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Institutional Cluster ·Filed Sep 22, 2026

CRBU

Caribou Biosciences, Inc.
MIXED
Impact 3/10
Horizonweeks Processed1mo ago
Institutional cluster: 26 buyers, 6 sellers (bullish)
Actionable Insight ◆ Mixed

The divergence between passive buying (Geode, Northern Trust, UBS) and active/quant selling (Millennium, Marshall Wace, Citadel, Point72, Susquehanna) suggests the stock is being accumulated by index-rebalancing flows while informed active managers reduce exposure. Monitor upcoming earnings and pipeline catalysts for signs of fundamental deterioration that could explain the active fund exits.

DirectionMixed
Confidencemedium
Horizonweeks
Latest settled — T+20d
CRBU ▼ -61.27% at T+20d
NEUTRAL call -61.27% · α vs SPY -60.71% · entry $1.34 → $0.5190
Next anchor: T+60d in 7w
Latest observation: T+23 -55.56% FF3 residual α
Entry = T+0 close
Sep 22, 2026
via day close
T+1d
-3.73%
call -3.73% · α -3.01%
$1.29
settled 5w ago
T+5d
-7.46%
call -7.46% · α -6.28%
$1.24
settled 28d ago
T+20d
-61.27%
call -61.27% · α -60.71%
$0.5190
settled 7d ago
T+60d
Pending
in 7w

Executive Summary

In Q2 2026, 26 institutional buyers accumulated $10.2M in CRBU (net +$4.7M), while 6 sellers reduced holdings by $5.7M. The buying is dominated by mega-passive funds (Geode, Northern Trust, UBS, Schwab) and asset managers (Dimensional, BNY Mellon), suggesting broad index-driven accumulation. However, notable active/quant sellers (Millennium, Marshall Wace, Citadel, Point72, Susquehanna) exited or trimmed heavily, creating a stark divergence between passive inflows and active outflows. The net institutional picture is mixed — passive buying may reflect rebalancing rather than conviction, while active fund exits signal caution on the company's prospects.

Key Financial Metrics

Direction
mixed
Buy Value
$10.2M
Sell Value
$5.7M
Net Flow
-$1.0M

Institutional Positions

Net institutional flow: -$1.0M

▲ Buyers (26)

InstitutionActionChangePosition ValueValue Δ
GeodeDOUBLED+133.3%$4.2M$2.2M
Northern TrustDOUBLED+227.4%$1.3M$841.0K
UBSADD+99.6%$911.0K$418.0K
Dimensional Fund AdvisorsADD+44.9%$1.7M$439.0K
Bank Of New York MellonDOUBLED+1678.9%$392.0K$368.0K

▼ Sellers (6)

InstitutionActionChangePrev ValueValue Δ
MillenniumNEAR_EXIT-95.2%$2.0M-$2.0M
Marshall WaceTRIM-68.8%$2.3M-$1.6M
Susquehanna International GroupNEAR_EXIT-80.2%$1.6M-$1.3M
Point72NEAR_EXIT-91.6%$356.0K-$329.0K
CitadelTRIM-74.6%$302.0K-$231.0K

Key Facts

  • 26 buyers vs 6 sellers in Q2 2026
  • Total buyer holdings: $10.2M (net change +$4.7M)
  • Total seller reductions: -$5.7M
  • Geode doubled its position (+133.3%) to $4.2M — largest buyer
  • Northern Trust more than doubled (+227.4%) to $1.3M
  • Bank of New York Mellon increased +1,678.9% to $392K
  • Millennium exited 95.2% of its position (-$2.0M)
  • Marshall Wace trimmed 68.8% (-$1.6M)
  • Susquehanna near-exited (-80.2%, -$1.3M)
  • Citadel trimmed 74.6% (-$231K)
  • Point72 near-exited (-91.6%, -$329K)
  • Morgan Stanley trimmed 50.5% (-$252K)

Financial Impact

26 institutions accumulated $10.2M in CRBU (net +$4.7M) while 6 institutions reduced holdings by $5.7M. The net institutional flow was approximately -$1.0M (buyer additions minus seller reductions).

institutional ownershipfloat

Risk Factors

  • Active/quant funds (Millennium, Marshall Wace, Citadel, Point72, Susquehanna) all reduced positions significantly — this is a strong bearish signal from sophisticated managers
  • Passive buying may be mechanical (index rebalancing) rather than conviction-based, providing no fundamental support
  • 13F data is 45 days stale; positions may have changed since quarter-end
  • Net institutional flow is negative (-$1.0M) when buyer additions are offset by seller reductions

Investment Themes

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-CRBU-2026-Q2
12 reports for CRBU
Performance horizon
33% Hit rate @ T+5 1 of 3 directional calls Went positive at some point 3 of 3 best @ T+5▲ +25.48%Oct 6, 2026
Filters
Rows
Reports for CRBU — sortable, filterable
TypeNow
Oct 6, 2026
20d ago
8-K
BEARISH ★ 7/10
$0.6174 $0.4601▲ +25.48%▲ +24.50%—
Sep 22, 2026
4w ago
Institutional Cluster
MIXED ★ 3/10
$1.34 $1.24▼ −7.46%▼ −6.28%—
Jun 11, 2026
19w ago
8-K
BULLISH ★ 6/10
$1.66 $1.64▼ −1.20%▼ −1.64%—
Jun 11, 2026
19w ago
Press Release
BULLISH ★ 7/10
$1.66 $1.64▼ −1.20%▼ −1.64%—
Jun 5, 2026
20w ago
DEFA14A
NEUTRAL ★ 2/10
$1.84 $1.66▼ −9.78%▼ −11.89%—
Apr 24, 2026
26w ago
DEFA14A
NEUTRAL ★ 3/10
$2.13 $1.91▼ −10.33%▼ −10.73%—
Mar 5, 2026
33w ago
8-K
MIXED ★ 5/10
$1.82 $1.88▲ +3.30%▲ +4.83%—
Mar 5, 2026
33w ago
Press Release
MIXED ★ 6/10
$1.82 $1.88▲ +3.30%▲ +4.83%—
Feb 28, 2026
34w ago
Institutional Cluster
NEUTRAL ★ 5/10
$1.84 $1.97▲ +7.07%▲ +8.27%—
Feb 24, 2026
34w ago
Insider Cluster
NEUTRAL ★ 3/10
$1.95 $1.80▼ −7.69%▼ −6.54%—
Showing 10 of 12

US Market Status

Market Closed — Opens in 59m

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Report published Sep 22, 2026