SecBot SecBot
Institutional Cluster ·Filed Oct 20, 2026

AXSM

Axsome Therapeutics, Inc.
BEARISH
Impact 4/10
Horizonweeks Processed7d 3h ago
Institutional cluster: 1 buyers, 3 sellers (bearish)
Actionable Insight ▼ Bearish

The concentrated selling by three active asset managers, especially Assenagon's $65M trim, signals a coordinated negative view. Monitor for any fundamental catalyst (pipeline update, revenue miss, regulatory setback) that could explain the exodus. The 45-day reporting lag means these positions may have been adjusted further since quarter-end.

DirectionBearish
Confidencemedium
Horizonweeks
Latest settled — T+1d
AXSM ▼ -0.15% at T+1d
SHORT call ✓ call won +0.15% · α vs SPY -1.03% · entry $156.31 → $156.07
Next anchor: T+5d due 12h ago
Latest observation: T+2 +4.84% FF3 residual α
Entry = T+0 close
Oct 20, 2026
via day close
T+1d
-0.15%
call +0.15% · α -1.03%
$156.07
settled 6d ago
T+5d
Pending
due 12h ago
T+20d
Pending
in 21d
T+60d
Pending
in 3mo

Executive Summary

Three institutional asset managers trimmed or exited AXSM positions in Q3 2026, led by Assenagon Asset Management reducing its stake by $65M (-44.8% shares). Only one small buyer (Concurrent Investment Advisors) added a modest $448K. The net institutional flow is decisively bearish at -$64.8M, suggesting a shared negative thesis on Axsome's near-term prospects.

Key Financial Metrics

Direction
distributing
Buy Value
$873.0K
Sell Value
$111.6M
Net Flow
-$64.8M

Institutional Positions

Net institutional flow: -$64.8M

▲ Buyers (1)

InstitutionActionChangePosition ValueValue Δ
Concurrent Investment AdvisorsDOUBLED+172.4%$873.0K$448.0K

▼ Sellers (3)

InstitutionActionChangePrev ValueValue Δ
Assenagon Asset ManagementTRIM-44.8%$111.3M-$65.0M
Nisa Investment AdvisorsTRIM-55.9%$215.0K-$144.0K
Farther Finance AdvisorsTRIM-27.4%$126.0K-$57.0K

Key Facts

  • 3 sellers vs 1 buyer in Q3 2026 institutional cluster
  • Assenagon Asset Management trimmed 44.8% of its AXSM position, selling $65.0M in value
  • Net institutional outflow: -$64.8M (sellers $65.2M vs buyers $0.4M)
  • Only one buyer (Concurrent Investment Advisors) added $448K, a small position
  • All four funds are active asset managers — no passive/index funds in the cluster

Financial Impact

Three institutional sellers reduced AXSM holdings by $65.2M in aggregate, while one buyer added $0.4M, resulting in a net outflow of $64.8M.

institutional ownershipfloatsentiment

Risk Factors

  • 13F data is 45+ days stale; the selling may have already been completed or reversed
  • Only 3 sellers — not a broad-based institutional exodus
  • No insider buying to corroborate a contrarian thesis

Investment Themes

Documents Analyzed

This report is based on 1 institutional 13F filing from SEC EDGAR.

DocumentAccession Number
INST-CLUSTER Data (Synthetic)inst-cluster-AXSM-2026-Q3
24 reports for AXSM
Performance horizon
83% Hit rate @ T+5 5 of 6 directional calls Went positive at some point 5 of 6 best @ T+60▲ +14.74%Apr 30, 2026
Filters
Rows
Reports for AXSM — sortable, filterable
TypeNow
Oct 20, 2026
7d ago
Institutional Cluster
BEARISH ★ 4/10
$156.31awaiting T+5——
Aug 11, 2026
11w ago
Institutional Cluster
MIXED ★ 5/10
$214.66 $218.20▲ +1.65%▲ +2.09%—
Aug 10, 2026
11w ago
8-K
NEUTRAL ★ 6/10
$220.89 $216.27▼ −2.09%▼ −2.04%—
Aug 10, 2026
11w ago
Press Release
MIXED ★ 6/10
$220.89 $216.27▼ −2.09%▼ −2.04%—
Jul 15, 2026
14w ago
Press Release
BULLISH ★ 6/10
$237.53 $239.62▲ +0.88%▲ +1.86%—
Jul 9, 2026
15w ago
Court Ruling
BULLISH ★ 5/10
$248.95 $237.04▼ −4.78%▼ −4.65%—
Jul 7, 2026
16w ago
Press Release
NEUTRAL ★ 4/10
$249.76 $235.26▼ −5.81%▼ −6.36%—
Jul 1, 2026
16w ago
144
NEUTRAL ★ 4/10
$244.31 $248.95▲ +1.90%▲ +0.97%—
Jun 15, 2026
19w ago
Press Release
NEUTRAL ★ 3/10
$253.40 $247.85▼ −2.19%▼ −0.81%—
Jun 11, 2026
19w ago
Insider Cluster
NEUTRAL ★ 4/10
$255.17 $250.50▼ −1.83%▼ −2.50%—
Showing 10 of 24

US Market Status

Market Closed — Opens Wed (< 1m)

Subscribe to SecBot

Get Real-Time SEC Filing Intelligence

Comprehensive SEC filing analysis delivered the moment filings hit EDGAR. Sentiment scoring, impact analysis, and actionable insights for every material event.

Create a free account Live analysis, Telegram alerts, watchlists and the MCP server for subscribers
Report published Oct 20, 2026