The divergence between aggressive hedge fund selling and asset manager accumulation creates uncertainty. Traders should watch for a potential catalyst (e.g., pipeline data, earnings) that could resolve this tension. The 45-day 13F lag means these positions may have already changed — monitor for additional filings (e.g., SC 13D/G or subsequent 13F) to confirm the trend.
Executive Summary
In Q3 2024, institutional activity in TGTX reveals a sharp split: 16 buyers added $41.8M in positions, led by asset managers (Ameriprise, Prudential) and quant (D.E. Shaw), while 14 sellers reduced holdings by $67.5M, including full exits by Point72 and Balyasny and a near-exit by Citadel. The net institutional flow is negative by ~$25.7M, with aggressive hedge fund selling contrasting with longer-term accumulation, creating an ambiguous signal.
Key Financial Metrics
Institutional Positions
Net institutional flow: -$25.7M
▲ Buyers (16)
| Institution | Action | Change | Position Value | Value Δ |
|---|---|---|---|---|
| Invesco | ADD | +95.3% | $21.5M | $13.1M |
| Ameriprise Financial | DOUBLED | +247.1% | $10.7M | $8.4M |
| Prudential Financial | DOUBLED | +256.7% | $7.1M | $5.6M |
| D.E. Shaw | ADD | +64.5% | $9.2M | $5.0M |
| Rhumbline Advisers | ADD | +77.9% | $8.9M | $5.1M |
▼ Sellers (14)
| Institution | Action | Change | Prev Value | Value Δ |
|---|---|---|---|---|
| Citadel | NEAR_EXIT | -93.3% | $33.1M | -$30.2M |
| Balyasny Asset Management | EXIT | -100% | $14.3M | -$14.3M |
| Point72 | EXIT | -100% | $10.4M | -$10.4M |
| Assenagon Asset Management | TRIM | -65.2% | $8.7M | -$4.7M |
| Capital Fund Management | TRIM | -66.1% | $6.9M | -$3.8M |
Key Facts
- 16 buyers added a net $41.8M; sellers reduced by $67.5M (net -$25.7M)
- Invesco (passive) added +95% shares, worth $13.1M increase
- D.E. Shaw (quant) added +65%, worth $5.0M increase
- Ameriprise doubled its position, adding $8.4M
- Prudential doubled, adding $5.6M
- Point72 exited entirely (-$10.4M), Balyasny exited entirely (-$14.3M), Citadel nearly exited (-$30.2M)
- Sellers include three multi-manager/quant hedge funds (Point72, Citadel, Balyasny) with high conviction exits
Financial Impact
Net institutional selling of approximately $25.7M, with $67.5M in seller reductions only partially offset by $41.8M in buyer additions. Hedge fund exits (Point72, Balyasny, Citadel) total ~$54.9M in reduced holdings.
Risk Factors
- Hedge fund exits may reflect informed negative expectations not yet public
- 13F reporting lag means positions could be stale
- Mixed institutional signals complicate near-term direction
Market Snapshot
Investment Themes
Documents Analyzed
This report is based on 1 institutional 13F filing from SEC EDGAR.
| Document | Accession Number |
|---|---|
| INST-CLUSTER Data (Synthetic) | inst-cluster-TGTX-2024-Q3 |
Filters
| Type | Now | ||||
|---|---|---|---|---|---|
Aug 3, 2026 12w ago | 8-K | $46.17 | awaiting T+60 | — | — |
Jun 11, 2026 19w ago | Institutional Cluster | $49.52 $55.74 | ▲ +12.56% | ▲ +9.30% | — |
Jun 3, 2026 20w ago | 8-K | $40.11 $55.72 | ▲ +38.92% | ▲ +36.42% | — |
Jun 3, 2026 20w ago | Press Release | $40.11 $55.72 | ▲ +38.92% | ▲ +36.42% | — |
Jun 1, 2026 21w ago | Press Release | $37.41 $55.42 | ▲ +48.14% | ▲ +46.91% | — |
May 27, 2026 21w ago | 8-K | $38.82 $54.27 | ▲ +39.80% | ▲ +38.06% | — |
May 6, 2026 24w ago | 8-K | $41.97 $52.03 | ▲ +23.97% | ▲ +21.91% | — |
Apr 30, 2026 25w ago | Press Release | $33.78 $55.75 | ▲ +65.04% | ▲ +61.93% | — |
Apr 22, 2026 26w ago | Press Release | $38.31 $54.87 | ▲ +43.23% | ▲ +38.45% | — |
Apr 15, 2026 27w ago | Press Release | $34.60 $57.12 | ▲ +65.09% | ▲ +56.95% | — |
US Market Status
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