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Institutional Cluster ·Filed Sep 22, 2026

GRAL

GRAIL, Inc.
MIXED
Impact 4/10
Horizonweeks Processed1mo ago
Institutional cluster: 35 buyers, 21 sellers (mixed)
Actionable Insight ◆ Mixed

The divergence between mega-passive accumulators and active/quant sellers suggests passive index rebalancing or systematic factor exposure rather than a fundamental catalyst. Monitor next 10-Q for revenue/progress updates on Galleri test adoption and reimbursement expansion, which would validate or refute the passive accumulation thesis.

DirectionMixed
Confidencemedium
Horizonweeks
Latest settled — T+20d
GRAL ▲ +14.88% at T+20d
NEUTRAL call +14.88% · α vs SPY +15.44% · entry $108.52 → $124.67
Next anchor: T+60d in 7w
Latest observation: T+23 +14.88% FF3 residual α
Entry = T+0 close
Sep 22, 2026
via day close
T+1d
0.00%
call 0.00% · α +0.72%
$108.52
settled 5w ago
T+5d
+25.85%
call +25.85% · α +27.03%
$136.57
settled 28d ago
T+20d
+14.88%
call +14.88% · α +15.44%
$124.67
settled 7d ago
T+60d
Pending
in 7w

Executive Summary

GRAIL, Inc. (GRAL) saw a mixed institutional cluster in Q2 2026, with 35 buyers accumulating $91.3M in net new positions (total holdings $179.9M) while 21 sellers reduced by $19.0M. The buying is dominated by mega-passive and asset managers (Dimensional, Goldman Sachs, Vanguard, Fidelity, Wells Fargo, UBS) adding significant positions, while notable quant and hedge fund sellers (RenTech, Susquehanna, Marshall Wace, BNP Paribas) trimmed or nearly exited. The net $72.3M inflow suggests institutional interest is growing, but the divergence between passive accumulators and active/quant sellers creates an ambiguous signal.

Key Financial Metrics

Direction
mixed
Buy Value
$179.9M
Sell Value
$19.0M
Net Flow
$72.3M

Institutional Positions

Net institutional flow: $72.3M

▲ Buyers (35)

InstitutionActionChangePosition ValueValue Δ
Dimensional Fund AdvisorsADD+66.3%$46.4M$25.3M
Goldman SachsADD+28.5%$51.1M$21.0M
Vanguard Portfolio ManagementADD+42.7%$32.6M$15.3M
Wells FargoDOUBLED+402.4%$13.3M$11.3M
UBSADD+34.7%$17.1M$7.5M
FidelityDOUBLED+125.1%$8.7M$5.7M
D.E. ShawADD+42.3%$7.9M$3.7M

▼ Sellers (21)

InstitutionActionChangePrev ValueValue Δ
BNP Paribas Financial MarketsNEAR_EXIT-79%$7.7M-$5.6M
Susquehanna International GroupTRIM-49.1%$15.8M-$5.2M
Victory Capital ManagementNEAR_EXIT-92.1%$3.0M-$2.7M
Marshall WaceNEAR_EXIT-89.6%$3.1M-$2.7M
RenTechNEAR_EXIT-83.3%$2.9M-$2.2M

Key Facts

  • 35 institutional buyers added $91.3M in net new positions, bringing total buyer holdings to $179.9M
  • 21 institutional sellers reduced holdings by $19.0M
  • Top buyers: Dimensional Fund Advisors (+$25.3M to $46.4M), Goldman Sachs (+$21.0M to $51.1M), Vanguard (+$15.3M to $32.6M)
  • Top sellers: Susquehanna (-$5.2M to $10.6M), BNP Paribas (-$5.6M to $2.1M), Victory Capital (-$2.7M to $313K), Marshall Wace (-$2.7M to $423K), RenTech (-$2.2M to $628K)
  • Mega-passive funds (Goldman, Fidelity, Wells Fargo, UBS) were the dominant buyers, while quant/active managers (RenTech, Susquehanna, Marshall Wace) were the dominant sellers
  • Net institutional inflow of approximately $72.3M

Financial Impact

Net institutional inflow of approximately $72.3M in Q2 2026, with $91.3M in buying vs $19.0M in selling. Buyer holdings total $179.9M.

institutional_ownershipfloat_percentage

Risk Factors

  • 13F data has 45-day reporting lag; positions may have been unwound since quarter-end
  • Dominance of mega-passive buyers (Goldman, Fidelity, Wells Fargo, UBS) suggests index rebalancing rather than fundamental conviction
  • Active/quant sellers (RenTech, Susquehanna, Marshall Wace) reducing positions is a contrarian signal against the passive buying

Investment Themes

Healthcare & Medical Devices

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-GRAL-2026-Q2
9 reports for GRAL
Performance horizon
60% Hit rate @ T+20 3 of 5 directional calls Went positive at some point 4 of 5 best @ T+60▲ +33.54%Jun 11, 2026
Filters
Rows
Reports for GRAL — sortable, filterable
TypeNow
Oct 21, 2026
5d ago
Press Release
NEUTRAL ★ 1/10
$127.06awaiting T+20——
Sep 23, 2026
4w ago
Insider Cluster
BEARISH ★ 4/10
$125.21 $127.06▼ −1.48%▼ −1.90%—
Sep 22, 2026
5w ago
Institutional Cluster
MIXED ★ 4/10
$108.52 $124.67▲ +14.88%▲ +15.44%—
Aug 31, 2026
8w ago
Insider Cluster
NEUTRAL ★ 2/10
$79.79 $140.12▲ +75.61%▲ +75.29%—
Jun 11, 2026
19w ago
Institutional Cluster
BULLISH ★ 6/10
$60.16 $75.79▲ +25.98%▲ +24.09%—
Apr 28, 2026
25w ago
DEFA14A
NEUTRAL ★ 2/10
$49.69 $73.92▲ +48.76%▲ +42.71%—
Apr 8, 2026
28w ago
Insider Cluster
BEARISH ★ 7/10
$50.78 $54.40▼ −7.13%▲ +1.42%—
Mar 2, 2026
34w ago
Insider Cluster
BEARISH ★ 7/10
$52.63 $46.90▲ +10.89%▲ +2.95%—
Mar 2, 2026
34w ago
Insider Cluster
BEARISH ★ 7/10
$52.63 $46.90▲ +10.89%▲ +2.95%—
Showing 9 of 9

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Report published Sep 22, 2026