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Insider Cluster (2 insiders) ·Filed Sep 23, 2026

CAI

Caris Life Sciences, Inc.
BEARISH
Impact 6/10
Horizonweeks Processed1mo ago
Insider cluster: 2 insiders, $12.4M total
Actionable Insight ▼ Bearish

CEO Brille's large open-market sale after a derivative exercise is a strong negative signal, especially with no insider buying to offset it. Monitor for any upcoming earnings miss, guidance cut, or material adverse news that may have prompted the selling.

DirectionBearish
Confidencehigh
Horizonweeks
Latest settled — T+20d
CAI ▼ -1.74% at T+20d
SHORT call ✓ call won +1.74% · α vs SPY +1.32% · entry $32.27 → $31.71
Next anchor: T+60d in 7w
Latest observation: T+21 +17.56% FF3 residual α
Entry = T+0 close
Sep 23, 2026
via day close
T+1d
-0.90%
call +0.90% · α +1.44%
$31.98
settled 5w ago
T+5d
-12.15%
call +12.15% · α +11.73%
$28.35
settled 27d ago
T+20d
-1.74%
call +1.74% · α +1.32%
$31.71
settled 6d ago
T+60d
Pending
in 7w

Price Chart

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Executive Summary

Two Caris Life Sciences insiders, including CEO Brian Brille, sold a total of $12.37M in shares within a week. Brille's $12.13M open-market sale followed a derivative exercise at a fraction of the market price, netting a large cash gain. The selling is material relative to the company's market cap and is not offset by any insider buying.

Key Financial Metrics

Direction
selling
Total Value
$12.4M
Insiders
2

Key Facts

  • CEO Brian Brille sold 400,000 shares for $12.13M on 2026-09-17 at $30.33/share
  • Brille's sale followed exercise of derivatives at $2.44/share, realizing a large gain
  • Director John Russel Denton sold 7,500 shares for $239K on 2026-09-22 at $31.82/share
  • Total insider sales of $12.37M in a 7-day window with zero insider purchases
  • No 10b5-1 plan indicated for either sale

Financial Impact

Total insider sales of $12.37M represent approximately 3.8% of the company's $326M market cap, a highly material proportion

dilutioninsider ownership

Risk Factors

  • CEO selling a large stake may signal deteriorating business fundamentals or upcoming bad news
  • No insider buying suggests management lacks confidence in near-term prospects
  • The derivative exercise at $2.44 followed by immediate sale at $30.33 indicates profit-taking rather than conviction

Investment Themes

Healthcare & Medical Devices

Documents Analyzed

This report is based on 1 SEC document filed with EDGAR.

DocumentAccession Number
CLUSTER Data (Synthetic)cluster-CAI-1790197641893
8 reports for CAI
Performance horizon

Track record builds as more directional reports settle.

Filters
Rows
Reports for CAI — sortable, filterable
TypeNow
Oct 20, 2026
6d ago
Institutional Cluster
BULLISH ★ 4/10
$32.35awaiting T+20—$32.50 (+0.46%)
Oct 15, 2026
12d ago
Press Release
NEUTRAL ★ 1/10
$31.76awaiting T+20—$32.50 (+2.33%)
Sep 23, 2026
4w ago
Insider Cluster
BEARISH ★ 6/10
$32.27 $31.71▲ +1.74%▲ +1.32%$32.50 (−0.71%)
Sep 14, 2026
6w ago
8-K
NEUTRAL ★ 2/10
$28.50 $29.53▲ +3.61%▲ +0.89%$32.50 (+14.04%)
Aug 7, 2026
11w ago
144
BEARISH ★ 5/10
$23.40 $24.82▼ −6.07%▼ −6.98%$32.50 (−38.89%)
Jul 13, 2026
15w ago
Insider Cluster
BULLISH ★ 5/10
$17.06 $23.40▲ +37.16%▲ +33.98%$32.50 (+90.50%)
Jun 11, 2026
19w ago
Institutional Cluster
NEUTRAL ★ 3/10
$18.00 $17.87▼ −0.72%▼ −2.61%$32.50 (+80.56%)
Apr 23, 2026
26w ago
DEFA14A
NEUTRAL ★ 2/10
$19.79 $15.70▼ −20.67%▼ −25.30%$32.50 (+64.22%)
Showing 8 of 8

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Report published Sep 23, 2026