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Institutional Cluster ·Filed Sep 22, 2026

OPRX

OptimizeRx Corp
MIXED
Impact 3/10
Horizonweeks Processed1mo ago
Institutional cluster: 13 buyers, 24 sellers (mixed)
Actionable Insight ◆ Mixed

The divergence between active quant buying and mega-passive selling suggests a potential catalyst-driven thesis among informed managers, but the net outflow and lack of insider corroboration warrant caution. Monitor upcoming earnings for any fundamental inflection that could validate the active buying.

DirectionMixed
Confidencemedium
Horizonweeks
Latest settled — T+20d
OPRX ▲ +17.19% at T+20d
NEUTRAL call +17.19% · α vs SPY +17.75% · entry $7.62 → $8.93
Next anchor: T+60d in 7w
Latest observation: T+23 +8.80% FF3 residual α
Entry = T+0 close
Sep 22, 2026
via day close
T+1d
-0.26%
call -0.26% · α +0.46%
$7.60
settled 5w ago
T+5d
+9.71%
call +9.71% · α +10.90%
$8.36
settled 28d ago
T+20d
+17.19%
call +17.19% · α +17.75%
$8.93
settled 7d ago
T+60d
Pending
in 7w

Executive Summary

In Q2 2026, OptimizeRx saw a mixed institutional cluster: 13 buyers (led by Marshall Wace, Morgan Stanley, and Millennium) added $2.2M in new positions, while 24 sellers (led by Goldman Sachs, Geode, and Vanguard) reduced holdings by $5.5M. The net selling pressure of $3.3M, concentrated among mega-passive funds, suggests broad de-risking or index rebalancing, partially offset by conviction buying from active quant and asset managers.

Key Financial Metrics

Direction
distributing
Buy Value
$3.5M
Sell Value
$5.5M
Net Flow
-$3.3M

Institutional Positions

Net institutional flow: -$3.3M

▲ Buyers (13)

InstitutionActionChangePosition ValueValue Δ
Marshall WaceDOUBLED+418.4%$928.0K$731.0K
Morgan StanleyDOUBLED+104.7%$894.0K$415.0K
MillenniumDOUBLED+211.2%$451.0K$292.0K
HSBC HoldingsDOUBLED+343.7%$327.0K$242.0K
Quantinno Capital ManagementDOUBLED+102.2%$567.0K$259.0K

▼ Sellers (24)

InstitutionActionChangePrev ValueValue Δ
Goldman SachsTRIM-70.7%$2.3M-$1.7M
GeodeTRIM-47.1%$2.5M-$1.3M
Vanguard Portfolio ManagementTRIM-48.8%$2.1M-$1.1M
Northern TrustNEAR_EXIT-76.2%$976.0K-$764.0K
FidelityTRIM-66.3%$436.0K-$302.0K

Key Facts

  • 13 institutional buyers added $2.2M in new positions; 24 sellers reduced by $5.5M (net -$3.3M)
  • Marshall Wace doubled its stake to $928K (+$731K); Morgan Stanley doubled to $894K (+$415K); Millennium doubled to $451K (+$292K)
  • Goldman Sachs trimmed 70.7% of its position, selling $1.7M; Geode trimmed 47.1%, selling $1.3M; Vanguard trimmed 48.8%, selling $1.1M
  • Selling was dominated by mega-passive funds (Geode, Goldman, Vanguard, Northern Trust, Fidelity); buying was concentrated among active quant and asset managers (Marshall Wace, Millennium, Susquehanna, HSBC)
  • No insider buying or selling was reported in the confluence data to corroborate the institutional moves

Financial Impact

Net institutional selling of $3.3M in Q2 2026, with $2.2M in buying and $5.5M in selling

institutional ownershipfloat

Risk Factors

  • 13F data has a 45-day reporting lag; positions may have already been reversed
  • Net selling of $3.3M by passive funds could reflect index rebalancing rather than fundamental concerns

Investment Themes

Software & IT

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-OPRX-2026-Q2
13 reports for OPRX
Performance horizon
75% Hit rate @ T+20 3 of 4 directional calls Went positive at some point 3 of 4 best @ T+1▲ +1.48%Mar 5, 2026
Filters
Rows
Reports for OPRX — sortable, filterable
TypeNow
Oct 27, 2026
today
Press Release
NEUTRAL ★ 3/10
$9.15awaiting T+20——
Oct 21, 2026
6d ago
SC 13G/A
NEUTRAL ★ 3/10
$9.37awaiting T+20——
Sep 22, 2026
4w ago
Institutional Cluster
MIXED ★ 3/10
$7.62 $8.93▲ +17.19%▲ +17.75%—
Aug 12, 2026
10w ago
Press Release
BULLISH ★ 6/10
$8.78 $7.29▼ −16.97%▼ −15.22%—
Jun 12, 2026
19w ago
8-K
NEUTRAL ★ 3/10
$5.32 $6.55▲ +23.12%▲ +23.87%—
Jun 11, 2026
19w ago
Institutional Cluster
MIXED ★ 4/10
$5.28 $6.28▲ +18.94%▲ +17.05%—
Jun 5, 2026
20w ago
8-K
NEUTRAL ★ 3/10
$5.05 $6.35▲ +25.74%▲ +24.11%—
Jun 1, 2026
21w ago
DEFA14A
NEUTRAL ★ 3/10
$5.38 $5.72▲ +6.32%▲ +7.62%—
May 21, 2026
22w ago
Press Release
NEUTRAL ★ 4/10
$4.94 $4.70▼ −4.86%▼ −5.19%—
May 12, 2026
23w ago
Press Release
MIXED ★ 6/10
$4.92 $5.28▲ +7.32%▲ +7.93%—
Showing 10 of 13

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Report published Sep 22, 2026