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PRESS-RELEASE ·Filed May 1, 2026

MPLT

MapLight Therapeutics, Inc.
NEUTRAL
Impact 4/10
Horizonmonths Processed5mo ago WireGlobeNewswire
Press release · FDA
Actionable Insight • Neutral

Monitor for topline data releases by mid-August 2026; positive results would be a major catalyst for MPLT, while negative results could significantly impact the stock. Consider positioning ahead of the data readout.

DirectionNeutral
Confidencehigh
Horizonmonths
Final — all horizons settled through T+60d
MPLT ▼ -59.90% at T+60d
NEUTRAL call -59.90% · α vs SPY -62.97% · entry $30.70 → $12.31
Entry = T+0 close
May 1, 2026
via day close
T+1d
-6.81%
call -6.81% · α -6.47%
$28.61
settled 6mo ago
T+5d
-10.75%
call -10.75% · α -13.10%
$27.40
settled 6mo ago
T+20d
-3.06%
call -3.06% · α -8.35%
$29.76
settled 5mo ago
T+60d
-59.90%
call -59.90% · α -62.97%
$12.31
settled 3mo ago

Price Chart

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Executive Summary

MapLight Therapeutics announced completion of enrollment in the Phase 2 ZEPHYR trial for ML-007C-MA in schizophrenia (307 participants) and the last patient visit in the Phase 2 IRIS trial for ML-004 in autism spectrum disorder (161 participants). Topline results from both trials are expected by mid-August 2026, representing key catalysts for the stock.

Key Facts

  • Enrollment completed in ZEPHYR Phase 2 trial for ML-007C-MA in schizophrenia with 307 participants randomized 1:1:1 to placebo or two doses.
  • Last patient visit completed in IRIS Phase 2 trial for ML-004 in autism spectrum disorder with 161 participants randomized.
  • Topline results from both Phase 2 trials expected by mid-August 2026.

Financial Impact

Not specified

Risk Factors

  • Clinical trial failure or disappointing efficacy/safety data.
  • Regulatory delays or unfavorable risk-benefit profile.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
91% bullish (11 analysts)

Investment Themes

Documents Analyzed

This report is based on 1 press release from GlobeNewswire.

DocumentAccession Number
PRESS-RELEASE Data (Synthetic)press-3285832
31 reports for MPLT
Performance horizon
67% Hit rate @ T+20 4 of 6 directional calls Went positive at some point 6 of 7 best @ T+60▲ +57.24%May 18, 2026
Filters
Rows
Reports for MPLT — sortable, filterable
TypeNow
Oct 16, 2026
10d ago
Insider Cluster
BEARISH ★ 4/10
$8.00awaiting T+20—$7.66 (+4.25%)
Oct 15, 2026
11d ago
144
NEUTRAL ★ 2/10
$7.70awaiting T+20—$7.66 (−0.52%)
Oct 15, 2026
11d ago
144
NEUTRAL ★ 2/10
$7.70awaiting T+20—$7.66 (−0.52%)
Oct 15, 2026
11d ago
144
NEUTRAL ★ 2/10
$7.70awaiting T+20—$7.66 (−0.52%)
Sep 24, 2026
4w ago
EFFECT
NEUTRAL ★ 4/10
$10.76 $8.25▼ −23.33%▼ −22.91%$7.66 (−28.81%)
Sep 18, 2026
5w ago
S-1/A
NEUTRAL ★ 4/10
$10.90 $8.00▼ −26.61%▼ −25.70%$7.66 (−29.72%)
Aug 4, 2026
11w ago
Insider Cluster
BULLISH ★ 7/10
$12.92 $13.06▲ +1.08%▲ +1.69%$7.66 (−40.71%)
Aug 3, 2026
12w ago
144
NEUTRAL ★ 2/10
$12.94 $13.31▲ +2.86%▲ +4.10%$7.66 (−40.80%)
Jul 30, 2026
12w ago
144
BEARISH ★ 5/10
$13.02 $12.60▲ +3.23%▲ +6.21%$7.66 (+41.17%)
Jul 28, 2026
12w ago
Insider Buy
NEUTRAL ★ 3/10
$15.02 $12.86▼ −14.38%▼ −19.40%$7.66 (−49.00%)
Showing 10 of 31

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Report published May 1, 2026