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EFFECT ·Filed Oct 23, 2026
LY

LYCA

Lycia Therapeutics, Inc.
BULLISH
Impact 7/10
Horizonimmediate Processed4d 4h ago SEC9999999995-26-003321
IPO/offering going effective
Actionable Insight ▲ Bullish

IPO pricing is imminent — likely within 1-2 trading days. Watch for the final IPO price and first-day trading performance. The LYTAC platform targeting autoimmune/inflammatory diseases is novel but pre-revenue; initial float and institutional demand will set the tone. Monitor for post-IPO lockup expiration (typically 180 days) and any early insider registration statements.

DirectionBullish
Confidencehigh
Horizonimmediate
Latest settled — T+1d ⚠ clustered
LYCA ▼ -3.83% at T+1d
LONG call ✗ call lost -3.83% · α vs SPY -4.54% · entry $30.00 → $28.85
Next anchor: T+5d in 3d
Entry = T+0 close
Oct 23, 2026
via day close
T+1d
-3.83%
call -3.83% · α -4.54%
$28.85
settled 21h ago
T+5d
Pending
in 3d
T+20d
Pending
in 24d
T+60d
Pending
in 3mo

Price Chart

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Executive Summary

Lycia Therapeutics' IPO registration (S-1, File No. 333-299300) became effective on October 22, 2026. The company is now cleared to begin trading on Nasdaq under ticker LYCA, offering 14,700,000 shares at an expected price range of $16.00-$18.00 per share, with an underwriter option for an additional 2,205,000 shares. This marks the transition from a private clinical-stage biotech to a public company, with pricing expected imminently.

Key Facts

  • IPO registration declared effective on October 22, 2026
  • Offering 14,700,000 shares of common stock
  • Expected IPO price range: $16.00 to $18.00 per share
  • Underwriters granted 30-day option to purchase up to 2,205,000 additional shares
  • Listing on Nasdaq Global Select Market under ticker LYCA
  • Joint book-running managers: Jefferies, TD Cowen, Evercore ISI, Guggenheim Securities
  • Passive book-running manager: LifeSci Capital
  • Company is a clinical-stage biotech focused on extracellular protein degradation (LYTAC platform)

Financial Impact

IPO expected to raise approximately $235-265 million before expenses (14.7M shares × $16-18 midpoint), plus up to ~$35-40 million from the overallotment option if exercised in full

dilutioncashmarketCap

Risk Factors

  • Pre-revenue clinical-stage biotech with no approved products
  • Expected IPO price range is wide ($16-$18) and final pricing may vary
  • No public market exists yet — first-day volatility could be significant
  • Underwriters' overallotment option adds 15% dilution if exercised
  • Lockup expiration (standard 180 days) could pressure shares post-IPO

Market Snapshot

Exchange
Nasdaq

Investment Themes

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
EFFECT Filing (Primary)9999999995-26-003321
Document: 9999999995-26-003321-index.html9999999995-26-003321
Document: 9999999995-26-003321.txt9999999995-26-003321
3 reports for LYCA
Performance horizon
Filters
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Reports for LYCA — sortable, filterable
TypeNow
Oct 26, 2026
today
Press Release
NEUTRAL ★ 5/10
$28.85awaiting T+1—$28.85 (+0.00%)
Oct 23, 2026
3d ago
424B4
NEUTRAL ★ 5/10
$28.11awaiting T+1—$28.85 (+2.63%)
Oct 23, 2026
4d ago
EFFECT
BULLISH ★ 7/10
$30.00 $28.85▼ −3.83%▼ −4.54%$28.85 (−3.83%)
Showing 3 of 3

US Market Status

Market Closed — Opens in 4h 20m

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Report published Oct 23, 2026