SecBot SecBot
424B4 ·Filed Jun 10, 2026

PBLS

Parabilis Medicines, Inc.
BULLISH
Impact 7/10
Horizonmonths Processed4mo ago SEC0001193125-26-265983
Prospectus supplement
Actionable Insight ▲ Bullish

The IPO prices a pre-revenue biotech at a ~$2.3B market cap (based on 116.6M shares post-offering at $20). Key catalysts to watch: initiation of Phase 3 registrational trial for zolucatetide in desmoid tumors (expected H1 2027), data from ongoing Phase 1/2 trials across multiple indications, and progress of ERG/ARON degrader preclinical programs. The ~$1.0B cash runway into H2 2029 reduces near-term dilution risk but shifts focus to clinical execution.

DirectionBullish
Confidencehigh
Horizonmonths
Final — all horizons settled through T+60d ⚠ clustered
PBLS ▲ +33.36% at T+60d
LONG call ✓ call won +33.36% · α vs SPY +28.96% · entry $30.31 → $40.42
Entry = T+0 close
Jun 10, 2026
via day close
T+1d
-10.06%
call -10.06% · α -10.60%
$27.26
settled 5mo ago
T+5d
-14.12%
call -14.12% · α -14.55%
$26.03
settled 4mo ago
T+20d
+0.17%
call +0.17% · α -1.73%
$30.36
settled 4mo ago
T+60d
+33.36%
call +33.36% · α +28.96%
$40.42
settled 7w ago

Executive Summary

Parabilis Medicines priced its IPO of 33,500,000 shares at $20.00/share, raising approximately $623.1 million in gross proceeds (before underwriting discounts and expenses). Additionally, Regeneron is investing $75.0 million in a concurrent private placement at $18.00/share (90% of the IPO price). Combined with a $50.0 million upfront from Regeneron under a May 2026 collaboration, the company expects total pro forma as-adjusted cash of ~$1.02 billion, sufficient to fund operations into H2 2029.

Key Financial Metrics

Offering Size
$670.0M
Dilution
28.4%
Underwriters
Leerink Partners, BofA Securities +3

Key Facts

  • 33,500,000 shares offered at $20.00/share, total gross proceeds $670,000,000
  • Underwriters' overallotment option of 5,025,000 additional shares
  • Regeneron concurrent private placement: 4,166,666 shares at $18.00/share ($75.0M total)
  • Net proceeds to company: ~$618.2M from IPO, plus ~$75.0M from private placement
  • Pro forma as-adjusted cash position: $1,022,239,000 as of March 31, 2026
  • Cash runway extended into H2 2029; funds Phase 3 desmoid tumor trial, pipeline expansion

Financial Impact

$670M gross IPO proceeds + $75M Regeneron PIPE = $745M total gross proceeds; net proceeds ~$693.2M after underwriting and expenses

cashPositionshareCountvaluation

Risk Factors

  • Pre-revenue clinical-stage biotech with no approved products; high risk of trial failure
  • Novel modality (Helicons) with unproven regulatory path
  • Dilution from 33.5M new shares (28.4% of post-IPO float) and option overhang
  • Substantial additional capital likely needed before reaching profitability

Documents Analyzed

This report is based on 4 SEC documents filed with EDGAR.

DocumentAccession Number
424B4 Filing (Primary)0001193125-26-265983
Document: 0001193125-26-265983-index-headers.html0001193125-26-265983
Document: 0001193125-26-265983-index.html0001193125-26-265983
Document: 0001193125-26-265983.txt0001193125-26-265983
23 reports for PBLS
Performance horizon
83% Hit rate @ T+60 5 of 6 directional calls Went positive at some point 8 of 8 best @ T+60▲ +38.92%Jun 16, 2026
Filters
Rows
Reports for PBLS — sortable, filterable
TypeNow
Oct 24, 2026
2d ago
Press Release
BULLISH ★ 7/10
$24.79awaiting T+60—$25.03 (+0.97%)
Oct 19, 2026
7d ago
Press Release
NEUTRAL ★ 4/10
$25.35awaiting T+60—$25.03 (−1.26%)
Sep 15, 2026
5w ago
8-K
NEUTRAL ★ 2/10
$36.88awaiting T+60—$25.03 (−32.13%)
Sep 2, 2026
7w ago
8-K
NEUTRAL ★ 3/10
$40.75awaiting T+60—$25.03 (−38.58%)
Aug 13, 2026
10w ago
8-K
BULLISH ★ 7/10
$35.67awaiting T+60—$25.03 (−29.83%)
Aug 13, 2026
10w ago
Press Release
BULLISH ★ 7/10
$35.67awaiting T+60—$25.03 (−29.83%)
Jul 22, 2026
13w ago
Insider Buy
BULLISH ★ 6/10
$32.81 $22.75▼ −30.66%▼ −34.31%$25.03 (−23.71%)
Jun 29, 2026
17w ago
Insider Cluster
BULLISH ★ 9/10
$29.19 $33.31▲ +14.11%▲ +10.50%$25.03 (−14.25%)
Jun 16, 2026
18w ago
Insider Cluster
BULLISH ★ 8/10
$26.03 $36.16▲ +38.92%▲ +36.23%$25.03 (−3.84%)
Jun 15, 2026
18w ago
Insider Cluster
BULLISH ★ 9/10
$26.59 $36.88▲ +38.70%▲ +36.84%$25.03 (−5.87%)
Showing 10 of 23

US Market Status

Market Closed — Opens Tue (15h 55m)

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Report published Jun 10, 2026