additional non-dilutive funding or a partnership to extend the cash runway.

DirectionBearish
Confidencehigh
Horizonweeks
Latest settled — T+5d
ACTU ▼ -11.87% at T+5d
SHORT call ✓ call won +11.87% · α vs SPY +11.72% · entry $0.5990 → $0.5279
Next anchor: T+20d in 20d
Entry = T+0 close
Oct 19, 2026
via day close
T+1d
+2.85%
call -2.85% · α -2.52%
$0.6161
settled 7d ago
T+5d
-11.87%
call +11.87% · α +11.72%
$0.5279
settled 13h ago
T+20d
Pending
in 20d
T+60d
Pending
in 3mo

Executive Summary

Actuate Therapeutics filed Pre-Effective Amendment No. 2 to its S-1 registration statement for a public offering of 40,000,000 shares of common stock and 20,000,000 purchase warrants, plus up to 40,000,000 pre-funded warrants, at an assumed combined price of $1.00 per two shares and one warrant. The company is a clinical-stage biopharmaceutical firm developing elraglusib, a GSK-3 inhibitor for difficult-to-treat cancers, and has no product revenue, with cash of $4.4M as of June 30, 2026, and a going concern risk. The offering is highly dilutive (immediate dilution of ~$0.20/share) and the stock trades at $0.50, below the Nasdaq Global Market's $50M MVLS requirement, with a compliance deadline of January 11, 2027.

Key Facts

  • Offering: 40M shares + 20M purchase warrants (5-year term, exercise price TBD) + up to 40M pre-funded warrants ($0.0001 exercise price).
  • Assumed combined offering price: $1.00 per two shares + one warrant; stock closed at $0.50 on Oct 15, 2026.
  • Net proceeds estimated at ~$19.3M (after discounts and expenses), used for working capital and general corporate purposes.
  • Cash and cash equivalents of $4,425,841 as of June 30, 2026; working capital of $942,745.
  • Company has no product revenue and expects to continue incurring significant operating losses.
  • Immediate dilution of ~$0.20 per share for new investors (assumed offering price $0.50 vs. adjusted net tangible book value of $0.30).
  • Nasdaq Global Market non-compliance: MVLS below $50M; must regain compliance by Jan 11, 2027 or face delisting.
  • Top shareholders (Bios and Kairos entities, ~50% combined) agreed to 2-year lock-up; other officers/directors have 120-day lock-up.
  • Underwriter (Newbridge Securities) receives 7% discount, expense reimbursement up to $125K, and warrants for 3.5% of shares sold.
  • Company has a Committed Equity Facility with B. Riley (3.36M shares remaining) and an ATM Facility ($98.7M remaining capacity).

Financial Impact

Net proceeds of ~$19.3M from the offering, with immediate dilution of ~$0.20/share for new investors. Cash position of $4.4M as of June 30, 2026.

dilutioncashworking capital

Risk Factors

  • Nasdaq delisting risk: MVLS below $50M; failure to regain compliance by Jan 11, 2027 could lead to OTC trading and reduced liquidity.
  • Going concern risk: Cash of $4.4M and no product revenue; the offering proceeds (~$19.3M) may not be sufficient to fund operations through key clinical milestones.
  • Extreme dilution: The offering adds 40M shares (166% of current 24M outstanding) plus warrants for another 20M+ shares, severely diluting existing holders.
  • Clinical risk: Elraglusib is still in clinical development; no approved products; Phase 1/2 oral tablet study requires additional funding.
  • Insider selling risk: Despite lock-ups, the large shareholder base (Bios/Kairos at ~50%) could seek liquidity after the 2-year lock-up expires.

Investment Themes

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
S-1/A Filing (Primary)0001683168-26-007941
Document: actuate_s1a.htm0001683168-26-007941
Document: actuate_ex0410.htm0001683168-26-007941
10 reports for ACTU
Performance horizon
60% Hit rate @ T+5 3 of 5 directional calls Went positive at some point 3 of 5 best @ T+20▲ +43.03%Apr 14, 2026
Filters
Rows
Reports for ACTU — sortable, filterable
TypeNow
Oct 19, 2026
7d ago
S-1/A
BEARISH ★ 7/10
$0.5990 $0.5279▲ +11.87%▲ +11.72%$0.4750 (+20.70%)
Oct 14, 2026
12d ago
S-1/A
BEARISH ★ 6/10
$0.4342 $0.5622▼ −29.48%▼ −29.03%$0.4750 (−9.40%)
Oct 6, 2026
20d ago
S-1
BEARISH ★ 7/10
$0.7240 $0.4340▲ +40.06%▲ +39.07%$0.4750 (+34.39%)
Aug 12, 2026
10w ago
Institutional Cluster
BEARISH ★ 4/10
$0.9699 $1.06▼ −9.29%▼ −9.73%$0.4750 (+51.03%)
Jun 9, 2026
19w ago
Press Release
BULLISH ★ 7/10
$2.01 $2.05▲ +1.99%▼ −0.42%$0.4750 (−76.37%)
May 11, 2026
24w ago
8-K
MIXED ★ 7/10
$2.89 $2.43▼ −15.92%▼ −15.99%$0.4750 (−83.56%)
May 6, 2026
24w ago
DEFA14A
NEUTRAL ★ 4/10
$2.99 $2.89▼ −3.34%▼ −4.48%$0.4750 (−84.11%)
May 6, 2026
24w ago
8-K
NEUTRAL ★ 4/10
$2.99 $2.89▼ −3.34%▼ −4.48%$0.4750 (−84.11%)
Apr 14, 2026
27w ago
Press Release
BULLISH ★ 8/10
$2.08 $2.27▲ +8.89%▲ +7.50%$0.4750 (−77.16%)
Mar 9, 2026
33w ago
Press Release
NEUTRAL ★ 4/10
$2.95 $2.68▼ −9.00%▼ −7.64%$0.4750 (−83.87%)
Showing 10 of 10

US Market Status

Market Closed — Opens Wed (12h 38m)

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Report published Oct 19, 2026