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PRESS-RELEASE ·Filed May 5, 2026

MCRB

Seres Therapeutics, Inc.
BEARISH
Impact 7/10
Horizonweeks Processed5mo ago WireGlobeNewswire
Press release · Earnings
Actionable Insight ▼ Bearish

Cash runway through Q3 2026 creates urgent financing overhang. The SER-155 irEC data readout in coming weeks is the key binary catalyst — positive data could extend runway via partnership/licensing; negative data would accelerate distress. Monitor for equity offering, partnership announcement, or going concern disclosure in next 10-Q.

DirectionBearish
Confidencehigh
Horizonweeks
Final — all horizons settled through T+60d
MCRB ▼ -36.27% at T+60d
SHORT call ✓ call won +36.27% · α vs SPY +39.01% · entry $7.50 → $4.78
Entry = T+0 close
May 5, 2026
via day close
T+1d
+6.67%
call -6.67% · α -5.28%
$8.00
settled 6mo ago
T+5d
+4.53%
call -4.53% · α -2.55%
$7.84
settled 6mo ago
T+20d
-2.27%
call +2.27% · α +7.22%
$7.33
settled 5mo ago
T+60d
-36.27%
call +36.27% · α +39.01%
$4.78
settled 3mo ago

Price Chart

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Executive Summary

Seres Therapeutics reported Q1 2026 net loss of $19.9M vs net income of $32.7M in Q1 2025 (which included a $50M Nestlé milestone payment). EPS of -$2.08 beat consensus of -$1.88 by 5.3%, but revenue was negligible at $358K (grant revenue only). Cash runway extends only through Q3 2026, and the company is actively seeking partnerships and financing to fund pipeline programs including SER-155 (Phase 2 ready) and SER-603 (IND-enabling).

Key Financial Metrics

EPS
−$2.08
est −$1.88 · -10.6%
Revenue
$358.0K
est $0.00
Rating
miss

Key Facts

  • Q1 2026 net loss $19.9M vs net income $32.7M in Q1 2025 (which included $50M Nestlé milestone payment)
  • EPS -$2.08 beat consensus -$1.88 by 5.3%
  • Revenue $358K (grant revenue only) vs $0 consensus; no product revenue
  • Cash and equivalents $29.8M as of March 31, 2026; expects to fund operations only through Q3 2026
  • Operating expenses $21.3M, down ~$6M YoY due to completion of Nestlé transition services
  • SER-155 Phase 2 ready for allo-HSCT but seeking funding to commence study
  • Investigator-sponsored SER-155 study in irEC (15 patients enrolled) data expected in coming weeks
  • SER-603 IND-enabling activities ongoing for IBD
  • Going concern risk: cash runway only through Q3 2026 with no clear financing source
  • Accumulated deficit $992.3M

Financial Impact

Net loss $19.9M; cash burn rate ~$5M/month; cash runway through Q3 2026 only

revenuenet incomecash runwayoperating expenses

Risk Factors

  • Cash runway only through Q3 2026 — going concern risk if no financing secured
  • No product revenue; fully dependent on pipeline milestones and external funding
  • SER-155 irEC study is small (n=15) — data may be inconclusive
  • Potential dilutive equity offering to extend cash runway
  • Nasdaq continued listing risk (market cap $74M, potential minimum bid price issues)

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
86% bullish (7 analysts)

Investment Themes

Documents Analyzed

This report is based on 1 press release from GlobeNewswire.

DocumentAccession Number
PRESS-RELEASE Data (Synthetic)press-3287503
12 reports for MCRB
Performance horizon
75% Hit rate @ T+20 3 of 4 directional calls Went positive at some point 3 of 4 best @ T+60▲ +36.27%May 5, 2026
Filters
Rows
Reports for MCRB — sortable, filterable
TypeNow
Oct 26, 2026
today
8-K
BEARISH ★ 5/10
$1.98awaiting T+20—$1.80 (+9.09%)
Aug 24, 2026
9w ago
EFFECT
BEARISH ★ 5/10
$4.66 $4.02▲ +13.73%▲ +15.05%$1.80 (+61.37%)
Aug 5, 2026
11w ago
8-K
BULLISH ★ 6/10
$5.01 $5.54▲ +10.69%▲ +11.29%$1.80 (−64.04%)
Jul 8, 2026
15w ago
8-K
BULLISH ★ 7/10
$7.14 $5.01▼ −29.90%▼ −33.17%$1.80 (−74.79%)
Jun 5, 2026
20w ago
8-K
MIXED ★ 6/10
$6.63 $7.71▲ +16.29%▲ +14.43%$1.80 (−72.85%)
Jun 5, 2026
20w ago
Press Release
NEUTRAL ★ 5/10
$6.63 $7.71▲ +16.29%▲ +14.43%$1.80 (−72.85%)
May 19, 2026
23w ago
Insider Cluster
NEUTRAL ★ 2/10
$7.66 $6.61▼ −13.71%▼ −14.45%$1.80 (−76.50%)
May 5, 2026
25w ago
8-K
BEARISH ★ 7/10
$7.50 $7.33▲ +2.27%▲ +7.22%$1.80 (+76.00%)
May 5, 2026
25w ago
Press Release
BEARISH ★ 7/10
$7.50 $7.33▲ +2.27%▲ +7.22%$1.80 (+76.00%)
May 4, 2026
25w ago
Press Release
NEUTRAL ★ 3/10
$7.69 $7.64▼ −0.65%▼ −6.30%$1.80 (−76.59%)
Showing 10 of 12

US Market Status

Market Closed — Opens Wed (17h 19m)

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Report published May 5, 2026