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8-K ·Filed May 7, 2026

SLNCF

Silence Therapeutics plc
NEUTRAL
Impact 4/10
Horizonmonths Processed5mo ago SEC0001193125-26-210428
8-K Item 2.02: Earnings release
Actionable Insight • Neutral

The stock will trade on SANRECO Phase 2 readout in August 2026, not Q1 financials. Monitor abstract presentations at EHA (June) and EAS (May) for additional pipeline signals.

DirectionNeutral
Confidencehigh
Horizonmonths
Final — all horizons settled through T+60d
SLNCF ▼ -42.97% at T+60d
NEUTRAL call -42.97% · α vs SPY -46.80% · entry $2.63 → $1.50
Entry = T+0 close
May 7, 2026
via day close
T+1d
0.00%
call 0.00% · α -0.83%
$2.63
settled 6mo ago
T+5d
-44.77%
call -44.77% · α -46.28%
$1.45
settled 6mo ago
T+20d
-59.70%
call -59.70% · α -62.83%
$1.06
settled 5mo ago
T+60d
-42.97%
call -42.97% · α -46.80%
$1.50
settled 3mo ago

Price Chart

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Executive Summary

Silence Therapeutics reported Q1 2026 revenue of $0.4M vs consensus $1.5M, a significant miss reflecting early-stage biotech volatility. Net loss narrowed to $15.0M ($0.11 per share) from $28.5M YoY, driven by lower R&D spend. The key catalyst remains Phase 2 SANRECO topline in August 2026.

Key Financial Metrics

EPS
−$0.11
Revenue
$422.0K
est $1.5M · -71.9% · +197.2% YoY
Rating
miss

Key Facts

  • Q1 2026 revenue $0.4M; consensus was $1.5M (miss)
  • Net loss $15.0M vs $28.5M YoY, improvement due to lower R&D expenses
  • Cash & investments $70.1M as of March 31, 2026
  • Phase 2 SANRECO trial (divesiran) on track for topline results in August 2026
  • SLN312 Phase 1 abstract accepted for late-breaking oral at EAS Congress

Financial Impact

Revenue miss of $1.1M (73% below consensus) but pre-revenue biotech; cash burn manageable

revenuenet losscash position

Risk Factors

  • Phase 2 SANRECO trial failure or delay
  • Cash runway only ~12 quarters at current burn rate without additional partnering or financing

Market Snapshot

Exchange
OTC
Sector
Pharmaceutical Preparations

Investment Themes

Documents Analyzed

This report is based on 6 SEC documents filed with EDGAR.

DocumentAccession Number
8-K Filing (Primary)0001193125-26-210428
Document: sln-20260507.htm0001193125-26-210428
Document: 0001193125-26-210428-index-headers.html0001193125-26-210428
Document: 0001193125-26-210428-index.html0001193125-26-210428
Document: 0001193125-26-210428.txt0001193125-26-210428
8-K Data (Synthetic)0001193125-26-210428
4 reports for SLNCF
Performance horizon
33% Hit rate @ T+5 1 of 3 directional calls Went positive at some point 1 of 3 best @ T+1▲ +27.02%May 18, 2026
Filters
Rows
Reports for SLNCF — sortable, filterable
TypeNow
May 28, 2026
21w ago
EFFECT
BEARISH ★ 5/10
$1.06 $1.06· 0.00%▲ +0.33%$6.37 (−500.94%)
May 27, 2026
21w ago
424B5
BEARISH ★ 6/10
$1.06 $1.06· 0.00%▲ +0.33%$6.37 (−500.94%)
May 18, 2026
23w ago
S-3
BEARISH ★ 6/10
$1.45 $1.06▲ +27.02%▲ +29.32%$6.37 (−338.55%)
May 7, 2026
24w ago
8-K
NEUTRAL ★ 4/10
$2.63 $1.45▼ −44.77%▼ −46.28%$6.37 (+142.21%)
Showing 4 of 4

US Market Status

Market Open — Closes in 50m

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Report published May 7, 2026