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SC 13G/A ·Filed Oct 13, 2026

SLN

Silence Therapeutics plc
NEUTRAL
Impact 3/10
Horizonweeks Processed13d 4h ago SEC0000919574-26-006906
Passive stake amendment
Actionable Insight • Neutral

Tetragon's passive stake at 5.3% is unchanged — no new buying or selling signal. Monitor for any future conversion to a 13D filing, which would indicate activist intent. The call option component (500,000 ADSs) adds modest upside exposure but does not change the passive characterization.

DirectionNeutral
Confidencehigh
Horizonweeks
Latest settled — T+5d ⚠ clustered
SLN ▲ +119.04% at T+5d
NEUTRAL call +119.04% · α vs SPY +118.59% · entry $8.98 → $19.67
Next anchor: T+20d in 14d
Latest observation: T+7 +130.70% FF3 residual α
Entry = T+0 close
Oct 13, 2026
via day close
T+1d
+4.12%
call +4.12% · α +3.84%
$9.35
settled 13d ago
T+5d
+119.04%
call +119.04% · α +118.59%
$19.67
settled 7d ago
T+20d
Pending
in 14d
T+60d
Pending
in 2mo

Price Chart

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Executive Summary

Tetragon Financial Management LP and related entities filed an amended Schedule 13G disclosing a 5.3% passive stake in Silence Therapeutics plc, representing 9,878,565 ordinary shares (held as ADSs and call options). The filing confirms a passive position with no activist intent, and the stake is unchanged from the initial filing on the same date.

Key Financial Metrics

Stake
5.3%
Investor
Tetragon Financial Management LP
Investor Type
hedge fund

Key Facts

  • Tetragon Financial Group Limited and related entities hold 9,878,565 ordinary shares (5.3% of outstanding) in Silence Therapeutics plc.
  • The stake is represented by 3,292,855 ADSs (each ADS = 3 ordinary shares), including 1,500,000 shares underlying call options.
  • The filing is an amendment to the initial Schedule 13G filed on October 13, 2026, and restates the same position.
  • The percentage is based on 186,461,401 shares outstanding as reported in the company's August 2026 prospectus and press release.
  • The filers certify passive intent under Rule 13d-1(c), disclaiming any control purpose.

Financial Impact

No financial impact — the stake is unchanged from the initial filing.

Risk Factors

  • Tetragon could convert to an activist 13D filer, though the current filing explicitly disclaims control intent.
  • The stake is below the 5% threshold for most passive filings, but the filers have disclosed it voluntarily.

Investment Themes

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
SC 13G/A Filing (Primary)0000919574-26-006906
Document: 0000919574-26-006906-index.html0000919574-26-006906
Document: 0000919574-26-006906.txt0000919574-26-006906
10 reports for SLN
Performance horizon
80% Hit rate @ T+1 4 of 5 directional calls Went positive at some point 4 of 5 best @ T+20▲ +7.95%Aug 10, 2026
Filters
Rows
Reports for SLN — sortable, filterable
TypeNow
Oct 19, 2026
7d ago
DEFA14A
BULLISH ★ 7/10
$19.61 $19.67▲ +0.31%▼ −0.22%$19.78 (+0.87%)
Oct 19, 2026
7d ago
DEFA14A
BULLISH ★ 8/10
$19.58 $19.61▲ +0.15%▼ −0.18%$19.78 (+1.02%)
Oct 19, 2026
7d ago
8-K
BULLISH ★ 9/10
$19.58 $19.61▲ +0.15%▼ −0.18%$19.78 (+1.02%)
Oct 13, 2026
13d ago
SC 13G/A
NEUTRAL ★ 3/10
$8.98 $9.35▲ +4.12%▲ +3.84%$19.78 (+120.27%)
Oct 13, 2026
13d ago
SC 13G
NEUTRAL ★ 3/10
$8.98 $9.35▲ +4.12%▲ +3.84%$19.78 (+120.27%)
Aug 10, 2026
11w ago
424B5
BEARISH ★ 7/10
$14.72 $13.58▲ +7.74%▲ +8.00%$19.78 (−34.38%)
Aug 10, 2026
11w ago
8-K
BULLISH ★ 7/10
$15.43 $14.72▼ −4.60%▼ −4.28%$19.78 (+28.19%)
Aug 10, 2026
11w ago
8-K
NEUTRAL ★ 5/10
$15.43 $14.72▼ −4.60%▼ −4.28%$19.78 (+28.19%)
Jun 23, 2026
17w ago
8-K
NEUTRAL ★ 3/10
$9.16 $10.00▲ +9.17%▲ +9.03%$19.78 (+115.94%)
Mar 5, 2026
33w ago
8-K
MIXED ★ 6/10
$5.50 $6.23▲ +13.27%▲ +14.59%$19.78 (+259.64%)
Showing 10 of 10

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Report published Oct 13, 2026