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Institutional Cluster ·Filed Oct 12, 2026

DNTH

Dianthus Therapeutics, Inc. /DE/
MIXED
Impact 3/10
Horizonweeks Processed14d 15h ago
Institutional cluster: 48 buyers, 24 sellers (mixed)
Actionable Insight ◆ Mixed

The divergence between passive accumulation and active/quant selling is stark. Monitor next earnings for fundamental catalysts that could justify the quant exodus or prove them wrong. The Pictet doubling is an outlier — watch for follow-on 13F filings to see if other active managers join.

DirectionMixed
Confidencemedium
Horizonweeks
Latest settled — T+5d
DNTH ▼ -8.62% at T+5d
NEUTRAL call -8.62% · α vs SPY -7.13% · entry $81.57 → $74.54
Next anchor: T+20d in 13d
Latest observation: T+9 -1.92% FF3 residual α
Entry = T+0 close
Oct 12, 2026
via day close
T+1d
-4.89%
call -4.89% · α -4.88%
$77.58
settled 14d ago
T+5d
-8.62%
call -8.62% · α -7.13%
$74.54
settled 8d ago
T+20d
Pending
in 13d
T+60d
Pending
in 2mo

Executive Summary

Q2 2026 13F filings reveal a mixed institutional cluster in Dianthus Therapeutics (DNTH): 48 buyers added $170.9M in positions (dominated by mega-passive funds like Geode, UBS, and Vanguard), while 24 sellers reduced by $126.7M, including full exits by quant funds Point72 and Millennium. The net $44.2M inflow is driven by passive/index rebalancing, not active conviction, while the aggressive selling by sophisticated quant shops signals caution on the stock's outlook.

Key Financial Metrics

Direction
mixed
Buy Value
$390.5M
Sell Value
$126.7M
Net Flow
$44.2M

Institutional Positions

Net institutional flow: $44.2M

▲ Buyers (48)

InstitutionActionChangePosition ValueValue Δ
GeodeADD+37.4%$122.7M$45.8M
UBSADD+45.9%$111.2M$45.6M
Vanguard Portfolio ManagementADD+63.2%$55.6M$26.3M
Pictet Asset ManagementDOUBLED+4922.2%$24.1M$23.7M

▼ Sellers (24)

InstitutionActionChangePrev ValueValue Δ
Point72EXIT-100%$54.0M-$54.0M
MillenniumTRIM-64.9%$22.0M-$13.0M
D.E. ShawTRIM-71.3%$12.6M-$8.4M
Bnp ParibasNEAR_EXIT-96.5%$19.8M-$19.0M

Key Facts

  • 48 institutional buyers added $170.9M in new positions during Q2 2026
  • 24 institutional sellers reduced holdings by $126.7M, net inflow of $44.2M
  • Top buyers: Geode (+$45.8M), UBS (+$45.6M), Vanguard (+$26.3M) — all mega-passive/index funds
  • Point72 fully exited a $54.0M position; Millennium trimmed -64.9% ($13.0M); D.E. Shaw trimmed -71.3% ($8.4M)
  • Pictet Asset Management nearly doubled its position from $413K to $24.1M (+4922%) — the only active manager with conviction buying
  • Passive/index funds account for ~85% of buying value; active managers are net sellers

Financial Impact

48 buyers accumulated $390.5M in holdings (net change +$170.9M) while 24 sellers reduced by $126.7M, for a net institutional inflow of $44.2M in Q2 2026

institutional ownershipfloat

Risk Factors

  • 13F data is 45+ days stale; positions may have already been unwound
  • Quant funds (Point72, Millennium, D.E. Shaw) exiting suggests thesis concerns not visible in passive buying
  • Passive buying may reflect index rebalancing, not stock-specific conviction — not a directional signal

Investment Themes

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-DNTH-2026-Q2
17 reports for DNTH
Performance horizon
88% Hit rate @ T+1 7 of 8 directional calls Went positive at some point 8 of 8 best @ T+60▲ +41.40%Jun 11, 2026
Filters
Rows
Reports for DNTH — sortable, filterable
TypeNow
Oct 12, 2026
14d ago
Institutional Cluster
MIXED ★ 3/10
$81.57 $77.58▼ −4.89%▼ −4.88%—
Aug 11, 2026
10w ago
Insider Cluster
NEUTRAL ★ 4/10
$112.41 $109.60▼ −2.50%▼ −3.20%—
Aug 11, 2026
10w ago
Insider Cluster
NEUTRAL ★ 3/10
$112.41 $109.60▼ −2.50%▼ −3.20%—
Aug 11, 2026
10w ago
Insider Cluster
NEUTRAL ★ 3/10
$112.41 $109.60▼ −2.50%▼ −3.20%—
Aug 11, 2026
10w ago
Insider Cluster
BEARISH ★ 6/10
$112.41 $109.60▲ +2.50%▲ +3.20%—
Aug 10, 2026
11w ago
144
NEUTRAL ★ 2/10
$108.49 $112.41▲ +3.61%▲ +3.36%—
Jun 29, 2026
17w ago
Press Release
BULLISH ★ 5/10
$95.68 $97.48▲ +1.88%▲ +1.10%—
Jun 12, 2026
19w ago
8-K
BULLISH ★ 7/10
$82.07 $82.51▲ +0.54%▼ −1.23%—
Jun 11, 2026
19w ago
Institutional Cluster
BULLISH ★ 5/10
$76.45 $82.07▲ +7.35%▲ +6.81%—
May 5, 2026
24w ago
8-K
BULLISH ★ 7/10
$90.42 $85.47▼ −5.47%▼ −5.14%—
Showing 10 of 17

US Market Status

Market Closed — Opens in 9h 29m

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Report published Oct 12, 2026