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SC 13G/A ·Filed Oct 30, 2026

XNCR

Xencor Inc
BEARISH
Impact 4/10
Horizonweeks Processed1d 22h ago SEC0002100119-26-001691
Passive stake amendment
Actionable Insight ▼ Bearish

Vanguard's reduction below 5% removes a large passive holder from reporting obligations, potentially reducing buying support. Monitor for further insider or institutional selling pressure, especially given the clinical-stage nature of Xencor's pipeline and the upcoming End of Phase 1 FDA meeting in 1H2027.

DirectionBearish
Confidencehigh
Horizonweeks

Price Chart

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Executive Summary

Vanguard Capital Management filed an amended Schedule 13G for Xencor Inc, disclosing a reduced passive stake of 3,710,894 shares (4.99%) as of September 30, 2026, down from 10,816,417 shares (14.5%) reported by BlackRock three days earlier. The decrease below the 5% threshold signals a significant reduction in Vanguard's position, though the filing remains a routine passive update by a large asset manager.

Key Financial Metrics

Stake
4.99%
Investor
Vanguard Capital Management LLC
Investor Type
mutual fund

Key Facts

  • Vanguard Capital Management disclosed beneficial ownership of 3,710,894 shares of Xencor common stock as of September 30, 2026.
  • The stake represents 4.99% of outstanding shares, down from a prior level above 5%.
  • The filing is a passive investment disclosure under Rule 13d-1(b); no activist intent is indicated.
  • Vanguard's stake decreased by approximately 65% compared to the 10,816,417 shares (14.5%) reported by BlackRock in a separate 13G/A filed three days earlier.
  • The filing was made by Vanguard Capital Management LLC, including shares held by affiliated entities and Vanguard funds.

Financial Impact

Vanguard reduced its stake by approximately 7.1 million shares, valued at roughly $157 million based on the $2.2B market cap and 4.99% stake. The reduction represents about 9.5% of shares outstanding.

ownership concentrationdilution

Risk Factors

  • Large passive holder reduced stake by ~65%, signaling reduced institutional confidence.
  • Stake now below 5% threshold, eliminating Vanguard's obligation to report future changes.
  • Clinical-stage biotech with no approved products; reliance on regulatory milestones for value inflection.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
85% bullish (20 analysts)

Investment Themes

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
SC 13G/A Filing (Primary)0002100119-26-001691
Document: 0002100119-26-001691-index.html0002100119-26-001691
Document: 0002100119-26-001691.txt0002100119-26-001691
13 reports for XNCR
Performance horizon
50% Hit rate @ T+1 3 of 6 directional calls Went positive at some point 4 of 6 best @ T+60▲ +67.24%May 5, 2026
Filters
Rows
Reports for XNCR, sortable and filterable
TypeNow
Oct 30, 2026
1d ago
SC 13G/A
BEARISH ★ 4/10
$29.09awaiting T+1awaiting T+1$29.82 (−2.51%)
Oct 27, 2026
4d ago
SC 13G/A
NEUTRAL ★ 2/10
$29.99 $29.21▼ −2.60%▼ −2.22%$29.82 (−0.57%)
Oct 26, 2026
6d ago
8-K
BULLISH ★ 6/10
$29.18 $29.99▲ +2.78%▲ +2.22%$29.82 (+2.19%)
Aug 5, 2026
12w ago
8-K
BULLISH ★ 7/10
$20.00 $20.81▲ +4.05%▲ +3.44%$29.82 (+49.10%)
Jun 17, 2026
19w ago
Insider Cluster
NEUTRAL ★ 2/10
$12.64 $14.01▲ +10.84%▲ +11.15%$29.82 (+135.92%)
Jun 15, 2026
19w ago
144
NEUTRAL ★ 2/10
$12.21 $12.20▼ −0.08%▲ +0.51%$29.82 (+144.23%)
Jun 15, 2026
19w ago
144
NEUTRAL ★ 2/10
$12.21 $12.20▼ −0.08%▲ +0.51%$29.82 (+144.23%)
May 6, 2026
25w ago
8-K
BEARISH ★ 7/10
$12.31 $12.31· 0.00%▲ +0.83%$29.82 (−142.24%)
May 5, 2026
25w ago
8-K
BULLISH ★ 7/10
$12.85 $13.01▲ +1.25%▼ −0.14%$29.82 (+132.06%)
Apr 27, 2026
26w ago
8-K
NEUTRAL ★ 3/10
$12.15 $11.64▼ −4.20%▼ −4.19%$29.82 (+145.43%)
Showing 10 of 13

US Market Status

Market Closed · Opens Mon (22h 57m)

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Report published Oct 30, 2026