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20-F ·Filed Apr 27, 2026

CUPR

Cuprina Holdings (Cayman) LTD
BEARISH
Impact 6/10
Horizonmonths Processed6mo ago SEC0001493152-26-019085
Notable filing: 20-F
Actionable Insight ▼ Bearish

Monitor the company's ability to control professional fees and manage cash burn, as the $7.1 million operating cash outflow raises sustainability concerns. Watch for progress on Nasdaq compliance following the recent AGM proposals, as failure to regain compliance could trigger delisting. The lack of patent protection for the MEDIFLY product, which generated 88.6% of 2025 revenue, represents a critical competitive vulnerability that investors should closely monitor.

DirectionBearish
Confidencehigh
Horizonmonths
Final — all horizons settled through T+60d
CUPR ▲ +41.27% at T+60d
SHORT call ✗ call lost -41.27% · α vs SPY -36.49% · entry $2.34 → $3.30
Entry = T+0 close
Apr 27, 2026
via day close
T+1d
-2.40%
call +2.40% · α +1.91%
$2.28
settled 6mo ago
T+5d
-10.62%
call +10.62% · α +11.01%
$2.09
settled 6mo ago
T+20d
-16.10%
call +16.10% · α +21.05%
$1.96
settled 5mo ago
T+60d
+41.27%
call -41.27% · α -36.49%
$3.30
settled 3mo ago

Price Chart

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Executive Summary

Cuprina Holdings reported a significant increase in net loss to $3.63 million in 2025, primarily due to a $3.1 million increase in operating expenses, particularly a $3.2 million surge in professional fees. Despite a modest 3.3% revenue increase driven by its MEDIFLY maggot therapy product, the company faces substantial challenges including lack of patent protection for its core product, significant working capital outflows, and ongoing Nasdaq compliance risks. Recent regulatory progress in Saudi Arabia and pipeline development in medical waste recycling and IVF media provide some strategic momentum.

Key Facts

  • Net loss increased 198% from $1.56M in 2024 to $3.63M in 2025
  • Revenue increased 3.3% from $48.3K to $49.9K, driven by MEDIFLY product sales
  • Operating expenses surged 194% to $4.83M, with professional fees increasing by $3.2M
  • Core MEDIFLY product has no patent protection, relying solely on trade secrets
  • Net cash used in operating activities was $7.1M, a 478% increase from 2024
  • Recent 6-K filings show company is addressing Nasdaq listing compliance through share consolidation

Financial Impact

Net loss increased by $2.11 million (198%) from 2024 to 2025, driven by a $3.1 million increase in professional fees and other operating expenses

net lossoperating expensescash flow from operations

Risk Factors

  • Lack of patent protection for core MEDIFLY product makes it vulnerable to competition
  • Significant cash burn from operations ($7.1M) threatens liquidity
  • Nasdaq listing compliance at risk due to minimum bid price requirement
  • Heavy reliance on professional fees ($3.2M increase) indicates high corporate costs

Market Snapshot

Exchange
Nasdaq
Sector
Orthopedic, Prosthetic & Surgical Appliances & Supplies

Investment Themes

Healthcare & Medical Devices

Documents Analyzed

This report is based on 8 SEC documents filed with EDGAR.

DocumentAccession Number
20-F Filing (Primary)0001493152-26-019085
Exhibit: ex12-2.htm0001493152-26-019085
Exhibit: ex12-1.htm0001493152-26-019085
Exhibit: ex13-2.htm0001493152-26-019085
Exhibit: ex13-1.htm0001493152-26-019085
Document: 0001493152-26-019085-index-headers.html0001493152-26-019085
Document: 0001493152-26-019085-index.html0001493152-26-019085
Document: 0001493152-26-019085.txt0001493152-26-019085
18 reports for CUPR
Performance horizon
25% Hit rate @ T+5 3 of 12 directional calls Went positive at some point 3 of 13 best @ T+20▲ +46.35%Sep 11, 2026
Filters
Rows
Reports for CUPR — sortable, filterable
TypeNow
Oct 20, 2026
7d ago
6-K
BEARISH ★ 7/10
$1.93awaiting T+5—$1.85 (+4.15%)
Oct 2, 2026
25d ago
6-K
BULLISH ★ 6/10
$2.42 $1.69▼ −30.17%▼ −31.33%$1.85 (−23.55%)
Oct 2, 2026
25d ago
Press Release
MIXED ★ 5/10
$2.42 $1.69▼ −30.17%▼ −31.33%$1.85 (−23.55%)
Sep 29, 2026
28d ago
6-K
BEARISH ★ 5/10
$2.28 $1.99▲ +12.72%▲ +14.63%$1.85 (+18.86%)
Sep 29, 2026
28d ago
Press Release
BEARISH ★ 5/10
$2.28 $1.99▲ +12.72%▲ +14.63%$1.85 (+18.86%)
Sep 18, 2026
5w ago
6-K
BEARISH ★ 5/10
$1.79 $1.87▼ −4.47%▼ −3.20%$1.85 (−3.35%)
Sep 17, 2026
5w ago
6-K
BEARISH ★ 6/10
$1.79 $1.87▼ −4.47%▼ −3.20%$1.85 (−3.35%)
Sep 17, 2026
5w ago
Press Release
BEARISH ★ 5/10
$1.79 $1.87▼ −4.47%▼ −3.20%$1.85 (−3.35%)
Sep 16, 2026
5w ago
424B4
BEARISH ★ 7/10
$1.60 $1.88▼ −17.50%▼ −15.68%$1.85 (−15.63%)
Sep 16, 2026
5w ago
EFFECT
BEARISH ★ 7/10
$1.60 $1.88▼ −17.50%▼ −14.94%$1.85 (−15.63%)
Showing 10 of 18

US Market Status

Market Closed — Opens Wed (17h 17m)

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Report published Apr 27, 2026