| TAK | CLUSTER | neutral | 2/10 | A cluster of 4 Takeda insiders (including C-suite executives) sold shares on August 10, 2026, totaling $1.47M. The broad | Aug 12, 2026 |
| AMGN | CLUSTER | neutral | 2/10 | Two SVPs at Amgen sold a combined $1.63M in open-market sales on August 6, 2026. The total value represents ~0.0007% of | Aug 12, 2026 |
| AMPH | CLUSTER | neutral | 2/10 | Two Amphastar insiders, Director Richard Prins and CFO William Peters, sold a combined $346K in open-market shares over | Aug 12, 2026 |
| REPL | CLUSTER | bullish | 7/10 | A cluster of insider selling by the CMO, CFO, and CAO totaling ~$396K on August 10, 2026, occurred just one day after a | Aug 12, 2026 |
| INSM | CLUSTER | neutral | 4/10 | Insmed's COO and CMO sold a combined $33.1M in stock immediately following a blockbuster Q2 earnings beat (revenue $425. | Aug 12, 2026 |
| BCAX | CLUSTER | neutral | 4/10 | Three top executives at Bicara Therapeutics (CEO, President/COO, CFO) executed same-day option exercises and open-market | Aug 12, 2026 |
| IMNM | CLUSTER | neutral | 4/10 | Two insiders at Immunome sold a total of $2.54M in shares over a week, led by the Chief Business Officer's $2.27M sale. | Aug 12, 2026 |
| ONC | CLUSTER | neutral | 4/10 | CEO John Oyler sold ~$51.8M worth of ONC shares over three days (Aug 10-12), and CFO Aaron Rosenberg sold $362K on Aug 3 | Aug 12, 2026 |
| TWST | CLUSTER | neutral | 4/10 | Twist Bioscience CEO Emily Leproust sold $14.2M in stock on Aug 10, 2026, following the company's strong Q3 earnings bea | Aug 12, 2026 |
| ICLR | CLUSTER | neutral | 2/10 | A cluster of 20 insider sales by 6 directors at ICON PLC over a single day (Aug 11, 2026) totaling ~$1.0M, plus a separa | Aug 12, 2026 |
| PFE | CLUSTER | bullish | 6/10 | Four Pfizer insiders traded within a week of Q2 2026 earnings. Chairman & CEO Albert Bourla and two directors made open- | Aug 12, 2026 |
| LTGO | CLUSTER | bullish | 5/10 | Two 10% owners (Director James Tananbaum and Foresite Capital) each purchased $2.52M of LTGO stock at $18.00/share on Au | Aug 12, 2026 |
| DNTH | CLUSTER | neutral | 3/10 | A cluster of insider selling at Dianthus Therapeutics (DNTH) totaling $2.99M over a 7-day window, led by the CEO ($1.12M | Aug 12, 2026 |
| LLY | CLUSTER | neutral | 3/10 | Two senior Eli Lilly executives (SVP Finance/CAO and EVP GC/Secretary) sold a combined $8.32M in open-market sales over | Aug 12, 2026 |
| TWST | CLUSTER | neutral | 4/10 | A cluster of insider sales at Twist Bioscience totaling $4.39M occurred within 9 days of a strong Q3 2026 earnings beat | Aug 12, 2026 |
| CRL | CLUSTER | neutral | 3/10 | A cluster of insider selling at Charles River Laboratories (CRL) totaling $10.5M in open-market sales occurred within 7 | Aug 12, 2026 |
| UTHR | CLUSTER | neutral | 3/10 | CEO Martine Rothblatt sold ~$5.5M in open-market shares on August 10, 2026, following option exercises, while EVP Paul M | Aug 12, 2026 |
| DNTH | CLUSTER | neutral | 3/10 | Three Dianthus Therapeutics insiders (CEO, General Counsel, and a Director) sold a total of ~$3.2M in open-market shares | Aug 11, 2026 |
| MIRM | CLUSTER | bearish | 5/10 | CEO Christopher Peetz executed a cluster of open-market sales totaling ~$1.98M, including a single-day sale of 11,683 sh | Aug 11, 2026 |
| DNTH | CLUSTER | bearish | 6/10 | CEO Marino Garcia and General Counsel Adam Veness executed a cluster of open-market sales totaling ~$20.0M over two days | Aug 11, 2026 |
| LTGO | CLUSTER | bullish | 6/10 | Two major insiders at Latigo Biotherapeutics (LTGO), a director/10% owner and a 10% owner entity, collectively purchased | Aug 11, 2026 |
| CRL | CLUSTER | neutral | 3/10 | Two senior CRL executives (EVP & Chief People Officer and CEVP, Disc & Safety Assessment) sold a combined ~$2.41M in ope | Aug 11, 2026 |
| UTHR | CLUSTER | neutral | 2/10 | CEO Martine Rothblatt and EVP Paul Mahon sold a combined $989K in open-market shares within two days of United Therapeut | Aug 11, 2026 |
| SYRE | CLUSTER | bearish | 5/10 | Three insiders at Spyre Therapeutics, including the CEO and CFO, sold shares totaling $920K over a one-week window. Dire | Aug 10, 2026 |
| LTGO | CLUSTER | bullish | 6/10 | Two insiders at Latigo Biotherapeutics, a director/10% owner and a 10% owner, purchased a combined 280,000 shares for $5 | Aug 10, 2026 |
| AMGN | CLUSTER | neutral | 2/10 | Two senior Amgen executives (SVP & CCO and SVP, Human Resources) executed open-market sales totaling $1.63M on August 6, | Aug 10, 2026 |
| TRDA | CLUSTER | neutral | 2/10 | Two TRDA insiders, Director Kush Parmar and 10% owner 5AM Ventures, collectively sold ~21K shares for $147K in open-mark | Aug 10, 2026 |
| BLSM | CLUSTER | bullish | 7/10 | Multiple insiders at BlossomHill Therapeutics made significant open-market purchases totaling ~$5.18M, led by director/1 | Aug 10, 2026 |
| IFF | CLUSTER | neutral | 2/10 | Two IFF insiders (CFO and Controller) sold a combined $840K in open-market transactions over two days. The total value r | Aug 10, 2026 |
| CRBP | CLUSTER | neutral | 4/10 | CEO Yuval Cohen and CFO Sean Moran sold a combined $292K in open-market transactions on August 7, 2026, representing ~0. | Aug 10, 2026 |