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S-1 ·Filed Jun 25, 2026

CELZ

CREATIVE MEDICAL TECHNOLOGY HOLDINGS, INC.
NEUTRAL
Impact 5/10
Horizonweeks Processed4mo ago SEC0001477932-26-004010
IPO registration
Actionable Insight • Neutral

Monitor the offering's closing and actual proceeds raised — the best-efforts structure with no minimum means the company may raise far less than the $5.34M target. Track progress of the CELZ-201 ADAPT and CREATE-1 clinical trials for catalysts. The large warrant overhang (6.1M shares at $7.72 exercise price vs. $1.97 market price) is deeply out-of-the-money and unlikely to be exercised, but the new public warrants (2 warrants per share at an undisclosed exercise price) could create future dilution if the stock appreciates.

DirectionNeutral
Confidencehigh
Horizonweeks
Final — all horizons settled through T+60d
CELZ ▼ -16.25% at T+60d
NEUTRAL call -16.25% · α vs SPY -20.74% · entry $1.20 → $1.01
Entry = T+0 close
Jun 25, 2026
via day close
T+1d
-32.48%
call -32.48% · α -34.13%
$0.8102
settled 4mo ago
T+5d
+0.83%
call +0.83% · α -1.33%
$1.21
settled 4mo ago
T+20d
-32.46%
call -32.46% · α -33.72%
$0.8105
settled 3mo ago
T+60d
-16.25%
call -16.25% · α -20.74%
$1.01
settled 5w ago

Executive Summary

Creative Medical Technology Holdings (CELZ) filed an S-1 registration statement for a best-efforts public offering of up to 3,045,685 shares of common stock and warrants to purchase up to 6,091,371 shares, plus pre-funded warrants, at an assumed combined price of $1.97 per share. The company is a clinical-stage biotechnology firm developing regenerative therapies for diabetes, chronic lower back pain, and other indications, with no approved products and minimal revenue. The offering is expected to raise approximately $5.34M in net proceeds to fund ongoing clinical trials and working capital, but there is no minimum offering amount, so proceeds could be substantially less.

Key Financial Metrics

Price Range
$1.97 per share and accompanying warrant (assumed, subject to negotiation)

Key Facts

  • Best-efforts offering of up to 3,045,685 shares of common stock and warrants to purchase up to 6,091,371 shares, plus pre-funded warrants
  • Assumed public offering price of $1.97 per share and accompanying warrant, based on June 23, 2026 closing price
  • Estimated net proceeds of approximately $5.34M, but no minimum offering amount required to close
  • Proceeds to fund Phase I/II clinical trials for chronic lower back pain (CELZ-201 ADAPT) and Type 1 Diabetes (CELZ-201 CREATE-1), plus iPSC program development
  • Company had $5.72M cash as of March 31, 2026; pro forma cash after offering ~$11.06M
  • 3,696,668 shares outstanding pre-offering; 6,742,353 pro forma (assuming no pre-funded warrants exercised)
  • Existing warrants outstanding for 6,097,915 shares at weighted-average exercise price of $7.72 per share
  • Roth Capital Partners acting as placement agent with 8.0% cash commission
  • 90-day lock-up for officers and directors; 180-day restriction on variable rate transactions
  • Company is a clinical-stage biotech with no approved products and minimal revenue

Financial Impact

Up to ~$6.0M gross proceeds at assumed price ($1.97 × 3,045,685 shares), with estimated net proceeds of ~$5.34M after 8% placement agent fees and ~$180K expenses. Actual proceeds may be substantially less due to best-efforts nature with no minimum.

dilutioncashshares outstanding

Risk Factors

  • Best-efforts offering with no minimum — may raise substantially less than $5.34M, potentially insufficient to fund operations through December 2027 as estimated
  • Clinical-stage company with no approved products, no revenue, and history of operating losses (accumulated deficit of $71.99M)
  • Immediate dilution of $0.37 per share to new investors (23% dilution from offering price of $1.97 to pro forma book value of $1.60)
  • Existing warrant overhang of 6.1M shares at $7.72 exercise price — deeply out-of-the-money but could create selling pressure if stock rallies
  • Nasdaq continued listing risk — company has a small market cap ($7M) and may face minimum bid price or other compliance issues
  • Pre-revenue biotech with high cash burn rate — will need additional capital beyond this offering to complete clinical development and achieve regulatory approval

Market Snapshot

Exchange
Nasdaq
Sector
Biological Products, (No Diagnostic Substances)
Analyst Consensus
86% bullish (7 analysts)

Investment Themes

Documents Analyzed

This report is based on 3 SEC documents filed with EDGAR.

DocumentAccession Number
S-1 Filing (Primary)0001477932-26-004010
Document: celz_ex1013.htm0001477932-26-004010
Document: celz_ex41.htm0001477932-26-004010
9 reports for CELZ
Performance horizon
67% Hit rate @ T+1 2 of 3 directional calls Went positive at some point 2 of 3 best @ T+20▲ +45.29%Jun 30, 2026
Filters
Rows
Reports for CELZ — sortable, filterable
TypeNow
Oct 1, 2026
25d ago
SC 13D
NEUTRAL ★ 4/10
$0.9464 $0.9200▼ −2.79%▼ −3.46%$0.6975 (−26.30%)
Sep 25, 2026
4w ago
8-K
MIXED ★ 5/10
$1.01 $0.9652▼ −4.44%▼ −4.25%$0.6975 (−30.94%)
Sep 17, 2026
5w ago
Press Release
NEUTRAL ★ 2/10
$0.8775 $0.9659▲ +10.07%▲ +10.19%$0.6975 (−20.51%)
Aug 20, 2026
9w ago
Press Release
NEUTRAL ★ 5/10
$1.28 $1.31▲ +2.34%▲ +1.93%$0.6975 (−45.51%)
Jul 1, 2026
16w ago
Press Release
NEUTRAL ★ 3/10
$1.27 $1.21▼ −4.72%▼ −4.59%$0.6975 (−45.08%)
Jun 30, 2026
17w ago
Press Release
BEARISH ★ 7/10
$1.45 $1.27▲ +12.41%▲ +12.28%$0.6975 (+51.90%)
Jun 26, 2026
17w ago
S-1/A
BEARISH ★ 6/10
$0.8102 $1.45▼ −78.97%▼ −78.19%$0.6975 (+13.91%)
Jun 25, 2026
17w ago
S-1
NEUTRAL ★ 5/10
$1.20 $0.8102▼ −32.48%▼ −34.13%$0.6975 (−41.88%)
Jun 22, 2026
18w ago
Press Release
BULLISH ★ 6/10
$1.93 $1.97▲ +2.07%▲ +3.52%$0.6975 (−63.86%)
Showing 9 of 9

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Report published Jun 25, 2026