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SC 13G ·Filed Sep 23, 2026

NRIX

Nurix Therapeutics, Inc.
NEUTRAL
Impact 3/10
Horizonweeks Processed1mo ago SEC0001193125-26-399480
Passive investor 5%+ stake
Actionable Insight • Neutral

Perceptive Advisors is a notable healthcare-focused investment firm; a new 5%+ passive stake signals conviction in Nurix's pipeline. Monitor for any subsequent 13D conversion or additional filings that could indicate a shift to activist intent.

DirectionNeutral
Confidencehigh
Horizonweeks
Latest settled — T+20d
NRIX ▲ +7.86% at T+20d
NEUTRAL call +7.86% · α vs SPY +8.28% · entry $23.65 → $25.51
Next anchor: T+60d in 7w
Latest observation: T+21 +6.86% FF3 residual α
Entry = T+0 close
Sep 23, 2026
via day close
T+1d
-2.71%
call -2.71% · α -3.25%
$23.01
settled 5w ago
T+5d
-1.31%
call -1.31% · α -0.90%
$23.34
settled 28d ago
T+20d
+7.86%
call +7.86% · α +8.28%
$25.51
settled 7d ago
T+60d
Pending
in 7w

Price Chart

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Executive Summary

Perceptive Advisors LLC, a healthcare-focused investment firm, filed a Schedule 13G disclosing a 5.3% passive stake in Nurix Therapeutics, Inc. as of September 16, 2026. The stake of 5,536,629 shares is held through the Perceptive Life Sciences Master Fund, Ltd., with Joseph Edelman as the managing member. This is a new passive filing, not an amendment, and the investor certifies no intent to influence control.

Key Financial Metrics

Stake
5.3%
Investor
Perceptive Advisors LLC
Investor Type
hedge fund

Key Facts

  • Perceptive Advisors LLC disclosed a 5.3% beneficial ownership stake in Nurix Therapeutics, Inc.
  • Stake consists of 5,536,629 shares of common stock held by Perceptive Life Sciences Master Fund, Ltd.
  • Filing is a new Schedule 13G, not an amendment, indicating passive investment intent.
  • Joseph Edelman is the managing member of Perceptive Advisors and may be deemed to beneficially own the shares.
  • Ownership percentage based on 103,781,683 shares outstanding as of June 30, 2026.

Financial Impact

5.3% passive stake valued at approximately $5.5 million based on 5,536,629 shares (no per-share price provided in filing).

ownership percentage

Risk Factors

  • Passive 13G filing — no indication of activist intent, but Perceptive could convert to 13D if strategy changes.
  • Biotech sector volatility and clinical-stage pipeline risks remain for Nurix.

Investment Themes

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
SC 13G Filing (Primary)0001193125-26-399480
Document: 0001193125-26-399480-index.html0001193125-26-399480
Document: 0001193125-26-399480.txt0001193125-26-399480
23 reports for NRIX
Performance horizon
60% Hit rate @ T+20 3 of 5 directional calls Went positive at some point 4 of 7 best @ T+20▲ +53.71%Jun 8, 2026
Filters
Rows
Reports for NRIX — sortable, filterable
TypeNow
Oct 15, 2026
12d ago
Insider Cluster
NEUTRAL ★ 3/10
$24.42awaiting T+20—$25.55 (+4.63%)
Oct 14, 2026
13d ago
144
NEUTRAL ★ 2/10
$24.95awaiting T+20—$25.55 (+2.40%)
Oct 13, 2026
14d ago
8-K
BULLISH ★ 7/10
$22.13awaiting T+20—$25.55 (+15.45%)
Oct 5, 2026
22d ago
Press Release
BULLISH ★ 6/10
$22.88awaiting T+20—$25.55 (+11.67%)
Sep 23, 2026
4w ago
SC 13G
NEUTRAL ★ 3/10
$23.65 $25.51▲ +7.86%▲ +8.28%$25.55 (+8.03%)
Sep 2, 2026
7w ago
Insider Cluster
NEUTRAL ★ 2/10
$25.32 $22.99▼ −9.20%▼ −8.01%$25.55 (+0.91%)
Aug 5, 2026
11w ago
Insider Cluster
NEUTRAL ★ 3/10
$25.22awaiting T+20—$25.55 (+1.31%)
Aug 5, 2026
11w ago
Insider Cluster
NEUTRAL ★ 2/10
$25.12awaiting T+20—$25.55 (+1.71%)
Aug 4, 2026
11w ago
Insider Cluster
NEUTRAL ★ 3/10
$25.12awaiting T+20—$25.55 (+1.71%)
Aug 3, 2026
12w ago
Insider Cluster
NEUTRAL ★ 2/10
$24.69awaiting T+20—$25.55 (+3.48%)
Showing 10 of 23

US Market Status

Market Closed — Opens Thu (13h 4m)

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Report published Sep 23, 2026