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Institutional Cluster

ZBIO

Zenas BioPharma, Inc.
BULLISH
Impact 6/10
Horizonweeks Processed8mo ago
Institutional cluster: 3 buyers, 0 sellers (bullish)
Actionable Insight ▲ Bullish

While the buyers are passive managers (suggesting index-driven flows rather than active conviction), the scale of new positions — especially Schwab’s $972K entry and Morgan Stanley’s 6x increase — signals growing institutional footprint. Traders should monitor for follow-through buying and potential float concentration, particularly if active managers begin to participate.

DirectionBullish
Confidencehigh
Horizonweeks
Final — all horizons settled through T+60d
ZBIO ▼ -26.72% at T+60d
LONG call ✗ call lost -26.72% · α vs SPY -36.05% · entry $25.56 → $18.73
Entry = T+0 close
Feb 28, 2026
via day close
T+1d
-1.49%
call -1.49% · α -0.57%
$25.18
settled 8mo ago
T+5d
+2.27%
call +2.27% · α +3.48%
$26.14
settled 8mo ago
T+20d
-28.70%
call -28.70% · α -20.76%
$18.23
settled 7mo ago
T+60d
-26.72%
call -26.72% · α -36.05%
$18.73
settled 5mo ago

Executive Summary

Three major passive institutions — Morgan Stanley, Wells Fargo, and Schwab — significantly increased their positions in Zenas BioPharma during Q4 2024, collectively adding $3.1M in new holdings with no institutional selling observed. This cluster reflects strong institutional accumulation, driven entirely by large passive managers entering or doubling down on positions.

Key Financial Metrics

Direction
accumulating
Buy Value
$3.1M
Net Flow
$3.1M

Institutional Positions

Net institutional flow: $3.1M

▲ Buyers (3)

InstitutionActionChangePosition ValueValue Δ
Morgan StanleyDOUBLED+601.7%$2.9M$2.1M
Wells FargoNEW+0%$65.0K$65.0K
SchwabNEW+0%$972.0K$972.0K

Key Facts

  • Morgan Stanley doubled its position, increasing shares from 51.0K to 358.2K (Δ+307.2K) and value from $864K to $2.9M (Δ+$2.1M)
  • Wells Fargo initiated a new position of 8.0K shares worth $65K
  • Schwab initiated a new position of 118.7K shares worth $972K
  • No institutional sellers were identified in this quarter

Financial Impact

3 institutions accumulated $3.1M in net new positions during Q4 2024 with no offsetting sales

float ownershipinstitutional ownershiptrading volume

Risk Factors

  • All buyers are mega-passive institutions, indicating the move may reflect index inclusion or rebalancing rather than fundamental conviction
  • No active or activist funds are participating, limiting the strength of the signal

Market Snapshot

Exchange
Nasdaq

Investment Themes

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-ZBIO-2024-Q4
18 reports for ZBIO
Performance horizon
100% Hit rate @ T+60 3 of 3 directional calls Went positive at some point 3 of 3 best @ T+60▲ +73.98%May 28, 2026
Filters
Rows
Reports for ZBIO — sortable, filterable
TypeNow
Oct 16, 2026
10d ago
Press Release
NEUTRAL ★ 2/10
$26.71awaiting T+60——
Oct 13, 2026
14d ago
8-K
NEUTRAL ★ 4/10
$25.16awaiting T+60——
Sep 22, 2026
5w ago
Press Release
NEUTRAL ★ 4/10
$33.05awaiting T+60——
Sep 18, 2026
5w ago
Press Release
NEUTRAL ★ 2/10
$32.55awaiting T+60——
Sep 11, 2026
6w ago
S-3ASR
NEUTRAL ★ 5/10
$31.91awaiting T+60——
May 28, 2026
21w ago
Press Release
BULLISH ★ 7/10
$18.56 $32.29▲ +73.98%▲ +72.24%—
May 19, 2026
23w ago
Press Release
BULLISH ★ 7/10
$17.84 $29.20▲ +63.68%▲ +57.39%—
May 13, 2026
23w ago
Press Release
NEUTRAL ★ 4/10
$19.93 $32.43▲ +62.72%▲ +58.28%—
May 13, 2026
23w ago
8-K
NEUTRAL ★ 4/10
$19.93 $32.43▲ +62.72%▲ +58.28%—
May 13, 2026
23w ago
Press Release
NEUTRAL ★ 5/10
$19.93 $32.43▲ +62.72%▲ +58.28%—
Showing 10 of 18

US Market Status

Market Closed — Opens Wed (17h 16m)

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Report published Feb 28, 2026