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Insider Cluster (5 insiders) ·Filed Sep 21, 2026

ORKA

Oruka Therapeutics, Inc.
BEARISH
Impact 5/10
Horizonweeks Processed1mo ago
Insider cluster: 5 insiders, $0.9M total
Actionable Insight ▼ Bearish

The concentrated selling by the entire C-suite, particularly the CEO and CMO, is a bearish signal. Monitor for any upcoming clinical data readouts or corporate developments that may have prompted this selling. The lack of any insider buying alongside the sales reinforces the negative read.

DirectionBearish
Confidencemedium
Horizonweeks
Latest settled — T+20d
ORKA ▼ -16.35% at T+20d
SHORT call ✓ call won +16.35% · α vs SPY +15.79% · entry $94.55 → $79.09
Next anchor: T+60d in 7w
Latest observation: T+23 +15.42% FF3 residual α
Entry = T+0 close
Sep 21, 2026
via day close
T+1d
-4.89%
call +4.89% · α +4.17%
$89.93
settled 5w ago
T+5d
-13.11%
call +13.11% · α +11.93%
$82.15
settled 28d ago
T+20d
-16.35%
call +16.35% · α +15.79%
$79.09
settled 7d ago
T+60d
Pending
in 7w

Price Chart

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Executive Summary

Five Oruka Therapeutics insiders, including the CEO, COO, General Counsel, Chief Medical Officer, and SVP of Finance, executed open-market sales totaling approximately $933K over a one-week window. The CEO's sale of $235K and the CMO's sales of $734K (combined with derivative exercises) are the most notable. This cluster of selling, particularly by the C-suite, signals potential bearish sentiment or a lack of confidence at current elevated price levels, especially given the stock's recent volatility and the company's pre-revenue status.

Key Financial Metrics

Direction
selling
Total Value
$933.0K
Insiders
5

Key Facts

  • 5 insiders sold shares in open-market transactions between Sept 15-21, 2026.
  • Total open-market sales value: ~$933K.
  • CEO Lawrence Klein sold $235K worth of shares.
  • CMO Joana Goncalves sold ~$734K worth of shares, following derivative exercises.
  • COO Laura Sandler sold $87K, General Counsel Paul Quinlan sold $268K, and SVP Arjun Agarwal sold $54K.
  • No open-market purchases were reported in the cluster.
  • The company is a pre-revenue clinical-stage biotech with no approved products.

Financial Impact

Total insider selling of ~$933K represents approximately 0.29% of the company's $326M market cap, which is a modest but notable amount.

market capinsider ownership

Risk Factors

  • Insider selling may indicate management's lack of confidence in near-term stock performance or upcoming catalysts.
  • Pre-revenue biotech companies are highly sensitive to insider sentiment, which can amplify selling pressure.

Investment Themes

Biotech & Drug Discovery

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-ORKA-1790024308429
31 reports for ORKA
Performance horizon
64% Hit rate @ T+5 7 of 11 directional calls Went positive at some point 11 of 11 best @ T+60▲ +80.05%Jun 1, 2026
Filters
Rows
Reports for ORKA — sortable, filterable
TypeNow
Oct 26, 2026
today
8-K
BULLISH ★ 6/10
—awaiting T+5——
Oct 25, 2026
today
Press Release
NEUTRAL ★ 6/10
$80.15awaiting T+5—$89.48 (+11.64%)
Oct 20, 2026
5d ago
Insider Cluster
NEUTRAL ★ 3/10
$79.92awaiting T+5—$89.48 (+11.96%)
Oct 15, 2026
10d ago
Insider Cluster
NEUTRAL ★ 3/10
$71.93 $80.15▲ +11.43%▲ +11.86%$89.48 (+24.40%)
Sep 21, 2026
4w ago
Insider Cluster
BEARISH ★ 5/10
$94.55 $82.15▲ +13.11%▲ +11.93%$89.48 (+5.36%)
Sep 15, 2026
5w ago
Insider Cluster
NEUTRAL ★ 3/10
$93.55 $89.93▼ −3.87%▼ −6.44%$89.48 (−4.35%)
Sep 1, 2026
7w ago
Insider Cluster
BEARISH ★ 4/10
$91.63 $91.65▼ −0.02%▼ −0.98%$89.48 (+2.35%)
Aug 28, 2026
8w ago
EFFECT
BEARISH ★ 6/10
$91.15 $92.51▼ −1.50%▼ −1.39%$89.48 (+1.83%)
Aug 17, 2026
9w ago
Insider Cluster
NEUTRAL ★ 2/10
$113.08 $101.82▼ −9.96%▼ −9.76%$89.48 (−20.87%)
Aug 10, 2026
11w ago
Press Release
BULLISH ★ 7/10
$105.14 $112.66▲ +7.15%▲ +7.20%$89.48 (−14.89%)
Showing 10 of 31

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Report published Sep 21, 2026