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8-K ·Filed May 29, 2026

MNPR

Monopar Therapeutics
NEUTRAL
Impact 4/10
Horizonweeks Processed5mo ago SEC0001437749-26-018896
8-K context-dependent: Items 7.01
Actionable Insight • Neutral

Monitor for follow-up disclosures or peer-reviewed publications detailing the magnitude and statistical significance of the Phase 2 ALXN1840 results, which could inform the drug's probability of advancing to Phase 3. Without concrete efficacy or safety data in this filing, the stock impact is likely muted and event-driven.

DirectionNeutral
Confidencehigh
Horizonweeks
Final: all horizons settled through T+60d
MNPR ▲ +72.08% at T+60d
NEUTRAL call +72.08% · α vs SPY +70.85% · entry $64.40 → $110.82
Entry = T+0 close
May 29, 2026
via day close
T+1d
-4.88%
call -4.88% · α -5.02%
$61.26
settled 5mo ago
T+5d
-7.64%
call -7.64% · α -4.89%
$59.48
settled 5mo ago
T+20d
+43.77%
call +43.77% · α +45.07%
$92.59
settled 4mo ago
T+60d
+72.08%
call +72.08% · α +70.85%
$110.82
settled 2mo ago

Price Chart

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Executive Summary

Monopar Therapeutics presented Phase 2 study results for ALXN1840 (tiomolibdate choline) in Wilson disease at the EASL International Liver Congress 2026. The presentation was disclosed via an 8-K under Item 7.01 (Regulation FD Disclosure) and furnished as Exhibit 99.1, which is an image-based file without extractable quantitative clinical data. This is a routine disclosure of a scientific presentation at a medical conference, not a definitive regulatory or financial milestone.

Key Facts

  • Phase 2 study (NCT04422431) results for ALXN1840 in Wilson disease were presented at EASL 2026
  • Presentation disclosed via 8-K Item 7.01 on May 29, 2026
  • Exhibit 99.1 is an image-based presentation without extractable quantitative endpoints
  • No financial guidance, revenue data, or capital allocation changes were included
  • ALXN1840 was originally developed by Alexion/AstraZeneca; Monopar's current rights or development path are not described

Financial Impact

No financial figures were disclosed in the filing

Risk Factors

  • Phase 2 results may not meet efficacy thresholds for advancement to Phase 3
  • Wilson disease is a niche indication with limited commercial upside
  • Monopar's rights to ALXN1840 and development timeline remain unclear from this filing

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
95% bullish (20 analysts)

Investment Themes

Documents Analyzed

This report is based on 4 SEC documents filed with EDGAR.

DocumentAccession Number
8-K Filing (Primary)0001437749-26-018896
Document: 0001437749-26-018896-index-headers.html0001437749-26-018896
Document: 0001437749-26-018896-index.html0001437749-26-018896
Document: 0001437749-26-018896.txt0001437749-26-018896
22 reports for MNPR
Performance horizon
70% Hit rate @ T+60 7 of 10 directional calls Went positive at some point 13 of 13 best @ T+60▲ +98.70%Apr 19, 2026
Filters
Rows
Reports for MNPR, sortable and filterable
TypeNow
Oct 27, 2026
today
Institutional Cluster
MIXED ★ 3/10
$72.00awaiting T+60awaiting T+60$71.84 (−0.22%)
Oct 27, 2026
today
SC 13G
NEUTRAL ★ 3/10
$72.00awaiting T+60awaiting T+60$71.84 (−0.22%)
Oct 5, 2026
22d ago
Insider Cluster
BEARISH ★ 4/10
$79.57awaiting T+60awaiting T+60$71.84 (+9.71%)
Oct 1, 2026
26d ago
144
NEUTRAL ★ 3/10
$77.97awaiting T+60awaiting T+60$71.84 (−7.86%)
Aug 28, 2026
8w ago
Insider Cluster
NEUTRAL ★ 2/10
$111.93awaiting T+60awaiting T+60$71.84 (−35.82%)
Aug 27, 2026
8w ago
Insider Cluster
NEUTRAL ★ 3/10
$111.89awaiting T+60awaiting T+60$71.84 (−35.79%)
Aug 25, 2026
9w ago
144
NEUTRAL ★ 3/10
$113.72awaiting T+60awaiting T+60$71.84 (−36.83%)
Aug 12, 2026
10w ago
8-K
BULLISH ★ 6/10
$114.90awaiting T+60awaiting T+60$71.84 (−37.48%)
Aug 12, 2026
10w ago
Press Release
BULLISH ★ 6/10
$114.90awaiting T+60awaiting T+60$71.84 (−37.48%)
Jul 22, 2026
13w ago
8-K
BULLISH ★ 6/10
$112.48 $71.80▼ −36.17%▼ −39.43%$71.84 (−36.13%)
Showing 10 of 22

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Report published May 29, 2026