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424B5 ·Filed Jul 14, 2026

CBIO

CRESCENT BIOPHARMA, INC.
BEARISH
Impact 6/10
Horizonimmediate Processed3mo ago SEC0001628280-26-048144
Notable filing: 424B5
Actionable Insight ▼ Bearish

Monitor for the final offering size and pricing in the subsequent 424B5 filing. The dilutive impact will depend on the number of shares sold relative to the 27.6M shares outstanding. The company's cash runway extends into 2028 per the filing, but this raise suggests accelerated spending on clinical trials.

DirectionBearish
Confidencemedium
Horizonimmediate
Final — all horizons settled through T+60d ⚠ clustered
CBIO ▼ -9.89% at T+60d
SHORT call ✓ call won +9.89% · α vs SPY +12.42% · entry $15.67 → $14.12
Entry = T+0 close
Jul 14, 2026
via day close
T+1d
-3.57%
call +3.57% · α +3.03%
$15.11
settled 4mo ago
T+5d
+1.02%
call -1.02% · α -2.00%
$15.83
settled 3mo ago
T+20d
+4.85%
call -4.85% · α -2.51%
$16.43
settled 3mo ago
T+60d
-9.89%
call +9.89% · α +12.42%
$14.12
settled 21d ago

Price Chart

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Executive Summary

Crescent Biopharma filed a preliminary prospectus supplement for an underwritten offering of ordinary shares and pre-funded warrants. The offering size and pricing are not yet disclosed, but the company had approximately $171.6M in cash as of June 30, 2026. This dilutive capital raise for a clinical-stage biotech with no revenue signals a need for additional funding to support clinical development of its pipeline (CR-001, CR-002, CR-003).

Key Facts

  • Offering of ordinary shares and pre-funded warrants; terms (size, price) are preliminary and not yet disclosed.
  • Company had approximately $171.6M in cash and cash equivalents as of June 30, 2026 (preliminary, unaudited).
  • Stock closed at $15.69 on July 13, 2026; market cap ~$433M.
  • Underwriters include Jefferies, TD Cowen, Guggenheim, Cantor, and LifeSci Capital.
  • Company has a $200M ATM facility with Jefferies (dated July 1, 2026) but agreed not to sell under it until the earlier of full exercise of the underwriters' option or 30 days after this prospectus supplement.
  • 60-day lock-up for officers, directors, and certain stockholders.
  • Pre-funded warrants have an exercise price of $0.001 and do not expire until fully exercised.

Financial Impact

Undisclosed amount; offering will be dilutive to existing shareholders. Company had $171.6M cash as of June 30, 2026.

dilutioncash

Risk Factors

  • Offering size unknown but likely material relative to $433M market cap.
  • Clinical-stage biotech with no revenue; all pipeline candidates are in early trials.
  • Potential further dilution from the $200M ATM facility after the lock-up period.
  • Pre-funded warrants may be exercised, adding to share count with minimal additional proceeds.

Market Snapshot

Exchange
Nasdaq
Sector
Pharmaceutical Preparations
Analyst Consensus
87% bullish (15 analysts)

Investment Themes

Documents Analyzed

This report is based on 4 SEC documents filed with EDGAR.

DocumentAccession Number
424B5 Filing (Primary)0001628280-26-048144
Document: 0001628280-26-048144-index-headers.html0001628280-26-048144
Document: 0001628280-26-048144-index.html0001628280-26-048144
Document: 0001628280-26-048144.txt0001628280-26-048144
16 reports for CBIO
Performance horizon
67% Hit rate @ T+60 2 of 3 directional calls Went positive at some point 3 of 3 best @ T+60▲ +9.89%Jul 14, 2026
Filters
Rows
Reports for CBIO — sortable, filterable
TypeNow
Oct 15, 2026
12d ago
8-K
NEUTRAL ★ 3/10
$11.84awaiting T+60—$13.27 (+12.08%)
Oct 15, 2026
12d ago
Press Release
NEUTRAL ★ 4/10
$11.84awaiting T+60—$13.27 (+12.08%)
Oct 5, 2026
22d ago
Press Release
NEUTRAL ★ 4/10
$13.94awaiting T+60—$13.27 (−4.81%)
Sep 18, 2026
5w ago
Insider Cluster
NEUTRAL ★ 3/10
$16.25awaiting T+60—$13.27 (−18.34%)
Jul 30, 2026
12w ago
8-K
NEUTRAL ★ 3/10
$15.02 $12.82▼ −14.65%▼ −17.11%$13.27 (−11.65%)
Jul 20, 2026
14w ago
Insider Buy
BULLISH ★ 7/10
$16.64 $12.91▼ −22.42%▼ −26.39%$13.27 (−20.25%)
Jul 15, 2026
14w ago
8-K / 424B5
BEARISH ★ 6/10
$15.11 $14.91▲ +1.32%▲ +5.03%$13.27 (+12.18%)
Jul 14, 2026
15w ago
Press Release
BEARISH ★ 7/10
$15.67 $14.12▲ +9.89%▲ +12.42%$13.27 (+15.32%)
Jul 14, 2026
15w ago
424B5
BEARISH ★ 6/10
$15.67 $14.12▲ +9.89%▲ +12.42%$13.27 (+15.32%)
Jul 13, 2026
15w ago
EFFECT
NEUTRAL ★ 3/10
$15.69 $13.57▼ −13.51%▼ −17.51%$13.27 (−15.42%)
Showing 10 of 16

US Market Status

Market Closed — Opens Thu (10h 20m)

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Report published Jul 14, 2026