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424B4 ·Filed Oct 9, 2026

TRXB

TRex Bio, Inc.
NEUTRAL
Impact 5/10
Horizonweeks Processed18d 2h ago SEC0001193125-26-419203
Prospectus supplement
Actionable Insight • Neutral

The IPO provides TRex Bio with approximately 2.5 years of cash runway into H2 2029, funding key catalysts: Phase 1b TRB-061 topline data in mid-2027 and Phase 1 TRB-071 initiation in H1 2027. The bottom-of-range pricing and Lilly's non-binding interest (up to 19.9% post-IPO) suggest measured demand. Monitor the over-allotment exercise and any early lock-up releases for near-term supply dynamics.

DirectionNeutral
Confidencehigh
Horizonweeks
Latest settled — T+5d
TRXB ▲ +5.49% at T+5d
NEUTRAL call +5.49% · α vs SPY +6.98% · entry $14.03 → $14.80
Next anchor: T+20d in 10d
Entry = T+0 close
Oct 9, 2026
via day close
T+1d
-3.06%
call -3.06% · α -3.05%
$13.60
settled 15d ago
T+5d
+5.49%
call +5.49% · α +6.98%
$14.80
settled 11d ago
T+20d
Pending
in 10d
T+60d
Pending
in 2mo

Executive Summary

TRex Bio, Inc. has priced its initial public offering of 8,333,334 shares of common stock at $14.00 per share, raising approximately $108.5 million in gross proceeds before underwriting discounts and commissions. The offering was upsized from the preliminary range of $14.00-$16.00 per share and closed at the bottom of that range. Net proceeds of approximately $103.5 million will fund Phase 2 trials for TRB-061 in atopic dermatitis and alopecia areata, a Phase 1 trial for TRB-071, and working capital. The IPO converts all outstanding redeemable convertible preferred stock into common stock and establishes a public market for the company's shares on Nasdaq under the ticker TRXB.

Key Financial Metrics

Offering Size
$116.7M
Underwriters
J.P. Morgan, Evercore ISI +3

Key Facts

  • IPO priced at $14.00 per share, the bottom of the $14.00-$16.00 preliminary range
  • 8,333,334 shares sold by the company; total gross proceeds of $116,666,676
  • Net proceeds to the company estimated at $103.5 million (or $119.8 million if underwriters exercise the 1,250,000-share over-allotment option)
  • Underwriters include J.P. Morgan, Evercore ISI, Cantor, Stifel, and Wedbush PacGrow
  • Shares to be listed on Nasdaq under ticker TRXB; delivery expected October 13, 2026
  • Proceeds allocated: ~$90M for TRB-061 Phase 2 trials (AD and AA), ~$10M for TRB-071 Phase 1, remainder for working capital
  • Eli Lilly has indicated non-binding interest to purchase shares up to 19.9% of post-IPO outstanding shares
  • Post-IPO shares outstanding: 27,445,682 (or 28,695,682 if over-allotment exercised)
  • Company had $90.9M in cash, cash equivalents, and marketable securities as of June 30, 2026
  • Net loss of $29.3M for the six months ended June 30, 2026; accumulated deficit of $123.6M

Financial Impact

IPO raises $116.7M gross ($108.5M net before expenses); net proceeds of ~$103.5M extend cash runway into H2 2029. Immediate dilution of $7.04 per share for new investors (50.3% dilution from IPO price of $14.00 to pro forma as adjusted net tangible book value of $6.96).

dilutioncash runwayshares outstanding

Risk Factors

  • Clinical-stage biotech with no approved products; TRB-061 and TRB-071 are early-stage and may fail in trials
  • Material weakness in internal controls over financial reporting identified and not yet remediated
  • Preclinical safety findings for TRB-061 (monkey deaths in toxicology studies) could lead to clinical holds or exposure caps
  • Substantial additional capital needed beyond IPO proceeds to complete development; future dilution likely
  • Lilly's non-binding interest is not a firm commitment; actual purchases may be less or none

Documents Analyzed

This report is based on 4 SEC documents filed with EDGAR.

DocumentAccession Number
424B4 Filing (Primary)0001193125-26-419203
Document: 0001193125-26-419203-index-headers.html0001193125-26-419203
Document: 0001193125-26-419203-index.html0001193125-26-419203
Document: 0001193125-26-419203.txt0001193125-26-419203
22 reports for TRXB
Performance horizon
100% Hit rate @ T+1 3 of 3 directional calls Went positive at some point 3 of 3 best @ T+1▲ +5.64%Oct 15, 2026
Filters
Rows
Reports for TRXB — sortable, filterable
TypeNow
Oct 16, 2026
11d ago
SC 13G
NEUTRAL ★ 3/10
$14.80 $14.44▼ −2.43%▼ −2.77%$13.79 (−6.82%)
Oct 16, 2026
11d ago
SC 13D
NEUTRAL ★ 5/10
$14.80 $14.44▼ −2.43%▼ −2.77%$13.79 (−6.82%)
Oct 16, 2026
11d ago
SC 13D
NEUTRAL ★ 5/10
$14.01 $14.80▲ +5.64%▲ +5.22%$13.79 (−1.57%)
Oct 15, 2026
12d ago
Insider Cluster
BULLISH ★ 5/10
$14.01 $14.80▲ +5.64%▲ +5.22%$13.79 (−1.57%)
Oct 15, 2026
12d ago
SC 13G
NEUTRAL ★ 3/10
$14.16 $14.01▼ −1.06%▲ +0.05%$13.79 (−2.61%)
Oct 13, 2026
14d ago
Press Release
NEUTRAL ★ 5/10
$13.50 $14.16▲ +4.89%▲ +4.60%$13.79 (+2.15%)
Oct 9, 2026
18d ago
424B4
NEUTRAL ★ 5/10
$14.03 $13.60▼ −3.06%▼ −3.05%$13.79 (−1.71%)
Oct 9, 2026
18d ago
EFFECT
BULLISH ★ 7/10
$14.00 $14.03▲ +0.21%▲ +0.27%$13.79 (−1.50%)
Oct 8, 2026
18d ago
3
NEUTRAL ★ 3/10
$14.00 $14.03▲ +0.21%▲ +0.27%$13.79 (−1.50%)
Oct 8, 2026
18d ago
3
NEUTRAL ★ 2/10
$14.00 $14.03▲ +0.21%▲ +0.27%$13.79 (−1.50%)
Showing 10 of 22

US Market Status

Market Closed — Opens Wed (< 1m)

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Report published Oct 9, 2026