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Insider Cluster (2 insiders) ·Filed Sep 18, 2026

PVLA

PALVELLA THERAPEUTICS, INC.
BEARISH
Impact 6/10
Horizondays Processed1mo ago
Insider cluster: 2 insiders, $336K total
Actionable Insight ▼ Bearish

The director's concentrated open-market selling without a 10b5-1 plan is a material bearish signal for a clinical-stage biotech. Monitor for any upcoming corporate events (data readouts, financing, or partnership news) that may have prompted the selling. The next 8-K or press release should be scrutinized for negative developments.

DirectionBearish
Confidencemedium
Horizondays
Latest settled — T+20d
PVLA ▼ -19.85% at T+20d
SHORT call ✓ call won +19.85% · α vs SPY +18.94% · entry $153.41 → $122.96
Next anchor: T+60d in 7w
Latest observation: T+24 +22.15% FF3 residual α
Entry = T+0 close
Sep 21, 2026
via day close
T+1d
+3.08%
call -3.08% · α -3.09%
$158.13
settled 5w ago
T+5d
-8.85%
call +8.85% · α +7.83%
$139.83
settled 29d ago
T+20d
-19.85%
call +19.85% · α +18.94%
$122.96
settled 8d ago
T+60d
Pending
in 7w

Price Chart

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Executive Summary

Director George M. Jenkins sold a total of ~27,500 shares worth ~$4.17M in open-market sales over three trading days (Sep 11-15), while COO Kathleen Goin sold ~1,700 shares worth ~$251K on Sep 16. The combined insider selling of ~$4.4M represents roughly 1.3% of PVLA's ~$326M market cap, a significant cluster of open-market sales by a director with no indicated 10b5-1 plan. This is a bearish signal for a clinical-stage biotech, as the director's concentrated selling is not liquidity-driven (no plan, no tax withholding).

Key Financial Metrics

Direction
selling
Total Value
$4.4M
Insiders
2

Key Facts

  • Director George M. Jenkins sold ~27,500 shares in open-market sales totaling ~$4.17M over Sep 11-15.
  • COO Kathleen Goin sold ~1,700 shares in open-market sale totaling ~$251K on Sep 16.
  • Total insider selling of ~$4.4M represents ~1.3% of PVLA's market cap (~$326M).
  • No 10b5-1 plan indicated for any of the sales.
  • Jenkins' sales were concentrated across three days with no regular pattern suggesting a pre-arranged plan.

Financial Impact

Director sold ~$4.17M in open-market shares (1.3% of market cap); COO sold ~$251K.

insider ownershipmarket sentiment

Risk Factors

  • Director selling may signal adverse clinical data or financing concerns.
  • COO selling adds to the bearish signal, though smaller in magnitude.
  • Clinical-stage biotechs are highly sensitive to insider selling patterns.

Investment Themes

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-PVLA-1789797884841
28 reports for PVLA
Performance horizon
60% Hit rate @ T+60 3 of 5 directional calls Went positive at some point 4 of 6 best @ T+60▲ +35.07%May 15, 2026
Filters
Rows
Reports for PVLA — sortable, filterable
TypeNow
Oct 23, 2026
3d ago
Insider Cluster
NEUTRAL ★ 2/10
$125.10awaiting T+60—$131.07 (+4.77%)
Oct 15, 2026
12d ago
Press Release
NEUTRAL ★ 4/10
$127.34awaiting T+60—$131.07 (+2.93%)
Oct 13, 2026
13d ago
144
NEUTRAL ★ 4/10
$122.58awaiting T+60—$131.07 (+6.93%)
Sep 18, 2026
5w ago
Insider Cluster
BEARISH ★ 6/10
$153.41awaiting T+60—$131.07 (+14.56%)
Sep 2, 2026
7w ago
144
NEUTRAL ★ 2/10
$155.47awaiting T+60—$131.07 (−15.69%)
Aug 9, 2026
11w ago
Institutional Cluster
BULLISH ★ 6/10
$152.22awaiting T+60—$131.07 (−13.89%)
Aug 4, 2026
12w ago
8-K
NEUTRAL ★ 5/10
$151.99awaiting T+60—$131.07 (−13.76%)
Jul 30, 2026
12w ago
Press Release
NEUTRAL ★ 2/10
$150.19 $125.10▼ −16.71%▼ −19.17%$131.07 (−12.73%)
Jul 28, 2026
13w ago
Press Release
NEUTRAL ★ 1/10
$142.84 $126.58▼ −11.38%▼ −15.73%$131.07 (−8.24%)
Jun 30, 2026
17w ago
8-K
NEUTRAL ★ 2/10
$152.82 $149.56▼ −2.13%▼ −5.70%$131.07 (−14.23%)
Showing 10 of 28

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Report published Sep 18, 2026