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8-K ·Filed Apr 16, 2026

PRME

Prime Medicine, Inc.
NEUTRAL
Impact 3/10
Horizonweeks Processed6mo ago SEC0001628280-26-025372
8-K context-dependent: Items 5.02
Actionable Insight • Neutral

Monitor CFO integration and upcoming financial guidance for signs of strategic direction changes. The equity grants represent potential dilution of approximately 1.3% of current market cap.

DirectionNeutral
Confidencehigh
Horizonweeks
Final — all horizons settled through T+60d
PRME ▼ -4.22% at T+60d
NEUTRAL call -4.22% · α vs SPY -11.27% · entry $3.67 → $3.52
Entry = T+0 close
Apr 16, 2026
via day close
T+1d
+3.81%
call +3.81% · α +2.60%
$3.81
settled 6mo ago
T+5d
+4.63%
call +4.63% · α +3.65%
$3.84
settled 6mo ago
T+20d
-10.90%
call -10.90% · α -16.71%
$3.27
settled 6mo ago
T+60d
-4.22%
call -4.22% · α -11.27%
$3.52
settled 4mo ago

Price Chart

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Executive Summary

Prime Medicine appointed Svetlana Makhni as CFO effective April 16, 2026, with a $495,000 base salary, 40% bonus target, $40,000 sign-on bonus, and options to purchase 900,000 shares. CEO Allan Reine stepped down from the principal financial officer role.

Key Facts

  • Svetlana Makhni appointed CFO effective April 16, 2026
  • Annual base salary of $495,000 with 40% target bonus
  • Sign-on bonus of $40,000
  • Time-based option grant for 800,000 shares vesting over 4 years
  • Milestone-based option grant for 100,000 shares
  • Allan Reine stepped down as principal financial officer
  • Employment agreement includes severance of 9 months base salary plus 75% of target bonus if terminated without cause

Financial Impact

Approximately $3.96 million in potential compensation over 4 years including salary, target bonus, sign-on bonus, and equity grants based on current market value

compensationdilutionoperating expenses

Risk Factors

  • Integration risk with new CFO
  • Potential dilution from equity grants
  • Leadership transition in key financial role

Market Snapshot

Exchange
Nasdaq
Sector
Biological Products, (No Diagnostic Substances)

Investment Themes

Documents Analyzed

This report is based on 5 SEC documents filed with EDGAR.

DocumentAccession Number
8-K Filing (Primary)0001628280-26-025372
Document: prme-20260407.htm0001628280-26-025372
Document: 0001628280-26-025372-index-headers.html0001628280-26-025372
Document: 0001628280-26-025372-index.html0001628280-26-025372
Document: 0001628280-26-025372.txt0001628280-26-025372
8 reports for PRME
Performance horizon
50% Hit rate @ T+60 2 of 4 directional calls Went positive at some point 5 of 6 best @ T+20▲ +26.55%Sep 24, 2026
Filters
Rows
Reports for PRME — sortable, filterable
TypeNow
Sep 24, 2026
4w ago
Press Release
BULLISH ★ 7/10
$2.90awaiting T+60—$4.35 (+50.00%)
Aug 6, 2026
11w ago
8-K
BULLISH ★ 6/10
$2.95awaiting T+60—$4.35 (+47.46%)
Jul 8, 2026
15w ago
8-K
BULLISH ★ 6/10
$4.62 $3.06▼ −33.87%▼ −36.19%$4.35 (−5.84%)
Jun 18, 2026
18w ago
Press Release
BULLISH ★ 6/10
$3.23 $3.18▼ −1.55%▼ −3.44%$4.35 (+34.67%)
May 7, 2026
24w ago
8-K
BEARISH ★ 6/10
$3.12 $2.81▲ +9.79%▲ +13.62%$4.35 (−39.65%)
May 7, 2026
24w ago
Press Release
BEARISH ★ 5/10
$3.12 $2.81▲ +9.79%▲ +13.62%$4.35 (−39.65%)
Apr 16, 2026
27w ago
8-K
NEUTRAL ★ 3/10
$3.67 $3.52▼ −4.22%▼ −11.27%$4.35 (+18.53%)
Mar 3, 2026
34w ago
Press Release
MIXED ★ 6/10
$4.23 $3.30▼ −21.99%▼ −32.30%$4.35 (+2.84%)
Showing 8 of 8

US Market Status

Market Closed — Opens Wed (16h 25m)

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Report published Apr 16, 2026