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Institutional Cluster

MBX

MBX Biosciences, Inc.
NEUTRAL
Impact 4/10
Horizonweeks Processed8mo ago
Institutional cluster: 3 buyers, 0 sellers (bullish)
Actionable Insight • Neutral

Monitor whether active managers join this trend in the next quarter; currently, the buying is limited to passive players, so it may not signal strong fundamental optimism. However, increased passive ownership could improve liquidity and index inclusion tailwinds.

DirectionNeutral
Confidencehigh
Horizonweeks
Final — all horizons settled through T+60d ⚠ clustered
MBX ▼ -3.70% at T+60d
NEUTRAL call -3.70% · α vs SPY -13.03% · entry $32.97 → $31.75
Entry = T+0 close
Feb 28, 2026
via day close
T+1d
-7.37%
call -7.37% · α -6.46%
$30.54
settled 8mo ago
T+5d
-15.26%
call -15.26% · α -14.05%
$27.94
settled 8mo ago
T+20d
-18.35%
call -18.35% · α -10.41%
$26.92
settled 7mo ago
T+60d
-3.70%
call -3.70% · α -13.03%
$31.75
settled 5mo ago

Executive Summary

Three major passive institutional investors — Morgan Stanley, Wells Fargo, and Schwab — initiated new positions in MBX Biosciences during Q4 2024, collectively purchasing $2.3M in shares. This represents a coordinated entry by large financial intermediaries, though all are classified as mega-passive funds, suggesting the moves may reflect index or model portfolio adjustments rather than active conviction. The cluster is entirely on the buy side with no selling activity, indicating no institutional exits during the quarter.

Key Financial Metrics

Direction
accumulating
Buy Value
$2.3M
Net Flow
$2.3M

Institutional Positions

Net institutional flow: $2.3M

▲ Buyers (3)

InstitutionActionChangePosition ValueValue Δ
SchwabNEW+0%$1.7M$1.7M
Morgan StanleyNEW+0%$439.0K$439.0K
Wells FargoNEW+0%$108.0K$108.0K

Key Facts

  • 3 mega-passive institutions initiated new positions in MBX during Q4 2024
  • Total institutional buying amounted to $2.3M with no offsetting seller activity
  • Schwab established the largest position at $1.7M, followed by Morgan Stanley at $439K and Wells Fargo at $108K
  • All buyers are categorized as mega-passive, indicating likely index-driven or model-based allocation rather than active fundamental research

Financial Impact

Institutions accumulated $2.3M in new positions with no selling

floatinstitutional ownershipliquidity

Risk Factors

  • Passive buying does not reflect fundamental conviction and may not support the stock during downturns
  • Lack of participation from active or specialized biotech investors suggests limited catalyst-driven interest

Market Snapshot

Exchange
Nasdaq

Investment Themes

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-MBX-2024-Q4
27 reports for MBX
Performance horizon
70% Hit rate @ T+1 7 of 10 directional calls Went positive at some point 8 of 10 best @ T+60▲ +85.57%May 7, 2026
Filters
Rows
Reports for MBX — sortable, filterable
TypeNow
Oct 22, 2026
4d ago
3
NEUTRAL ★ 2/10
$50.46 $48.50▼ −3.88%▼ −3.36%—
Oct 22, 2026
4d ago
8-K
NEUTRAL ★ 2/10
$50.46 $48.50▼ −3.88%▼ −3.36%—
Aug 27, 2026
8w ago
Press Release
BULLISH ★ 8/10
$66.39 $63.00▼ −5.11%▼ −4.88%—
Aug 17, 2026
10w ago
144
NEUTRAL ★ 3/10
$68.25 $66.52▼ −2.53%▼ −1.86%—
Aug 6, 2026
11w ago
8-K
BULLISH ★ 7/10
$67.11 $67.82▲ +1.06%▲ +0.45%—
Jun 12, 2026
19w ago
8-K
BULLISH ★ 7/10
$35.51 $38.98▲ +9.77%▲ +8.01%—
Jun 12, 2026
19w ago
Press Release
BULLISH ★ 6/10
$35.51 $38.98▲ +9.77%▲ +8.01%—
Jun 11, 2026
19w ago
Institutional Cluster
BULLISH ★ 5/10
$37.25 $35.51▼ −4.67%▼ −5.21%—
Jun 11, 2026
19w ago
Institutional Cluster
NEUTRAL ★ 3/10
$37.25 $35.51▼ −4.67%▼ −5.21%—
Jun 10, 2026
19w ago
144
NEUTRAL ★ 2/10
$30.99 $37.25▲ +20.20%▲ +18.50%—
Showing 10 of 27

US Market Status

Market Closed — Opens Tue (16h 37m)

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Report published Feb 28, 2026